What Causes Ovarian Cancer?

What causes ovarian cancer? The specifics are unclear. In general, ovarian cancer, like other forms of cancer, develops when genetic mutations transform normal, healthy cells into abnormal cells that divide and multiply in an unorderly fashion. The resulting accumulation of cells can form a tumor that may become malignant, invade nearby tissues and sometimes spread to other tissues and organs throughout the body. While the causes of ovarian cancer are not completely understood, the scientific community continues to make progress in learning how certain DNA mutations that occur in the cells of the ovaries can lead to a buildup that eventually becomes cancerous. Several theories are currently under study, including the role of:

  • Inherited mutations in the BRCA1 and BRCA2 genes, both of which are normally involved in DNA repair
  • Acquired genetic changes that occur during a woman’s lifetime as a result of radiation or chemical exposure

At Moffitt Cancer Center, we are strongly committed to conducting groundbreaking research and promising clinical trials dedicated to the prevention, diagnosis and treatment of ovarian cancer and other types of cancer. This focus ensures that we remain firmly positioned at the forefront of cancer care. In recognition of our efforts, the National Cancer Institute has designated Moffitt as the only Comprehensive Cancer Center in Florida. We are proud to have earned this prestigious distinction as we work to improve survival rates and patient quality of life.

To learn more from the cancer experts at Moffitt about what causes ovarian cancer, please call 1-888-MOFFITT or schedule an appointment online. Our physicians will be pleased to consult with you, even if you don’t have a referral.