Marilyn M. Bui, MD, PhD

Dr. Bui is passionate about translational research which identifies or validates diagnostic, prognostic and predictive biomarkers for cancer, especially for sarcoma and breast cancer, using methods of molecular, immunohistochemical and digital pathology.

• Soliman H, Rawal B, Fulp J, Lee JH, Lopez A, Bui MM, Khalil F, Antonia S, Yfantis HG, Lee DH, Dorsey TH, Ambs S. Analysis of indoleamine 2-3 dioxygenase (IDO1) expression in breast cancer tissue by immunohistochemistry. Cancer Immunol Immunother. 2013 May;62(5):829-837. Pubmedid: 23344392.
• Demicco EG, Wang WL, Madewell JE, Huang D, Bui MM, Bridge JA, Meis JM. Osseous myxochondroid sarcoma: a detailed study of 5 cases of extraskeletal myxoid chondrosarcoma of the bone. Am J Surg Pathol. 2013 May;37(5):752-762. Pubmedid: 23588370.
• Liu W, Bui MM, Cheong D, Caracciolo JT. Hibernoma: comparing imaging appearance with more commonly encountered benign or low-grade lipomatous neoplasms. Skeletal Radiol. 2013 Feb. Pubmedid: 23385517.
• Allam-Nandyala P, Bui MM, Deconti R, Purohit C, Altiok S. Squamous cell carcinoma with rhabdoid phenotype of skin/soft tissue in a transplant patient: An exceptional case and review of the literature. Diagn Cytopathol. 2013 Feb;41(2):159-163. Pubmedid: 23335454.
• Riddle ND, Bui MM. Fibrous dysplasia. Arch Pathol Lab Med. 2013 Jan;137(1):134-138. Pubmedid: 23276185.
• Fu W, Sharma SS, Ma L, Chu B, Bui MM, Reed D, Pledger WJ. Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor. Cell Death Dis. 2013;4:e566. Pubmedid: 23538447.
• Kreahling JM, Foroutan P, Reed D, Martinez G, Razabdouski T, Bui MM, Raghavan M, Letson D, Gillies RJ, Altiok S. Wee1 Inhibition by MK-1775 Leads to Tumor Inhibition and Enhances Efficacy of Gemcitabine in Human Sarcomas. PLoS One. 2013;8(3):e57523. Pubmedid: 23520471.
• Vohra NA, Turaga KK, Gonzalez RJ, Conley A, Reed D, Bui MM, Cheong D, Letson DG, Zager JS. The use of isolated limb infusion in limb threatening extremity sarcomas. Int J Hyperthermia. 2013;29(1):1-7. Pubmedid: 23205633.
• Koohbanani B, Han G, Reed D, Zhao Q, Yi D, Henderson-Jackson E, Bui MM. Ethnicity and age disparities in Ewing sarcoma outcome. Fetal Pediatr Pathol. 2012 Oct. Pubmedid: 23043418.
• Ibrahim-Hashim A, Cornnell HH, Abrahams D, Lloyd M, Bui M, Gillies RJ, Gatenby RA. Systemic Buffers Inhibit Carcinogenesis in TRAMP Mice. J Urol. 2012 Aug;188(2):624-631. Pubmedid: 22704445.
• von Mehren M, Benjamin RS, Bui MM, Casper ES, Conrad EU, Delaney TF, Ganjoo KN, George S, Gonzalez R, Heslin MJ, Kane JM, Mayerson J, McGarry SV, Meyer C, O'Donnell RJ, Paz B, Pfeifer JD, Pollock RE, Randall RL, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Shankar S, Van Tine BA, Wayne J, Sundar H, McMillian NR. Soft Tissue Sarcoma, Version 2.2012: Featured Updates to the NCCN Guidelines. J Natl Compr Canc Netw. 2012 Aug;10(8):951-960. Pubmedid: 22878820.
• Bai Y, Li J, Fang B, Edwards A, Zhang G, Bui M, Eschrich S, Altiok S, Koomen J, Haura EB. Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors. Cancer Res. 2012 May;72(10):2501-2511. Pubmedid: 22461510.
• Riddle ND, Bui MM. When melanoma is negative for S100: diagnostic pitfalls. Arch Pathol Lab Med. 2012 Mar;136(3):237-239. Pubmedid: 22372898.
