Clinical Trials Search
Clinical Study of the Utility of a Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas
5-ALA and the Orbeye surgical microscope are U.S. Food and Drug Administration (FDA) approved products. For this study, however, the Orbeye microscope imaging system is being used with special filters to visualize 5-ALA fluorescence. The FDA currently permits the use of these filters. The purpose of this study is to collect medical information before, during, and after standard treatment in order to better understand how to make this type of procedure accessible to patients.
This study will assess the utility of a novel FDA-cleared exoscope surgical microscope equipped with a blue-light filter set to perform 5-ALA fluorescence-guided surgery for high-grade gliomas. The hypothesis is that visualization of 5-ALA fluorescence with the use of the exoscope during a standard clinically indicated glioma surgery will provide sufficient realtime visualization of residual tumor tissue and/or tumor-infiltrated brain tissue.
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