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David J. Drobes, PhD

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David J. Drobes, PhD

Senior Member

"Dr. Drobes long term goal is to improve upon the efficacy and dissemination of existing clinical treatments for tobacco and drug addiction."

Office  (813) 745-1751

Education And Training
  • PhD, Purdue University, 1993 - Clinical Psychology
  • MS, Purdue University, 1987 - Psychology
  • BS, State University of New York at Albany, 1984 - Psychology


Dr. Drobes’ research program addresses cancer prevention through developing an improved understanding of risk factors and interventions for tobacco use and dependence. His work generally encompasses a broad perspective toward addictive behaviors, with a focus on genetic and environmental influences on nicotine/tobacco use, nicotine withdrawal, and combined tobacco/alcohol use. Recent studies have examined potential endophenotypes that may be associated with specific molecular risk factors for nicotine use and withdrawal, including genotypes associated with reward-related and cognitive neural processes. In a more applied vein, his laboratory is examining brief smoking cessation interventions, including the use of physical activity to control cognitive and affective disturbances during nicotine withdrawal. Current methodologies include cognitive and psychophysiological cue reactivity paradigms, event-related brain potential recordings, and measurement of smoking behavior via observational and smoking topography recording. The long-term goal of this research is to translate basic laboratory findings into improved smoking cessation treatments.

