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Clinical Trial 18999

Cancer Type: Thoracic
Study Type: Other

Phase: N/A
Prinicipal Investigator:

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Study Title

Early Detection of Cancer Progression: Leveraging Team Science


The purpose of this study is to identify patterns of patient-reported outcomes (PROs) that are predictors of cancer progression, explore the relationship between tumor size and PROs, and develop software to collect PROs from patients remotely via the Internet. Investigators plan to use this information to evaluate whether PROs may be used as an early indicator of cancer progression in the future. Investigators will prospectively recruit 50 lung cancer patients to participate in this study.


Aim 1: To identify patterns of patient-reported symptoms that are early indicators of lung cancer progression. Aim 2: To explore the minimum increase in lung tumor volume detectable by patient-reported symptoms. Aim 3: To develop software to collect patient-reported symptom data between clinic visits.




Inclusion Criteria

  • Diagnosed with Stage IV Non-small Cell Lung Cancer (NSCLC)
  • Have radiographically assessable disease in the lung at baseline
  • Starting chemotherapy with an immune checkpoint inhibitor (i.e., PD1 or PD-L1)
  • Able to speak and read English
  • Have Internet access
  • Able to provide informed consent

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