Susan C. Frost, PhD

Where You Are:
Susan C. Frost, PhD

Office  (352) 392-3207

Education And Training
  • PhD, University of Arizona, 1979 - Biochemistry

  • Whittamore JM, Frost SC, Hatch M. Effects of acid-base variables and the role of carbonic anhydrase on oxalate secretion by the mouse intestine in vitro. Physiol Rep. 2015 Feb;3(2). Pubmedid: 25716924. Pmcid: PMC4393191.
  • McKenna R, Frost SC. Overview of the carbonic anhydrase family. Subcell Biochem. 2014 Oct;75:3-5. Pubmedid: 24146371.
  • Frost SC. Physiological functions of the alpha class of carbonic anhydrases. Subcell Biochem. 2014 OCT;75:9-30. Pubmedid: 24146372.
  • Grobmyer SR, Morse DL, Fletcher B, Gutwein LG, Sharma P, Krishna V, Frost SC, Moudgil BM, Brown SC. The promise of nanotechnology for solving clinical problems in breast cancer. J Surg Oncol. 2011 Mar;103(4):317-325. Pubmedid: 21337565.
  • Delacruz J, Mikulski R, Tu C, Li Y, Wang H, Shiverick KT, Frost SC, Horenstein NA, Silverman DN. Detecting extracellular carbonic anhydrase activity using membrane inlet mass spectrometry. Anal Biochem. 2010 Aug;403(1-2):74-78. Pubmedid: 20417171. Pmcid: PMC2893724.
  • Li Y, Wang H, Oosterwijk E, Selman Y, Mira JC, Medrano T, Shiverick KT, Frost SC. Antibody-specific detection of CAIX in breast and prostate cancers. Biochem Biophys Res Commun. 2009 Aug;386(3):488-492. Pubmedid: 19538935. Pmcid: PMC2760152.
  • Li Y, Wang H, Oosterwijk E, Tu C, Shiverick KT, Silverman DN, Frost SC. Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells. Cancer Invest. 2009 Jul;27(6):613-623. Pubmedid: 19367501. Pmcid: PMC2873695.
  • Kumar A, Xiao YP, Laipis PJ, Fletcher BS, Frost SC. Glucose deprivation enhances targeting of GLUT1 to lipid rafts in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E568-E576. Pubmedid: 14665446.
  • Hwang JB, Hernandez J, Leduc R, Frost SC. Alternative glycosylation of the insulin receptor prevents oligomerization and acquisition of insulin-dependent tyrosine kinase activity. Biochim Biophys Acta. 2000 Dec;1499(1-2):74-84. Pubmedid: 11118640.
  • McMahon RJ, Hwang JB, Frost SC. Glucose deprivation does not affect GLUT1 targeting in 3T3-L1 adipocytes. Biochem Bioph Res Co. 2000 Jul;273(3):859-864. Pubmedid: 10891337.
  • Hwang JB, Frost SC. Effect of alternative glycosylation on insulin receptor processing. J Biol Chem. 1999 Aug;274(32):22813-22820. Pubmedid: 10428866.
  • Kitzman HH, McMahon RJ, Aslanian AM, Fadia PM, Frost SC. Differential regulation of GRP78 and GLUT1 expression in 3T3-L1 adipocytes. Mol Cell Biochem. 1996 Sep;162(1):51-58. Pubmedid: 8905625.
  • Fisher MD, Frost SC. Translocation of GLUT1 does not account for elevated glucose transport in glucose-deprived 3T3-L1 adipocytes. J Biol Chem. 1996 May;271(20):11806-11809. Pubmedid: 8662621.
  • McMahon RJ, Frost SC. Glycogen: a carbohydrate source for GLUT-1 glycosylation during glucose deprivation of 3T3-L1 adipocytes. Am J Physiol. 1996 Apr;270(4 Pt 1):E640-E645. Pubmedid: 8928771.
  • McMahon RJ, Frost SC. Nutrient control of GLUT1 processing and turnover in 3T3-L1 adipocytes. J Biol Chem. 1995 May;270(20):12094-12099. Pubmedid: 7744857.
  • Kitzman HH, McMahon RJ, Williams MG, Frost SC. Effect of glucose deprivation of GLUT 1 expression in 3T3-L1 adipocytes. J Biol Chem. 1993 Jan;268(2):1320-1325. Pubmedid: 7678253.
  • Frost SC, Hinchliffe JR. Retinoic acid effects on cell death and division patterns in experimental chick wing buds. Prog Clin Biol Res. 1993;383B:769-779. Pubmedid: 8115392.
  • Wong WT, Frost SC, Nick HS. Protein-synthesis-dependent induction of annexin I by glucocorticoid. Biochem J. 1991 Apr;275 ( Pt 2):313-319. Pubmedid: 1827255. Pmcid: PMC1150054.
  • Frost SC, Risch R. Role of receptor internalization in insulin signalling. Adv Exp Med Biol. 1991;293:215-225. Pubmedid: 1767732.
  • Staggers JE, Frost SC, Wells MA. Studies on fat digestion, absorption, and transport in the suckling rat. III. Composition of bile and evidence for enterohepatic circulation of bile salts. J Lipid Res. 1982 Nov;23(8):1143-1151. Pubmedid: 7175372.
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