  • Unrod M, Drobes DJ, Stasiewicz PR, Ditre JW, Heckman B, Miller RR, Sutton SK, Brandon TH. Decline in cue-provoked craving during cue exposure therapy for smoking cessation. Nicotine Tob Res. 2014 Mar;16(3):306-315. Pubmedid: 24078760.
  • Macqueen DA, Heckman BW, Blank MD, Janse Van Rensburg K, Park JY, Drobes DJ, Evans DE. Variation in the α 5 nicotinic acetylcholine receptor subunit gene predicts cigarette smoking intensity as a function of nicotine content. Pharmacogenomics J. 2014 Feb;14(1):70-76. Pubmedid: 23358500. Pmcid: PMC3778124.
  • Correa JB, Heckman BW, Marquinez NS, Drobes DJ, Unrod M, Roetzheim RG, Brandon TH. Perceived Medication Assignment during a Placebo-Controlled Laboratory Study of Varenicline: Temporal Associations of Treatment Expectancies with Smoking-Related Outcomes. Psychopharmacology (Berl). 2014 Jan. Pubmedid: 24408212.
  • Heckman BW, Kovacs MA, Marquinez NS, Meltzer LR, Tsambarlis ME, Drobes DJ, Brandon TH. Influence of affective manipulations on cigarette craving: a meta-analysis. Addiction. 2013 Dec;108(12):2068-2078. Pubmedid: 23795674. Pmcid: PMC3830730.
  • Evans DE, Maxfield ND, Van Rensburg KJ, Oliver JA, Jentink KG, Drobes DJ. Nicotine deprivation influences p300 markers of cognitive control. Neuropsychopharmacology. 2013 Nov;38(12):2525-2531. Pubmedid: 23807239. Pmcid: PMC3799074.
  • Oliver JA, Blank MD, Van Rensburg KJ, Macqueen DA, Brandon TH, Drobes DJ. Nicotine interactions with low-dose alcohol: Pharmacological influences on smoking and drinking motivation. J Abnorm Psychol. 2013 Nov;122(4):1154-1165. Pubmedid: 24364618.
  • Bloom EL, Potts GF, Evans DE, Drobes DJ. Cue reactivity in smokers: An event-related potential study. Int J Psychophysiol. 2013 Nov;90(2):258-264. Pubmedid: 23958866.
  • Janse Van Rensburg K, Elibero A, Kilpatrick M, Drobes DJ. Impact of aerobic exercise intensity on craving and reactivity to smoking cues. Exp Clin Psychopharmacol. 2013 Jun;21(3):196-203. Pubmedid: 23750690.
  • Oliver JA, Drobes DJ. Visual search and attentional bias for smoking cues: the role of familiarity. Exp Clin Psychopharmacol. 2013 May;20(6):489-496. Pubmedid: 22889041.
  • Drobes DJ, Macqueen DA, Blank MD, Saladin ME, Malcolm RJ. Effects of intravenous nicotine on prepulse inhibition in smokers and non-smokers: relationship with familial smoking. Psychopharmacology (Berl). 2013 Apr;229(2):285-294. Pubmedid: 23624809.
  • Macqueen DA, Heckman BW, Blank MD, Janse Van Rensburg K, Evans DE, Drobes DJ. Transient compensatory smoking in response to placebo cigarettes. Psychopharmacology (Berl). 2012 Sep;223(1):47-54. Pubmedid: 22427021. Pmcid: PMC3802524.
  • Ditre JW, Oliver JA, Myrick H, Henderson S, Saladin ME, Drobes DJ. Effects of divalproex on smoking cue reactivity and cessation outcomes among smokers achieving initial abstinence. Exp Clin Psychopharmac. 2012 Aug;20(4):293-301. Pubmedid: 22468897.
  • Braun AR, Heinz AJ, Veilleux JC, Conrad M, Weber S, Wardle M, Greenstein J, Evatt D, Drobes D, Kassel JD. The separate and combined effects of alcohol and nicotine on anticipatory anxiety: a multidimensional analysis. Addict Behav. 2012 Apr;37(4):485-491. Pubmedid: 22260966.
  • Hormes JM, Coffey SF, Drobes DJ, Saladin ME. The Obsessive Compulsive Cocaine Use Scale: development and initial validation of a self-rated instrument for the quantification of thoughts about cocaine use. Drug Alcohol Depend. 2012 Jan;120(1-3):250-254. Pubmedid: 21890282. Pmcid: PMC3245789.
  • Brandon TH, Drobes DJ, Unrod M, Heckman BW, Oliver JA, Roetzheim RC, Karver SB, Small BJ. Varenicline effects on craving, cue reactivity, and smoking reward. Psychopharmacology (Berl). 2011 Nov;218(2):391-403. Pubmedid: 21559801.
  • Elibero A, Janse Van Rensburg K, Drobes DJ. Acute effects of aerobic exercise and hatha yoga on craving to smoke. Nicotine Tob Res. 2011 Nov;13(11):1140-1148. Pubmedid: 21849414.
  • Thomas SE, Randall PK, Brady K, See RE, Drobes DJ. An acute psychosocial stressor does not potentiate alcohol cue reactivity in non-treatment-seeking alcoholics. Alcohol Clin Exp Res. 2011 Mar;35(3):464-473. Pubmedid: 21143244. Pmcid: PMC3117919.