• Finkelstein SE, Iclozan C, Bui MM, Cotter MJ, Ramakrishnan R, Ahmed J, Noyes DR, Cheong D, Gonzalez RJ, Heysek RV, Berman C, Lenox BC, Janssen W, Zager JS, Sondak VK, Letson GD, Antonia SJ, Gabrilovich DI. Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients. Int J Radiat Oncol Biol Phys. 2012 Feb;82(2):924-932. Pubmedid: 21398051.
• Kreahling JM, Gemmer JY, Reed D, Letson D, Bui M, Altiok S. MK1775, a Selective Wee1 Inhibitor, Shows Single-Agent Antitumor Activity against Sarcoma Cells. Mol Cancer Ther. 2012 Jan;11(1):174-182. Pubmedid: 22084170.
• Tafreshi NK, Bui MM, Bishop K, Lloyd MC, Enkemann SA, Lopez AS, Abrahams D, Carter WB, Vagner J, Gobmyer SR, Gillies RJ, Morse DL. Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes. Clin Cancer Res. 2012 Jan;18(1):207-219. Pubmedid: 22016510.
• Bardhan P, Bui MM, Minton S, Loftus L, Carter WB, Laronga C, Ismail-Khan R. HER2-positive male breast cancer with thyroid cancer: an institutional report and review of literature. Ann Clin Lab Sci. 2012;42(2):135-139. Pubmedid: 22585608.
• Seifert RP, McNab P, Sexton WJ, Sawczyn KK, Smith P, Coppola D, Bui MM. Rhabdomyomatous differentiation in wilms tumor pulmonary metastases: a case report and literature review. Ann Clin Lab Sci. 2012;42(4):409-416. Pubmedid: 23090738.
• Riddle ND, Gonzalez RJ, Bridge JA, Antonia S, Bui MM. A CD117 and CD34 immunoreactive sarcoma masquerading as a gastrointestinal stromal tumor: diagnostic pitfalls of ancillary studies in sarcoma. Cancer Control. 2011 Jul;18(3):152-159. Pubmedid: 21666577.
• Fu W, Ma L, Chu B, Wang X, Bui MM, Gemmer J, Altiok S, Pledger WJ. The Cyclin-Dependent Kinase Inhibitor SCH 727965 (Dinacliclib) Induces the Apoptosis of Osteosarcoma Cells. Mol Cancer Ther. 2011 Jun;10(6):1018-1027. Pubmedid: 21490307.
• Zhang X, Bui MM, Caracciolo J, Field TL, Zhang L. Adult anaplastic large cell lymphoma involving the central nervous system: a rare clinical scenario. Ann Hematol. 2011 Jun;90(6):721-723. Pubmedid: 20838823.
• Nasir A, Helm J, Turner L, Chen DT, Strosberg J, Hafez N, Henderson-Jackson EB, Hodul P, Bui MM, Nasir NA, Hakam A, Malafa MP, Yeatman TJ, Coppola D, Kvols LK. RUNX1T1: a novel predictor of liver metastasis in primary pancreatic endocrine neoplasms. Pancreas. 2011 May;40(4):627-633. Pubmedid: 21499216.
• Tafreshi NK, Enkemann SA, Bui MM, Lloyd MC, Abrahams D, Huynh AS, Kim J, Grobmyer SR, Carter WB, Vagner J, Gillies RJ, Morse DL. A mammaglobin-A targeting agent for noninvasive detection of breast cancer metastasis in lymph nodes. Cancer Res. 2011 Feb;71(3):1050-1059. Pubmedid: 21169406.
• Shackelford RE, Allam-Nandyala P, Bui MM, Kiluk JV, Esposito NN. Primary colorectal adenocarcinoma metastatic to the breast: case report and review of nineteen cases. Case Rep Med. 2011;2011:738413. Pubmedid: 21738536. Pmcid: PMC3123911.
• Bui MM, Han G, Acs G, Reed D, Gonzalez RJ, Pasha TL, Zhang PJ. Connexin 43 is a potential prognostic biomarker for ewing sarcoma/primitive neuroectodermal tumor. Sarcoma. 2011;2011:971050. Pubmedid: 21647307. Pmcid: PMC3103998.
• Henderson-Jackson EB, Helm J, Ghayouri M, Hakam A, Nasir A, Leon M, Bui M, Yeatman T, Coppola D. Correlation between Mcl-1 and pAKT protein expression in colorectal cancer. Int J Clin Exp Pathol. 2010 Oct;3(8):768-774. Pubmedid: 21151390. Pmcid: PMC2993227.
• Bui MM, Purohit CN, Hakam A. Fine needle aspiration biopsy of an osteoclast-rich undifferentiated urothelial carcinoma: A cytology case report and review of the literature. Cytojournal. 2010 Sep;7:18. Pubmedid: 20976205.
