Image Response Assessment Team

Where You Are:

The Image Response Assessment Team (IRAT) Core facility uses state-of the art imaging equipment for patient studies and its extensive facilities for preclinical investigations. The Core’s equipment is also shared with the clinical Department of Diagnostic Imaging for research scans to aid clinical work. Major equipment includes: 

  • Six multi-detector CT scanners with up to 64 detector rows used for patient studies
  • Three 1.5 T MR scanners for clinical scanning, including diffusion weighted imaging
  • Moffitt’s Section of Nuclear Medicine in the Department of Diagnostic Imaging is a state-of-the-art facility that performs large numbers of clinical and clinical research studies, amounting to >30 PET/CT scans per day
  • A cyclotron, a clinical SPECT/CT and 3 additional PET/CTs
  • Image reading and tumor size measurements are made on an Emageon PACS system. Dedicated data storage for raw-data archiving is available for research-related scans

 IRAT Core facility services include:

  • “One-stop” access to IRAT services and a central point of contact to ensure that projects are carried out with special attention to the flow of patients and information
  • Coordination of acquisition and analysis of radiological images for clinical trials
  • Maintaining the quality of reported quantitative data and rapid response time
  • Expanding the quantitative nature of reporting through more detailed image analysis. Software packages can be used to segment lesions and generate quantitative reports of tumor features, including size, shape, and texture features.
  • Consulting on clinical study development
  • Assisting investigators in identifying appropriate radiological markers and response measurements
  • Providing pilot data for grant submissions
  • Assisting in the development of non-traditional imaging endpoints for response assessment, including participation in American College of Radiology Imaging Network 

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