Clinical Trial 18365

Cancer Type: Malignant Hematology
Interventions:

Study Type: Supportive Care
Phase of Study: NA
Investigators:


    Overview

    Study Title

    Preliminary Evaluation of an Internet-Assisted Cognitive Behavioral Intervention for Targeted Therapy Fatigue

    Summary

    The purpose of this study is to explore the efficacy of cognitive behavioral therapy (CBT) in addressing target therapy-related fatigue (TTF), CBT-TTF.

    Objective

    1) Evaluate CBT-TTF and related methods for feasibility and acceptability; 2) Explore the efficacy of CBT-TTF in reducing fatigue (primary outcome); 3) Explore the efficacy of CBT-TTF in improving quality of life and oral medication adherence (secondary outcomes); and 4) Explore the efficacy of CBT-TTF in modifying factors identified as intervention targets (tertiary outcomes).

    Inclusion Criteria

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  • Potential participants will be contacted by the study coordinator. Participants must:
  • be >=18 years old
  • be able to speak/read English
  • be diagnosed with chronic phase chronic myelogenous leukemia (CML)
  • not have been treated for other cancer (except non-melanoma skin cancer) in the past 5 years
  • be under the care of a Moffitt Cancer Center (MCC) physician
  • be on a stable dose of the same oral tyrosine kinase inhibitor (TKI) for >=3 months
  • have new onset or worsening of fatigue since starting TKI
  • report moderate-severe fatigue in past week (FSI average rating >= 4 of 0-10)
  • have no clinical history of disease (e.g., multiple sclerosis, fibromyalgia) that could account for their fatigue presentation

  • Exclusion Criteria

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  • Scheduled to discontinue their TKI under medical supervision within the next 3 months