• Chen Y, Gruidl M, Remily-Wood E, Liu RZ, Eschrich S, Lloyd M, Nasir A, Bui MM, Huang E, Shibata D, Yeatman T, Koomen JM. Quantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry. J Proteome Res. 2010 Aug;9(8):4215-4227. Pubmedid: 20590165. Pmcid: PMC2924816.
• Farma JM, Ammori JB, Zager JS, Marzban SS, Bui MM, Bichakjian CK, Johnson TM, Lowe L, Sabel MS, Wong SL, Letson GD, Messina JL, Cimmino VM, Sondak VK. Dermatofibrosarcoma protuberans: how wide should we resect?. Ann Surg Oncol. 2010 Aug;17(8):2112-2118. Pubmedid: 20354798.
• Bui MM, Draper NL, Dessureault S, Nasir NA, Cooper H, Nasir A, Coppola D. Colonic angiolymphoid hyperplasia with eosinophilia masquerading as malignancy: a case report and review of the literature. Clin Colorectal Cancer. 2010 Jul;9(3):179-182. Pubmedid: 20643624.
• Rusthoven C, Shames ML, Bui MM, Gonzalez RJ. High-grade undifferentiated pleomorphic sarcoma of the aortic arch: a case of endovascular therapy for embolic prophylaxis and review of the literature. Vasc Endovascular Surg. 2010 Jul;44(5):385-391. Pubmedid: 20538733.
• Ismail-Khan R, Bui MM. A review of triple-negative breast cancer. Cancer Control. 2010 Jul;17(3):173-176. Pubmedid: 20664514.
• Demetri GD, Antonia S, Benjamin RS, Bui MM, Casper ES, Conrad EU, DeLaney TF, Ganjoo KN, Heslin MJ, Hutchinson RJ, Kane JM, Letson GD, McGarry SV, O'Donnell RJ, Paz IB, Pfeifer JD, Pollock RE, Randall RL, Riedel RF, Schupak KD, Schwartz HS, Thornton K, von Mehren M, Wayne J. Soft tissue sarcoma. J Natl Compr Canc Netw. 2010 Jun;8(6):630-674. Pubmedid: 20581298.
• Naghashpour M, Cualing HD, Szabunio M, Bui MM. Hyaline-vascular castleman disease: a rare cause of solitary subcutaneous soft tissue mass. Am J Dermatopathol. 2010 May;32(3):293-297. Pubmedid: 20098298.
• Allam-Nandyala P, Bui MM, Caracciolo JT, Hakam A. Squamous cell carcinoma and osteosarcoma arising from a dermoid cyst--a case report and review of literature. Int J Clin Exp Pathol. 2010 Jan;3(3):313-318. Pubmedid: 20224730. Pmcid: PMC2836509.
• Riddle ND, Yamauchi H, Caracciolo JT, Cheong D, Khakpour N, Bui MM. Giant cell tumor of the anterior rib masquerading as a breast mass: a case report and review of current literature. Cases J. 2010;3:51. Pubmedid: 20205847. Pmcid: PMC2825505.
• Riddle ND, Quigley BC, Browarsky I, Bui MM. Leiomyosarcoma arising in the pancreatic duct: a case report and review of the current literature. Case Rep Med. 2010;2010:252364. Pubmedid: 20589089. Pmcid: PMC2892659.
• Shackelford RE, Bui MM, Coppola D, Hakam A. Over-expression of nicotinamide phosphoribosyltransferase in ovarian cancers. Int J Clin Exp Pathol. 2010;3(5):522-527. Pubmedid: 20606733. Pmcid: PMC2897104.
• Lloyd MC, Allam-Nandyala P, Purohit CN, Burke N, Coppola D, Bui MM. Using image analysis as a tool for assessment of prognostic and predictive biomarkers for breast cancer: How reliable is it?. J Pathol Inform. 2010;1:29. Pubmedid: 21221174. Pmcid: PMC3017682.
• Bui MM, Zheng Z, Antonia S, Bepler G. Thymidylate synthase 1 (TS1) in-situ protein expression predicts the survival of Ewing/PNET. Fetal Pediatr Pathol. 2010;29(6):385-392. Pubmedid: 21043562. Pmcid: PMC3568950.
• Riddle ND, Bowers JW, Bui MM, Morgan MB. Primary cutaneous osteoblastic osteosarcoma: a case report and review of the current literature. Clin Exp Dermatol. 2009 Dec;34(8):e879-e880. Pubmedid: 20055854.
