A Pre-Pilot of a Survivor-Personalized Colorectal Cancer Screening Education Intervention for Adult First-Degree Relatives
The purpose of this study is to get feedback from both colorectal cancer survivors and first-degree relatives such as parents, siblings, and children of colorectal cancer survivors on the best ways to personalize, deliver, and promote colorectal cancer screening through educational materials for first-degree relatives that will be personalized by their colorectal cancer survivor
relative, develop educational materials based upon that feedback, and then see whether colorectal cancer survivors and first-degree relatives receive feedback on the process and how well the process works
Aim 1 (Phase I/Formative Phase): Develop a personalized educational intervention acceptable to both CRC survivors and FDRs aimed at promoting CRC screening among FDRs not currently adherent to screening guidelines. This will be accomplished via a sequential series of 3 focus groups (one with CRC survivors only, one with FDRs only, and the last with both CRC survivors and FDRs) with approximately 10 participants each for a total of 30 participants (i.e., 15 CRC survivors and 15 FDRs) and a process of iterative refinement of the intervention materials and processes. This phase will provide important direction for the intervention in terms of the personalized message creation process, content, and delivery preferences (e.g., number, order, format, timing, delivery method). This phase will also produce a bank of example messages that will illustrate the creation of theory-based messages to survivors enrolled in future trials. Ultimately, this phase will result in an advanced draft of the intervention materials and processes
Aim 2 (Phase II/Pre-pilot Phase): Examine the feasibility, acceptability, and proof of concept of a CRC survivor-personalized intervention to increase FDRs CRC knowledge and screening intentions. This will be accomplished through a single-arm (non-randomized) pre-pilot study which includes individual phone interviews with 25 dyads of CRC survivors and FDRs. In this phase, we will examine the feasibility and acceptability of implementing the intervention. Specifically, we will demonstrate that survivors can create personalized messages for their related FDR and that these messages are acceptable to FDRs. This phase is expected to demonstrate proof of concept for a planned National Cancer Institute modular R01 application for an RCT aimed at evaluating whether the survivor-personalized message intervention improves FDRs CRC knowledge, encourages CRC screening discussions, improves screening intentions among FDRs, and promotes CRC screening uptake among FDRs compared to non-personalized education
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