Cancer Type: Gastrointestinal Tumor
Study Type: Treatment
Phase: Phase II
Principal Investigator: Kim, Richard
Phase 2, Multicenter, Open-Label Basket Study of Navicixizumab Monotherapy or in Combination with Paclitaxel or Irinotecan in Patients with Select Advanced Solid Tumors
This is a study of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced cancer.
To investigate the antitumor activity of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced solid tumors including: − Cohort A: CRC − Cohort B: Gastric and GEJ cancer − Cohort C: TNBC − Cohort D: Platinum-resistant/refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer. Note: For Cohort D, the diagnoses are collectively referred to ovarian cancer throughout the protocol.
Chemotherapy (NOS); Immunotherapy
CPT-11 (irinotecan); Camptosar (irinotecan); Navicixizumab (); OMP-305B83 (Navicixizumab); Taxol (paclitaxel); irinotecan (); paclitaxel ()
If you are interested in learning more about clinical trials, our clinical trial navigators can discuss your options and recommend opportunities that may be suitable for you. Call 813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.
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