• Alexander GE, Henderson ER, Rodriguez AR, Bui MM, Cheong D, Letson GD. Extraskeletal myxoid chondrosarcoma: rare presentation in the knee joint space. Orthopedics. 2009 Dec;32(12):919. Pubmedid: 19968226.
• Yasuda T, Perry KD, Nelson M, Bui MM, Nasir A, Goldschmidt R, Gnepp DR, Bridge JA. Alveolar rhabdomyosarcoma of the head and neck region in older adults: genetic characterization and a review of the literature. Hum Pathol. 2009 Mar;40(3):341-348. Pubmedid: 18973919. Pmcid: PMC2753286.
• Schlauder SM, Knapp C, Steffensen TS, Bui MM. Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma. Fetal Pediatr Pathol. 2009;28(5):232-238. Pubmedid: 19842877.
• McNab PM, DeMers NM, Schlauder S, Morgan M, Nasir A, Coppola D, Bui MM. Potential utility of CD5 immunohistochemical staining in the diagnosis of muscle tumors. Ann Clin Lab Sci. 2009;39(2):108-113. Pubmedid: 19429795.
• DeMers Riddle NM, Schlauder SM, Bui MM. Immunostatin patterns of HER-2, EGFR, and CD117 in fibrous dysplasia: a six case series and literature review. J Orthop. 2009;6(2):e4-e4.
• Draper N, Bui M, Boulware DC, Lloyd M, Chiappori AA, Pledger WJ, Coppola D. Increased cyclin D3 expression significantly correlates with p27 nuclear positivity in gastrointestinal stromal tumors. Hum Pathol. 2008 Dec;39(12):1784-1791. Pubmedid: 18701138.
• Zager J, Bui M, Farma J, Messina J, Sondak V. Proper margins of excision in dermatofibrosarcoma protuberans: wide or narrow?. Ann Surg Oncol. 2008 Sep;15(9):2614-2616. Pubmedid: 18452044.
• Cheng P, Corzo CA, Luetteke N, Yu B, Nagaraj S, Bui MM, Ortiz M, Nacken W, Sorg C, Vogl T, Roth J, Gabrilovich DI. Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med. 2008 Sep;205(10):2235-2249. Pubmedid: 18809714.
• Bui M, Smith P, Agresta S, Cheong D, Letson G. Practical issues of intraoperative frozen section diagnosis of bone and soft tissue lesions. Cancer Control. 2008 Jan;15(1):7-12. Pubmedid: 18094656.
• Schlauder SM, Steffensen TS, Morgan M, Letson DG, Pledger WJ, Ma L, Bui MM. Assessment of muscarinic and nicotinic acetylcholine receptor expression in primitive neuroectodermal tumor/ewing family of tumor and desmoplastic small round cell tumor: an immunohistochemical and Western blot study of tissue microarray and cell lines. Fetal Pediatr Pathol. 2008;27(2):83-97. Pubmedid: 18568996.
• Steffensen T, Gilbert-Barness E, Wagoner M, Bui M, Browarsky I. Human chorionic gonadotrophin producing epithelioid sarcoma metastatic to the placenta. Fetal Pediatr Pathol. 2008;27(6):282-291. Pubmedid: 19065326.
• Bui MM, Bagui TK, Boulware DC, Letson DG, Nasir A, Kaiser HE, Pledger WJ, Coppola D. Altered expression of cell cycle regulatory proteins in benign and malignant bone and soft tissue neoplasms. In Vivo. 2007 Sep;21(5):729-737. Pubmedid: 18019405.
• Dorfman DM, Bui MM, Tubbs RR, Hsi ED, Fitzgibbons PL, Linden MD, Rickert RR, Roche PC. The CD117 immunohistochemistry tissue microarray survey for quality assurance and interlaboratory comparison: a College of American Pathologists Cell Markers Committee Study. Arch Pathol Lab Med. 2006 Jun;130(6):779-782. Pubmedid: 16740027.
• Khalbuss W, Bui M, Loya A. A 19-year-old woman with a cervicovaginal mass and elevated serum CA 125.Desmoplastic small round cell tumor. Arch Pathol Lab Med. 2006 Apr;130(4):e59-e61. Pubmedid: 16594762.
• Bui M, Khalbuss WE. Primary small cell neuroendocrine carcinoma of the urinary bladder with coexisting high-grade urothelial carcinoma: a case report and a review of the literature. Cytojournal. 2005 Nov;2:18-18. Pubmedid: 16269089.
