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Clinical Trial 19740

Cancer Type: Healthy Subjects
Interventions:

Study Type: Other
Phase of Study: N/A
Investigators:

  • David Evans

Call 813-745-6100
or 1-800-679-0775
Overview

Study Title

Acute Effects of Brief Mindfulness Exercises on the Processing of Smoking Cues and Craving

Summary

Objective

Specific Aim 1: Test the acute impact of mindfulness practices on smoking cue processing and related craving. Specific Aim 2: Examine the role of response inhibition as a facet of cognitive control as a potential mechanism linking mindfulness with reduced smoking cue processing Specific Aim 3: Test the validity of behavioral and neural markers of subliminal smoking cue processing

Inclusion Criteria

  • Between 18 and 55 years of age
  • Cigarette smoker who is not actively attempting to quit
  • Smokers who have smoked for at least an average of 10 or more cigarettes per day for the past 2 years and urine cotinine levels indicative of being a current daily smoker as indicated by NicAlert (Nymox Pharmaceutical, Inc.) test;
  • Able to read and understand the consent forms, questionnaires and instructions.

  • Exclusion Criteria

  • Serious head injury (e.g., concussion)
  • Current psychoactive substance abuse (e.g., cocaine, amphetamines, barbiturates, benzodiazepines as assessed via both self-report and urine drug test)
  • Currently on medications that may affect physiological responding (e.g., benzodiazepines, beta blockers, neuroleptics, selective serotonin reuptake inhibitors, and tricyclic antidepressants).
  • Serious medical conditions (e.g., cardiopulmonary problems, cancer, major life threatening illnesses)
  • Currently taking Bupropion (Zyban) or Varenicline (Chantix)
  • Vision problems (i.e., corrected normal vision acceptable) > Women who are pregnant (due to smoking in the lab)
  • Current DSM-V71 psychosis (as measured via brief psychiatric interview).
  • Other exclusions may apply.