Amit Mahipal, MD

Where You Are:
Amit Mahipal, MD

Assistant Member

Office  (813) 745-4106

Education And Training
  • Fellow, Thomas Jefferson University, 2011 - Hematology/Oncology
  • Chief Fellow, Thomas Jefferson University, 2011 - Hematology/Oncology
  • Resident, University of Connecticut, 2008 - Categorical Intern Medicine
  • MPH, University of Minnesota, 2005
  • MBBS, Maulana Azad Medical College, 2003

I am interested in drug development and early phase clinical trials (Phase I/II) in solid tumors and hematologic malignancies.  I would like to develop biologic markers that can identify patients who will obtain therpeutic benefit from the drugs to truly provide personalized care in oncology.

  • Papadopoulos KP, Isaacs R, Bilic S, Kentsch K, Huet HA, Hofmann M, Rasco D, Kundamal N, Tang Z, Cooksey J, Mahipal A. Unexpected hepatotoxicity in a phase I study of TAS266, a novel tetravalent agonistic Nanobody(®) targeting the DR5 receptor. Cancer Chemother Pharmacol. 2015 May;75(5):887-895. Pubmedid: 25721064.
  • Kazim S, Malafa MP, Coppola D, Husain K, Zibadi S, Kashyap T, Crochiere M, Landesman Y, Rashal T, Sullivan DM, Mahipal A. Selective nuclear export inhibitor KPT-330 enhances the antitumor activity of gemcitabine in human pancreatic cancer. Mol Cancer Ther. 2015 May. Pubmedid: 25934708.
  • Saneeymehri SS, Markey KR, Mahipal A. Paradoxical effect of capecitabine in 5-fluorouracil-induced cardiotoxicity: A case vignette and literature review. J Oncol Pharm Pract. 2015 Apr. Pubmedid: 25852107.
  • Kim R, Byer J, Fulp WJ, Mahipal A, Dinwoodie W, Shibata D. Carboplatin and paclitaxel treatment is effective in advanced anal cancer. Oncology-Basel. 2014 Sep;87(2):125-132. Pubmedid: 25012155.
  • Mahipal A, Nguyen D. Risks and benefits of phase 1 clinical trial participation. Cancer Control. 2014 Jul;21(3):193-199. Pubmedid: 24955702.
  • Denson AC, Mahipal A. Participation of the elderly population in clinical trials: barriers and solutions. Cancer Control. 2014 Jul;21(3):209-214. Pubmedid: 24955704.
  • Mahipal A. Clinical trials and drug development. Cancer Control. 2014 Jul;21(3):188-189. Pubmedid: 24955701.
  • Mahipal A, Kothari N, Gupta S. Epidermal growth factor receptor inhibitors: coming of age. Cancer Control. 2014 Jan;21(1):74-79. Pubmedid: 24357745.
  • Kim R, Mahipal A, Choi M, Saif MW. Biomarkers for Pancreatic Cancer: Is it Ready for Primetime?. JOP. 2013 Jul;14(4):309-311. Pubmedid: 23846914.
  • Gupta S, Mahipal A. Role of systemic chemotherapy in urothelial urinary bladder cancer. Cancer Control. 2013 Jul;20(3):200-210. Pubmedid: 23811704.
  • Mahipal A, Tijani L, Chan K, Laudadio M, Mastrangelo MJ, Sato T. A pilot study of sunitinib malate in patients with metastatic uveal melanoma. Melanoma Res. 2012 Dec;22(6):440-446. Pubmedid: 23114504.
  • Mahipal A, McDonald MJ, Witkiewicz A, Carr BI. Cell membrane and cytoplasmic epidermal growth factor receptor expression in pancreatic ductal adenocarcinoma. Med Oncol. 2012 Mar;29(1):134-139. Pubmedid: 21264542.
  • Sbenghe MM, Besa E, Mahipal A, Dulau Florea A, Bray P, Caro J. HHV-8-associated multicentric Castleman's disease in HIV-negative patient: a novel therapy for an orphan disease. Oncologist. 2012;17(1):145-146. Pubmedid: 22286773. Pmcid: PMC3267815.
  • Mahipal A, Gupta S. Small-cell carcinoma of the gallbladder: report of a case and literature review. Gastrointest Cancer Res. 2011 Jul;4(4):135-136. Pubmedid: 22368737. Pmcid: PMC3283103.
  • Mahipal A, Terai M, Berd D, Chervoneva I, Patel K, Mastrangelo MJ, Sato T. Tumor-derived interleukin-10 as a prognostic factor in stage III patients undergoing adjuvant treatment with an autologous melanoma cell vaccine. Cancer Immunol Immunother. 2011 Jul;60(7):1039-1045. Pubmedid: 21519827.
  • Mahipal A, Weiss M. The addition of rituximab to fludarabine and cyclophosphamide improves progression-free survival in patients with previously treated chronic lymphocytic leukemia. Curr Oncol Rep. 2010 Nov;12(6):352-354. Pubmedid: 20809225.
  • Gupta S, Mahipal A. A case of acquired hemophilia associated with bullous pemphigoid. Am J Hematol. 2007 Jun;82(6):502. Pubmedid: 17301969.
  • Mahipal A, Bilgrami S. Acquired hemophilia in chronic lymphocytic leukemia. Leuk Lymphoma. 2007 May;48(5):1026-1028. Pubmedid: 17487748.
  • Gupta S, Mahipal A. Fatal pulmonary toxicity after a single dose of cyclophosphamide. Pharmacotherapy. 2007 Apr;27(4):616-618. Pubmedid: 17381391.
  • Mahipal A, Anderson KE, Limburg PJ, Folsom AR. Nonsteroidal anti-inflammatory drugs and subsite-specific colorectal cancer incidence in the Iowa women's health study. Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1785-1790. Pubmedid: 17035383.
  • Swenson KK, Mahipal A, Nissen MJ, Tuttle TM, Heaton K, Lally RM, Spomer A, Lee MW. Axillary disease recurrence after sentinel lymph node dissection for breast carcinoma. Cancer. 2005 Nov;104(9):1834-1839. Pubmedid: 16161037.
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