Eric K. Outwater, MD

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Eric K. Outwater, MD

Senior Member

Office  (813) 745-6187

Education And Training
  • Fellow, Hospital of the University of Pennsylvania Devon MRI Center, 1992 - Body MRI
  • Resident, Tufts New England Medical Center, 1990 - Radiology
  • Intern, Mount Sinai Hospital, 1986 - Medicine
  • MD, University of California, San Diego, 1985
  • BS, University of Michigan, 1979 - Zoology


His research interests are primarily in genitourinary and gynecologic MRI. He has been the primary facilitator of physician education in RECIST measurements in the department and serves as medical director for the Image Response Assessment Team (IRAT) Core facility.  He has been instrumental in securing funding for the IRAT for clinical trials using tumor metrics at Moffitt.

  • Outwater EK, Montilla-Soler JL. Imaging of prostate carcinoma. Cancer Control. 2013 Jul;20(3):161-176. Pubmedid: 23811700.
  • Outwater EK. Imaging of the liver for hepatocellular cancer. Cancer Control. 2010 Apr;17(1):72-82. Pubmedid: 20404790.
  • Li Z, Graff C, Gmitro AF, Squire SW, Bilgin A, Outwater EK, Altbach MI. Rapid water and lipid imaging with T2 mapping using a radial IDEAL-GRASE technique. Magn Reson Med. 2009 Jun;61(6):1415-1424. Pubmedid: 19353651. Pmcid: PMC2747511.
  • Knowles NG, Smith DL, Outwater EK. MRI diagnosis of brown tumor based on magnetic susceptibility. J Magn Reson Imaging. 2008 Sep;28(3):759-761. Pubmedid: 18777537.
  • Chen Z, Wang Z, Lohman T, Heymsfield SB, Outwater E, Nicholas JS, Bassford T, LaCroix A, Sherrill D, Punyanitya M, Wu G, Going S. Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older women. J Nutr. 2007 Dec;137(12):2775-2780. Pubmedid: 18029498.
  • Gigena M, Villar HV, Knowles NG, Cunningham JT, Outwater EK, Leon LR. Antegrade bowel intussusception after remote Whipple and Puestow procedures for treatment of pancreas divisum. World J Gastroenterol. 2007 Nov;13(44):5954-5956. Pubmedid: 17990363.
  • Shin SL, Outwater EK. Benign large cell calcifying Sertoli cell tumor of the testis in a prepubescent patient. AJR Am J Roentgenol. 2007 Aug;189(2):W65-W66. Pubmedid: 17646440.
  • Erly WK, Oh ES, Outwater EK. The utility of in-phase/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine. AJNR Am J Neuroradiol. 2006 June;27(6):1183-1188. Pubmedid: 16775260.
  • Saini S, Sharma R, Baron RL, Turner DA, Ros PR, Hahn PF, Small WC, Delange EE, Stillman AE, Edelman RR, Runge VM, Outwater EK. Multicentre dose-ranging study on the efficacy of USPIO ferumoxtran-10 for liver MR imaging. Clin Radiol. 2000 Sep;55(9):690-695. Pubmedid: 10988047.
  • Halpern EJ, Mitchell DG, Wechsler RJ, Outwater EK, Moritz MJ, Wilson GA. Preoperative evaluation of living renal donors: comparison of CT angiography and MR angiography. Radiology. 2000 Aug;216(2):434-439. Pubmedid: 10924566.
  • Blasbalg R, Mitchell DG, Outwater EK, Ito K, Gabata T, Chiowanich P. Free MRA of the abdomen: postprocessing dynamic gadolinium-enhanced 3D axial MR images. Abdom Imaging. 2000;25(1):62-66. Pubmedid: 10652925.
  • Hussain SM, Outwater EK, Siegelman ES. Mucinous versus nonmucinous rectal carcinomas: differentiation with MR imaging. Radiology. 1999 Oct;213(1):79-85. Pubmedid: 10540644.
  • Nguyen BC, Stanford W, Thompson BH, Rossi NP, Kernstine KH, Kern JA, Robinson RA, Amorosa JK, Mammone JF, Outwater EK. Multicenter clinical trial of ultrasmall superparamagnetic iron oxide in the evaluation of mediastinal lymph nodes in patients with primary lung carcinoma. J Magn Reson Imaging. 1999 Sep;10(3):468-473. Pubmedid: 10508310.
  • Johnson PT, Outwater EK. Pancreatic carcinoma versus chronic pancreatitis: dynamic MR imaging. Radiology. 1999 Jul;212(1):213-218. Pubmedid: 10405744.
  • Small WC, DeSimone-Macchi D, Parker JR, Sukerkar A, Hahn PF, Rubin DL, Zelch JV, Kuhlman JE, Outwater EK, Weinreb JC, Brown JJ, de Lange EE, Woodward PJ, Arildsen R, Foster GS, Runge VM, Aisen AM, Muroff LR, Thoeni RF, Parisky YR, Tanenbaum LN, Totterman S, Herfkens RJ, Knudsen J, Bernardino ME. A multisite phase III study of the safety and efficacy of a new manganese chloride-based gastrointestinal contrast agent for MRI of the abdomen and pelvis. J Magn Reson Imaging. 1999 Jul;10(1):15-24. Pubmedid: 10398973.