• Khalbuss W, Grigorian S, Bui M, Elhosseiny A. Small-cell tumors of the liver: a cytological study of 91 cases and a review of the literature. Diagn Cytopathol. 2005 Jul;33(1):8-14. Pubmedid: 15945087.
• Lu D, Masood S, Khalbuss W, Bui M. A subset of breast invasive ductal carcinoma with distinctive cytomorphology, aggressive clinical behavior, and unique immunologic profiles. Cancer. 2002 Oct;96(5):294-300. Pubmedid: 12378597.
• Masood S, Bui M. Prognostic and predictive value of HER2/neu oncogene in breast cancer. Microsc Res Tech. 2002 Oct;59(2):102-108. Pubmedid: 12373720.
• Yu M, Bui M, Gulati P, Masood S. Lipogranuloma. Breast J. 2001 Sep;7(5):363-364. Pubmedid: 11906448.
• Yu M, Bui M, Bridges M, Masood S. Papillary carcinoma. Breast J. 2001 Jan;7(1):68-69. Pubmedid: 11348420.
• Masood S, Bui M. Assessment of Her-2/neu overexpression in primary breast cancers and their metastatic lesions: an immunohistochemical study. Ann Clin Lab Sci. 2000 Jul;30(3):259-265. Pubmedid: 10945565.
• Persons D, Bui M, Lowery M, Mark H, Yung J, Birkmeier J, Wong E, YangSJ, Masood S. Fluorescence in situ hybridization (FISH) for detection of HER-2/neu amplification in breast cancer: a multicenter portability study. Ann Clin Lab Sci. 2000 Jan;30(1):41-48. Pubmedid: 10678582.
• Amornmarn R, Bui M, Prempree T, Masood S. Molecular predictive factors for local recurrence and distant metastasis of breast cancer after lumpectomy with postoperative radiation therapy. Ann Clin Lab Sci. 2000 Jan;30(1):33-40. Pubmedid: 10678581.
• Amornmarn R, Prempree T, Bui MM, Masood S. p53 mutation and MDR1 overexpression in local and distant failures of breast cancer treated by lumpectomy and radiation. Thai J Surg. 1999;20(1):1-8.
• Masood S, Bui M, Lu L. Comparison of proliferation activity in breast carcinoma by flow cytomet analysis of S-phase and quantitative analysis of MIB-1. Ann Clin Lab Sci. 1998 Nov;28(6):315-323. Pubmedid: 9846198 .
• Masood S, Bui M, Yung J, Mark H, Wong E, Birkmeier J, Yang S, Hsu P. Reproducibility of LSI HER-2/neu SpectrumOrange and CEP 17 SpectrumGreen Dual Color deoxyribonucleic acid probe kit. Ann Clin Lab Sci. 1998 Jul;28(4):215-223. Pubmedid: 9715348 .
• Masood S, Bui M, Kublius P, Slovak M. Cytogenetic abnormalities of primary breast carcinoma: comparative analysis of fluorescence in situ hybridization (FISH) and flow cytometry. Breast J. 1998;4(2):89-95. Pubmedid: NoPMID.
• Bui M, Luo D, She J, Maclaren N, Muir A, Thomson G, She J. Paternally transmitted IDDM2 influences diabetes susceptibility despite biallelic expression of the insulin gene in human pancreas. J Autoimmun. 1996 Feb;9(1):97-103. Pubmedid: 8845059 .
• Bui M, Jenkins S. Clinical infectious disease testing by amplification technology. Jacksonville Medicine. 1996;47(6):247-250. Pubmedid: NoPMID.
• Luo D, Bui M, Muir A, Maclaren N, Thomson G, She J. Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am J Hum Genet. 1995 Oct;57(4):911-919. Pubmedid: 7573053 .
• She J, Bui M, Tian X, Muir A, Wakeland E, Zorovich B, Zhang L, Liu M, Thomson G, Maclaren N. Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes. Autoimmunity. 1994;18(3):195-203. Pubmedid: 7858104 .
• Henderson-Jackson E, Sexton W, Zhang J, Hakam A, Petrovskyy VS, Bui MM, Chuang ST. Cystic prostatic ductal adenocarcinoma: an unusual presentation and cytological diagnosis. Ann Clin Lab Sci. 2012 Winter;42(1):81-88. Pubmedid: 22371914.
• Moody P, Bui MM, Vrionis F, Setzer M, Rojiani AM. Synovial chondromatosis of spine: case report and review of the literature. Ann Clin Lab Sci. 2010 Winter;40(1):71-74. Pubmedid: 20124333.