Clinical Trials Search
Clinical Trial 18776
Cancer Type: Breast
Interventions:HER-2 Pulsed-DC Vaccine
Study Type: Treatment
Phase of Study: Phase I
Multisite Pilot Phase I HER-2 Pulsed-DC Vaccine to Prevent Recurrence for Patients with HER-2 Driven High Risk Invasive Breast Cancer Post Neoadjuvant Chemotherapy
The main goals of the study are: 1. To determine safety of the study vaccine; 2. To determine whether the study vaccine can provoke an immune response; 3. To determine whether circulating tumor cells can be used to assess response to vaccination.
The primary objectives are to determine feasibility and safety. The secondary objectives are to evaluate immunogenicity and anti-HER2 immunity.