Cancer Type: Malignant Hematology
Study Type: Treatment
Phase: Phase I
Principal Investigator: Jain, Michael
A Phase 1 Study of PBCAR19B in Subjects with CD19-expressing Malignancies
This is a Phase 1, nonrandomized, open-label, single-dose, dose-escalation, and dose-expansion study to evaluate the safety and clinical activity of PBCAR19B in adult study participants with CD-19 expressing malignancies.
Primary: -To evaluate the safety and tolerability of PBCAR19B in subjects with relapsed/refractory Non-Hodgkin Lymphoma (r/r NHL) and find an appropriate dose to optimize safety and efficacy. Secondary: -To evaluate the clinical activity of PBCAR19B in subjects with r/r NHL.
Cell Therapy; Chemotherapy (NOS); Therapy (NOS)
If you are interested in learning more about clinical trials, our clinical trial navigators can discuss your options and recommend opportunities that may be suitable for you. Call 813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.
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