  • Ito K, Mitchell DG, Outwater EK, Blasbalg R. Primary sclerosing cholangitis: MR imaging features. Ajr Am J Roentgenol. 1999 Jun;172(6):1527-1533. Pubmedid: 10350284.
  • Outwater EK. Ultrafast MR imaging of the pelvis. Eur J Radiol. 1999 Mar;29(3):233-244. Pubmedid: 10399609.
  • Outwater EK, Marchetto BE, Wagner BJ, Siegelman ES. Aggressive angiomyxoma: findings on CT and MR imaging. Ajr Am J Roentgenol. 1999 Feb;172(2):435-438. Pubmedid: 9930798.
  • Sharma R, Saini S, Ros PR, Hahn PF, Small WC, de Lange EE, Stillman AE, Edelman RR, Runge VM, Outwater EK, Morris M, Lucas M. Safety profile of ultrasmall superparamagnetic iron oxide ferumoxtran-10: phase II clinical trial data. J Magn Reson Imaging. 1999 Feb;9(2):291-294. Pubmedid: 10077027.
  • Kainz G, Mammone J, Outwater EK. Change in the composition of adrenal nodules after therapy as revealed by opposed-phase MR imaging. Ajr Am J Roentgenol. 1997 Aug;169(2):549-550. Pubmedid: 9242774.
  • Rubin DL, Falk KL, Sperling MJ, Ross M, Saini S, Rothman B, Shellock F, Zerhouni E, Stark D, Outwater EK, Schmiedl U, Kirby LC, Chezmar J, Coates T, Chang M, Silverman JM, Rofsky N, Burnett K, Engel J, Young SW. A multicenter clinical trial of Gadolite Oral Suspension as a contrast agent for MRI. J Magn Reson Imaging. 1997;7(5):865-872. Pubmedid: 9307913.
  • Kelekis NL, Semelka RC, Siegelman ES, Ascher SM, Outwater EK, Woosley JT, Reinhold C, Mitchell DG. Focal hepatic lymphoma: magnetic resonance demonstration using current techniques including gadolinium enhancement. Magn Reson Imaging. 1997;15(6):625-636. Pubmedid: 9285802.
  • Outwater EK, Mitchell DG. Normal ovaries and functional cysts: MR appearance. Radiology. 1996 Feb;198(2):397-402. Pubmedid: 8596839.
  • Mitchell DG, Stolpen AH, Siegelman ES, Bolinger L, Outwater EK. Fatty tissue on opposed-phase MR images: paradoxical suppression of signal intensity by paramagnetic contrast agents. Radiology. 1996 Feb;198(2):351-357. Pubmedid: 8596831.
  • Outwater EK. Contrast-enhanced MR imaging of gynecologic disorders. Magn Reson Imaging Clin N Am. 1996 Feb;4(1):133-151. Pubmedid: 8673711.
  • Mitchell DG, Outwater EK, Matteucci T, Rubin DL, Chezmar JL, Saini S. Adrenal gland enhancement at MR imaging with Mn-DPDP. Radiology. 1995 Mar;194(3):783-787. Pubmedid: 7862979.
  • Outwater EK, Mitchell DG. Magnetic resonance imaging techniques in the pelvis. Magn Reson Imaging Clin N Am. 1994 May;2(2):161-188. Pubmedid: 7489284.
  • Méndez RJ, Schiebler ML, Outwater EK, Kressel HY. Hepatic abscesses: MR imaging findings. Radiology. 1994 Feb;190(2):431-436. Pubmedid: 8284394.
  • Dravid VS, Shapiro MJ, Mitchell DG, Outwater EK, Piccoli CW, Feld RI, Wechsler RJ, Rosato FE. MR portography: preliminary comparison with CT portography and conventional MR imaging. J Magn Reson Imaging. 1994;4(6):767-771. Pubmedid: 7865935.
  • Abbas YA, Kressel HY, Wehrli FW, Gefter WB, Dinsmore BJ, Chan TW, Oleaga L, Milestone BN, Outwater EK. Differential diagnosis of hepatic neoplasms: spin echo versus gadolinium-diethylenetriaminepentaacetate-enhanced gradient echo imaging. Magn Reson Q. 1991 Oct;7(4):275-292. Pubmedid: 1790113.
  • Raman SS, Leary C, Bluemke DA, Amendola M, Sahani D, McTavish JD, Brody J, Outwater E, Mitchell D, Sheafor DH, Fidler J, Francis IR, Semelka RC, Shamsi K, Gschwend S, Feldman DR, Breuer J. Improved characterization of focal liver lesions with liver-specific gadoxetic acid disodium-enhanced magnetic resonance imaging: a multicenter phase 3 clinical trial. J Comput Assist Tomogr. 34(2):163-172. Pubmedid: 20351497. Pmcid: PMC3036163.
  • Outwater EK, Ito K, Siegelman E, Martin CE, Bhatia M, Mitchell DG. Rapidly enhancing hepatic hemangiomas at MRI: distinction from malignancies with T2-weighted images. J Magn Reson Imaging. 7(6):1033-1039. Pubmedid: 9400846.
  • Outwater EK, Huang AB, Dunton CJ, Talerman A, Capuzzi DM. Papillary projections in ovarian neoplasms: appearance on MRI. J Magn Reson Imaging. 7(4):689-695. Pubmedid: 9243390.
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