Clinical Trial 18643

Cancer Type: Genitourinary
Interventions:

Study Type: Other
Phase of Study: NA
Investigators:

  • Jong Park

Overview

Study Title

Biobank for African American Prostate Cancer Research in Florida

Summary

The purposes of this study are: a) to develop a statewide Biobank for prostate cancer among men of African Ancestry in Florida and; b) to examine whether smoking increases the aggressiveness of prostate cancer using several biological approaches. Investigators plan to contact African American prostate cancer patients regarding participation. This project has 3 main components. Eligible patients may choose to participate in any or all parts of the study: Questionnaires; Saliva Samples; Tumor Tissue.

Objective

Aim 1. To collect and manage detailed patients' data, outcome information and bio-specimens from men of African Ancestry with prostate cancer (n=6,000), diagnosed between Jan 2013 and Dec. 2015. Aim 2. To test the hypothesis that smoking increases the aggressiveness of prostate cancer using epidemiological and molecular biological approaches. 2A. To estimate the impact of smoking in prostate cancer aggressiveness. 2B. To identify genetic and epigenetic changes associated with smoking and aggressiveness in prostate tumor samples.

Inclusion Criteria

  • The initial recruitment of cases will be done with 3 mailings: the first to introduce the study to the participant from Florida Cancer Data System (FCDS) of the Florida Department of Health and ask them to complete the eligibility form and contact information update form; a second mailing to those who are determined to be eligible for the study to obtain the Informed Consent Form and the Baseline survey; and a third mailing to those who completed the survey to obtain a saliva sample and medical release form for tissue.
  • Histologically biopsy confirmed, primary prostate cancer, diagnosed between January 2013 and December 2015
  • African American or Black; Hispanic Black; Afro-Caribbean
  • Are at least 20 years old
  • Are a resident of Florida
  • Additional criteria may apply

  • Exclusion Criteria

    Does not meet Inclusion Criteria