  • Evans DE, Craig C, Oliver JA, Drobes DJ. The Smoking N-Back: A Measure of Biased Cue Processing at Varying Levels of Cognitive Load. Nicotine Tob Res. 2011 Feb;13(2):88-93. Pubmedid: 21127029.
  • Hitsman B, Shen BJ, Cohen RA, Morissette SB, Drobes DJ, Spring B, Schneider K, Evans DE, Gulliver SB, Kamholz BW, Price LH, Niaura R. Measuring smoking-related preoccupation and compulsive drive: evaluation of the obsessive compulsive smoking scale. Psychopharmacology (Berl). 2010 Sep;211(4):377-387. Pubmedid: 20582399. Pmcid: PMC2908436.
  • Connolly KM, Coffey SF, Baschnagel JS, Drobes DJ, Saladin ME. Evaluation of the Alcohol Craving Questionnaire-Now factor structures: application of a cue reactivity paradigm. Drug Alcohol Depend. 2009 Sep;103(1-2):84-91. Pubmedid: 19423243. Pmcid: PMC2751634.
  • Mason BJ, Light JM, Williams LD, Drobes DJ. Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin. Addict Biol. 2009 Apr;14(1):73-83. Pubmedid: 18855801. Pmcid: PMC2758315.
  • Rash CJ, Coffey SF, Baschnagel JS, Drobes DJ, Saladin ME. Psychometric properties of the IES-R in traumatized substance dependent individuals with and without PTSD. Addict Behav. 2009 Mar;33(8):1039-1047. Pubmedid: 18501524. Pmcid: PMC2494706.
  • Evans DE, Park JY, Maxfield N, Drobes DJ. Neurocognitive variation in smoking behavior and withdrawal: genetic and affective moderators. Genes Brain Behav. 2009 Feb;8(1):86-96. Pubmedid: 19220487.
  • Drobes DJ, Carter AC, Goldman MS. Alcohol expectancies and reactivity to alcohol-related and affective cues. Exp Clin Psychopharmac. 2009 Feb;17(1):1-9. Pubmedid: 19186929.
  • Mason BJ, Light JM, Escher T, Drobes DJ. Effect of positive and negative affective stimuli and beverage cues on measures of craving in non treatment-seeking alcoholics. Psychopharmacology (Berl). 2009 Jan;200(1):141-150. Pubmedid: 18604601. Pmcid: PMC2758314.
  • Evans D, Drobes D. Nicotine self-medication of cognitive-attentional processing. Addict Biol. 2009 Jan;14(1):32-42. Pubmedid: 18855804.
  • Baschnagel J, Coffey S, Schumacher J, Drobes D, Saladin M. Relationship between PTSD symptomatology and nicotine dependence severity in crime victims. Addict Behav. 2008 Nov;33(11):1441-1447. Pubmedid: 18442884.
  • Lopez E, Drobes D, Thompson J, Brandon T. Effects of a body image challenge on smoking motivation among college females. Health Psychol. 2008 May;27(3 Suppl):S243-S251. Pubmedid: 18979977.
  • Drobes D, Elibero A, Evans D. Attentional bias for smoking and affective stimuli: a stroop task study. Psychol Addict Behav. 2006 Dec;20(4):490-495. Pubmedid: 17176185.
  • Hendricks P, Ditre J, Drobes D, Brandon T. The early time course of smoking withdrawal effects. Psychopharmacology (Berl). 2006 Aug;187(3):385-396. Pubmedid: 16752139.
  • Hendricks P, Ditre J, Drobes D, Brandon T. The early time course of smoking withdrawal effects. Psychopharmacology (Berl). 2006 Aug;187(3):385-96. Pubmedid: 16752139.
  • Upadhyaya H, Drobes D, Wang W. Reactivity to in vivo smoking cues in older adolescent cigarette smokers. Nicotine Tob Res. 2006 Feb;8(1):135-140. Pubmedid: 16497607.
  • Thomas S, Drobes D, Deas D. Alcohol cue reactivity in alcohol-dependent adolescents. J Stud Alcohol. 2005 May;66(3):354-360. Pubmedid: 16047524.
  • Drobes D, Munafo M, Leigh F, Saladin M. A family smoking index to capture genetic influence in smoking: rationale and two validation studies. Nicotine Tob Res. 2005 Feb;7(1):41-46. Pubmedid: 15804676.
  • Colby S, Drobes D, West R. International advances in nicotine and tobacco research. Nicotine Tob Res. 2005;7(4):667-709. Pubmedid: 16085535.
  • Drobes DJ, Anton RF, Thomas SE, Voronin K. Effects of naltrexone and nalmefene on subjective response to alcohol among non-treatment-seeking alcoholics and social drinkers. Alcohol Clin Exp Res. 2004 Sep;28(9):1362-1370. Pubmedid: 15365307.
  • Thomas S, Drobes D, Voronin K, Anton R. Following alcohol consumption, nontreatment-seeking alcoholics report greater stimulation but similar sedation compared with social drinkers. J Stud Alcohol. 2004 May;65(3):330-335. Pubmedid: 15222589.
