Clinical Trial 19131

Cancer Type: Malignant Hematology
Interventions:

Study Type: Supportive Care
Phase of Study: NA
Investigators:

  • Heather Jim

Overview

Study Title

Contribution of Sleep Disruption and Physical Inactivity to Fatigue In Survivors of Allogeneic Hematopoietic Cell Transplant

Summary

While relationships between self-reports of sleep, activity, and fatigue are well characterized, relationships between objectively measured sleep and activity with self-reported fatigue are not well understood. Moreover, even less is known about the impact of daily sleep and activity on daily fatigue. Given these key unanswered questions, the proposed study will characterize fatigue among allogeneic HCT patients and investigate relationships of sleep and sedentary behavior with fatigue. The study participants will include adults who underwent an allogeneic HCT at Moffitt Cancer Center for treatment of a hematologic disease.

Objective

Aim 1: To characterize the prevalence and daily variability of fatigue among allogeneic HCT survivors. Aim 2: To investigate the relative contribution of aggregated daily fatigue and summary fatigue to aggregated sleep disruption. Aim 3: To investigate the relative contribution of aggregated daily fatigue and summary fatigue to aggregated sedentary behavior. Aim 4: To explore whether sleep disruption during the previous night and sedentary behavior during the day are related to evening reports of fatigue.

Inclusion Criteria

  • Eligible patients returning to clinic for an appointment will be approached during their clinic visit and will have the study protocol explained to them.
  • Eligible participants must: 1) be diagnosed with a hematologic malignancy;
  • have undergone an allogeneic HCT approximately 1 to 5 years prior to study enrollment;
  • be ≥18 years of age;
  • have no history of other cancers other than non-melanoma skin cancer;
  • have no evidence of disease progression at the time of study enrollment;
  • have ambulatory patient status at the time of study enrollment;
  • have internet access;
  • be able to speak and read English;
  • be able to provide informed consent.