A Phase 2 Study of ALX148 in Combination with Pembrolizumab and chemotherapy in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)
A Phase 2 Study of Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma.
* To assess the effect of ALX148 plus pembrolizumab + chemotherapy on overall response rate (ORR) in patients with metastatic or unresectable, recurrent HNSCC who have not yet been treated for their advanced disease.
* To assess secondary measures of efficacy for ALX148 administered in combination with pembrolizumab + chemotherapy and for pembrolizumab + chemotherapy alone.
* To assess the safety and tolerability of ALX148 administered in combination with pembrolizumab + chemotherapy and for pembrolizumab + chemotherapy alone.
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