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Clinical Trial 17071
Cancer Type: Malignant Hematology
Study Type: Treatment
Phase of Study: Phase I/II
Ofatumumab in Combination with Glucocorticoids for Primary Therapy of Chronic Graft vs. Host Disease
Investigators plan to study the safety and side effects of Ofatumumab in the treatment of chronic graft-versus-host disease (GvHD). This study will also evaluate effectiveness of Ofatumumab when added to standard steroid treatment for chronic graft-versus-host disease.
Phase I- Determine safety of ofatumumab in combination with steroids in the primary therapy of chronic GVHD. Phase II- Determine overall response rate (CR+PR) at 6 months to ofatumumab and glucocorticoid primary therapy of chronic GVHD.