  • Anton R, Drobes D, Voronin K, Durazo-Avizu R, Moak D. Naltrexone effects on alcohol consumption in a clinical laboratory paradigm: temporal effects of drinking. Psychopharmacology (Berl). 2004 Apr;173(1-2):32-40. Pubmedid: 14722705.
  • Myrick H, Anton RF, Li X, Henderson S, Drobes D, Voronin K, George MS. Differential brain activity in alcoholics and social drinkers to alcohol cues: relationship to craving. Neuropsychopharmacology. 2004 Feb;29(2):393-402. Pubmedid: 14679386.
  • Upadhyaya H, Drobes D, Thomas S. Reactivity to smoking cues in adolescent cigarette smokers. Addict Behav. 2004;29(5):849-856. Pubmedid: 15219329.
  • Drobes D, Cousino Klein L. Research on nicotine and tobacco: A decade of progress. Nicotine Tob Res. 2004;6(4):695-741. Pubmedid: 15370167.
  • Carrigan M, Drobes D, Randall C. Attentional bias and drinking to cope with social anxiety. Psychol Addict Behav. 2004;18(4):374-380. Pubmedid: 15631610.
  • Cuthbert BN, Lang PJ, Strauss C, Drobes D, Patrick CJ, Bradley MM. The psychophysiology of anxiety disorder: fear memory imagery. Psychophysiology. 2003 May;40(3):407-422. Pubmedid: 12946114.
  • Drobes DJ, Anton RF, Thomas SE, Voronin K. A clinical laboratory paradigm for evaluating medication effects on alcohol consumption: naltrexone and nalmefene. Neuropsychopharmacology. 2003 Apr;28(4):755-764. Pubmedid: 12655322.
  • Saladin M, Drobes D, Coffey S, Dansky B, Brady K, Kilpatrick D. PTSD symptom severity as a predictor of cue-elicited drug craving in victims of violent crime. Addict Behav. 2003;28(9):1611-1629. Pubmedid: 14656549.
  • Parrott D, Drobes D, Saladin M, Coffey S, Dansky B. Perpetration of partner violence: effects of cocaine and alcohol dependence and posttraumatic stress disorder. Addict Behav. 2003;28(9):1587-1602. Pubmedid: 14656547.
  • Saladin M, Drobes D, Coffey S, Libet J. The human startle reflex and alcohol cue reactivity: effects of early versus late abstinence. Psych Addic Behav. 2002 Jun;16(2):98-105. Pubmedid: 12079261.
  • Drobes D. Cue reactivity in alcohol and tobacco dependence. Alcohol Clin Exp Res. 2002;26(12):1928-1929. Pubmedid: 12500123.
  • Coffey S, Saladin M, Drobes D, Brady K, Dansky B, Kilpatrick D. Trauma and substance cue reactivity in individuals with comorbid posttraumatic stress disorder and cocaine or alcohol dependence. Drug Alcohol Depend. 2002;65(2):115-127. Pubmedid: 11772473.
  • Mann K, Agartz I, Harper C, Shoaf S, Rawlings R, Momenan R, Hommer D, Pfefferbaum A, Sullivan E, Anton R, Drobes D, George M, Bares R, Machulla HJ, Mundle G, Reimold M, Heinz A. Neuroimaging in alcoholism: ethanol and brain damage. Alcohol Clin Exp Res. 2001;25(5):104S-109S. Pubmedid: 11391058.
  • Drobes D, Miller E, Hillman C, Bradley M, Cuthbert B, Lang P. Food deprivation and emotional reactions to food cues: implications for eating disorders. Biol Psychol. 2001;57(1-3):153-177. Pubmedid: 11454438.
  • George M, Anton R, Bloomer C, Teneback C, Drobes D, Lorberbaum J, Nahas Z, Vincent D. Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues. Arch Gen Psychiatry. 2001;58(4):345-352. Pubmedid: 11296095.
  • Drobes DJ, Anton RF. Drinking in alcoholics following an alcohol challenge research protocol. J Stud Alcohol. 2000 Mar;61(2):220-224. Pubmedid: 10757131.
  • Geffken G, Zelikovsky N, Clark-Rudman J, Silverstein J, Drobes D. Poor metabolic control during menstruation and sexual abuse issues in an adolescent with diabetes. Br J Med Psychol. 2000;73(Pt 4):561-565. Pubmedid: 11140796.
  • Tiffany ST, Drobes DJ, Cepeda-Benito A. Contribution of associative and nonassociative processes to the development of morphine tolerance. Psychopharmacology (Berl). 1992;109(1-2):185-190. Pubmedid: 1365654.
  • Tiffany ST, Maude-Griffin PM, Drobes DJ. Effect of interdose interval on the development of associative tolerance to morphine in the rat: a dose-response analysis. Behav Neurosci. 1991 Feb;105(1):49-61. Pubmedid: 2025394.
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