Arnold B. Etame, MD, PhD

Where You Are:
Arnold B. Etame, MD, PhD

Assistant Member

Education And Training
  • PhD, University of Toronto, 2012 - Laboratory Medicine and Patholobiology
  • Resident, University of Michigan Medical Center, 2012 - Neurosurgery
  • Research Fellowship, Labbatt Brain Tumor Centre, Hospital for Sick Children, Toronto, 2011 - Neurosurgery Oncology
  • MD, University of Iowa College of Medicine, 2005


His research focuses on enhanced delivery of targeted therapeutics across the blood-brain barrier for malignant and metastatic brain tumors using nanotechnology and focused ultrasound disruption of the blood-brain barrier.  He is a principal investigator for clinical trial protocols in patients with malignant brain tumors. He will be leading a Phase III vaccine trial for patients with glioblastoma multiforme (GBM).

  • Diaz RJ, McVeigh PZ, O'Reilly MA, Burrell K, Bebenek M, Smith C, Etame A, Zadeh G, Hynynen K, Wilson BC, Rutka JT. Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: Potential for targeting experimental brain tumors. Nanomedicine. 2014 Jul;10(5):1075-1087. Pubmedid: 24374363. Pmcid: PMC4074278.
  • Ahmed KA, Sarangkasiri S, Chinnaiyan P, Sahebjam S, Yu HH, Etame AB, Rao NG. Outcomes Following Hypofractionated Stereotactic Radiotherapy in the Management of Brain Metastases. Am J Clin Oncol. 2014 Apr. Pubmedid: 24755663.
  • Kaloostian PE, Zadnik PL, Etame AB, Vrionis FD, Gokaslan ZL, Sciubba DM. Surgical management of primary and metastatic spinal tumors. Cancer Control. 2014 Apr;21(2):133-139. Pubmedid: 24667399.
  • Kaloostian PE, Yurter A, Etame AB, Vrionis FD, Sciubba DM, Gokaslan ZL. Palliative strategies for the management of primary and metastatic spinal tumors. Cancer Control. 2014 Apr;21(2):140-143. Pubmedid: 24667400.
  • Etame AB, Bentley JN, Pandey AS. Acute expansion of an asymptomatic posterior communicating artery aneurysm resulting in oculomotor nerve palsy. BMJ Case Rep. 2013 Jun;2013. Pubmedid: 23761613.
  • Niknafs YS, Wang AC, Than KD, Etame AB, Thompson BG, Sullivan SE. Hemorrhagic Vestibular Schwannoma: Review of the Literature. World Neurosurg. 2013 Feb. Pubmedid: 23454397.
  • Etame AB, Diaz RJ, O'Reilly MA, Smith CA, Mainprize TG, Hynynen K, Rutka JT. Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound. Nanomedicine. 2012 Oct;8(7):1133-1142. Pubmedid: 22349099.
  • Sagher O, Thawani JP, Etame AB, Gomez-Hassan DM. Seizure outcomes and mesial resection volumes following selective amygdalohippocampectomy and temporal lobectomy. Neurosurg Focus. 2012 Mar;32(3):E8. Pubmedid: 22380862.
  • Etame AB, Smith CA, Chan WC, Rutka JT. Design and potential application of PEGylated gold nanoparticles with size-dependent permeation through brain microvasculature. Nanomedicine. 2012 Mar;7(6):992-1000. Pubmedid: 21616168.
  • Etame AB, Diaz RJ, Smith CA, Mainprize TG, Hynynen K, Rutka JT. Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology. Neurosurg Focus. 2012 Jan;32(1):E3. Pubmedid: 22208896.
  • Etame AB, Fox WC, Sagher O. Osmotic diuresis paradoxically worsens brain shift after subdural grid placement. Acta Neurochir (Wien). 2011 Mar;153(3):633-637. Pubmedid: 21057826.
  • Onvani S, Etame AB, Smith CA, Rutka JT. Genetics of medulloblastoma: clues for novel therapies. Expert Rev Neurother. 2010 May;10(5):811-823. Pubmedid: 20420498.
  • Etame AB, Wang AC, Than KD, La Marca F, Park P. Outcomes after surgery for cervical spine deformity: review of the literature. Neurosurg Focus. 2010 Mar;28(3):E14. Pubmedid: 20192659.
  • Wang AC, Than KD, Etame AB, La Marca F, Park P. Impact of anesthesia on transcranial electric motor evoked potential monitoring during spine surgery: a review of the literature. Neurosurg Focus. 2009 Oct;27(4):E7. Pubmedid: 19795956.
  • Sack JA, Etame AB, Shah GV, La Marca F, Park P. Management and outcomes of patients undergoing surgery for traumatic cervical fracture-subluxation associated with an asymptomatic vertebral artery injury. J Spinal Disord Tech. 2009 Apr;22(2):86-90. Pubmedid: 19342928.
  • Than KD, Wang AC, Etame AB, La Marca F, Park P. Postoperative management of incidental durotomy in minimally invasive lumbar spinal surgery. Minim Invasive Neurosurg. 2008 Oct;51(5):263-266. Pubmedid: 18855289.
  • Etame AB, Than KD, Wang AC, La Marca F, Park P. Surgical management of symptomatic cervical or cervicothoracic kyphosis due to ankylosing spondylitis. Spine (Phila Pa 1976). 2008 Jul;33(16):E559-E564. Pubmedid: 18628698.
  • Sibenaller ZA, Etame AB, Ali MM, Barua M, Braun TA, Casavant TL, Ryken TC. Genetic characterization of commonly used glioma cell lines in the rat animal model system. Neurosurg Focus. 2005 Oct;19(4):E1. Pubmedid: 16241103.
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