Thomas J. Dilling, MD

Where You Are:

Thomas J. Dilling, MD

Radiation Therapy


          •  Radiation Oncology

          •  University of Pennsylvania - Radiation Oncology

          •  University of Pennsylvania - Radiation Oncology

          •  University of Pennsylvania - MD

  • Ahmed KA, Fulp WJ, Berglund AE, Hoffe SE, Dilling TJ, Eschrich SA, Shridhar R, Torres-Roca JF. Differences Between Colon Cancer Primaries and Metastases Using a Molecular Assay for Tumor Radiation Sensitivity Suggest Implications for Potential Oligometastatic SBRT Patient Selection. Int J Radiat Oncol Biol Phys. 2015 Mar. Pubmedid: 25838188.

  • D'Ambrosio DJ, Bayouth J, Chetty IJ, Buyyounouski MK, Price RA, Correa CR, Dilling TJ, Franklin GE, Xia P, Harris EE, Konski A. Continuous localization technologies for radiotherapy delivery: Report of the American Society for Radiation Oncology Emerging Technology Committee. Pract Radiat Oncol. 2015 Mar;2(2):145-150. Pubmedid: 24175000. Pmcid: PMC3808750.

  • Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Dilling TJ, Govindan R, Grannis FW, Horn L, Jahan TM, Komaki R, Kris MG, Krug LM, Lackner RP, Lanuti M, Lilenbaum R, Lin J, Loo BW, Martins R, Otterson GA, Patel JD, Pisters KM, Reckamp K, Riely GJ, Rohren E, Schild S, Shapiro TA, Swanson SJ, Tauer K, Yang SC, Gregory K, Hughes M. Non-small cell lung cancer, version 1.2015. J Natl Compr Canc Ne. 2014 Dec;12(12):1738-1761. Pubmedid: 25505215.

  • Ahmed KA, Correa CR, Dilling TJ, Rao NG, Shridhar R, Trotti AM, Wilder RB, Caudell JJ. Altered fractionation schedules in radiation treatment: a review. Semin Oncol. 2014 Dec;41(6):730-750. Pubmedid: 25499633.

  • Dilling TJ, Extermann M, Kim J, Thompson LM, Yue B, Stevens CW, Antonia S, Gray J, Williams C, Haura E, Pinder-Schenck M, Tanvetyanon T, Kim S, Chiappori A. Phase 2 study of concurrent cetuximab plus definitive thoracic radiation therapy followed by consolidation docetaxel plus cetuximab in poor prognosis or elderly patients with locally advanced non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2014 Nov;90(4):828-833. Pubmedid: 25216856.

  • Latifi K, Oliver J, Baker R, Dilling TJ, Stevens CW, Kim J, Yue B, Demarco M, Zhang GG, Moros EG, Feygelman V. Study of 201 non-small cell lung cancer patients given stereotactic ablative radiation therapy shows local control dependence on dose calculation algorithm. Int J Radiat Oncol Biol Phys. 2014 Apr;88(5):1108-1113. Pubmedid: 24529716.

  • Latifi K, Dilling TJ, Hoffe SE, Stevens CW, Moros EG, Zhang GG. Evaluating Effects of Radiation Therapy Treatment on 4DCT-Calculated Lung Ventilation. Pract Radiat Oncol. 2014 Mar;3(2 Suppl 1):S6-S7. Pubmedid: 24674563.

  • Figura N, Latifi K, Dilling TJ, Kuykendall CC, Eikman EA, Moros EG, Zhang GG, Leuthold S, Mehra C, Hoffe SE. Dosimetric Implications of Treating 4D PET/CT-Defined Maximum Inhale Versus Exhale Target Volumes in Esophageal Cancer. Pract Radiat Oncol. 2014 Mar;3(2 Suppl 1):S34-S35. Pubmedid: 24674556.

  • Budzevich MM, Kuykendall CC, Latifi K, Oliver J, Dilling TJ, Hoffe SE, Eikman EA, Montilla-Soler JI, Zhang GG, Moros EG. A Method to Determine the Optimal Number of Bins in 4D PET. Pract Radiat Oncol. 2014 Mar;3(2 Suppl 1):S25. Pubmedid: 24674527.

  • Zhang GG, Latifi K, Huang T, Feygelman V, Stevens CW, Dilling TJ, Moros EG, Elmpt Wv, Dekker A. Effects of Noise in 4D CT on Deformable Image Registration and Derived Ventilation Data. Pract Radiat Oncol. 2014 Mar;3(2 Suppl 1):S7-S8. Pubmedid: 24674566.

  • Kuykendall CC, Budzevich MM, Latifi K, Moros EG, Hoffe SE, Dilling TJ, Zhang GG, Montilla-Soler JL, Eikman EA. 4D PET/CT: Radiology Imaging to Radiation Therapy. Pract Radiat Oncol. 2014 Mar;3(2 Suppl 1):S28. Pubmedid: 24674534.

  • Latifi K, Huang TC, Feygelman V, Budzevich MM, Moros EG, Dilling TJ, Stevens CW, van Elmpt W, Dekker A, Zhang GG. Effects of quantum noise in 4D-CT on deformable image registration and derived ventilation data. Phys Med Biol. 2013 Nov;58(21):7661-7672. Pubmedid: 24113375.

  • Stambaugh C, Nelms BE, Dilling T, Stevens C, Latifi K, Zhang G, Moros E, Feygelman V. Experimentally studied dynamic dose interplay does not meaningfully affect target dose in VMAT SBRT lung treatments. Med Phys. 2013 Sep;40(9):091710. Pubmedid: 24007143.

  • Latifi K, Forster KM, Hoffe SE, Dilling TJ, Dekker A, Van Elmpt W, Zhang GG. Dependence of ventilation image derived from 4D CT on deformable image registration and ventilation algorithms. J Appl Clin Med Phys. 2013 Jul;14(4):4247. Pubmedid: 23835389.

  • Ramnath N, Dilling TJ, Harris LJ, Kim AW, Michaud GC, Balekian AA, Diekemper R, Detterbeck FC, Arenberg DA. Treatment of stage III non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013 May;143(5 Suppl):e314S-e340S. Pubmedid: 23649445.

  • Saeed N, Latifi K, Hoffe SE, Cruz A, Opp DW, Moros EG, Zhang GG, Budzevich MM, Shridhar R, Dilling TJ. Optimizing Options for Re-irradiation With Deformable Image Registration of Prior Plans. Pract Radiat Oncol. 2013 Apr;3(2 Suppl 1):S16-S17. Pubmedid: 24674497.

  • Baker R, Han G, Sarangkasiri S, DeMarco M, Turke C, Stevens CW, Dilling TJ. Clinical and dosimetric predictors of radiation pneumonitis in a large series of patients treated with stereotactic body radiation therapy to the lung. Int J Radiat Oncol Biol Phys. 2013 Jan;85(1):190-195. Pubmedid: 22929858.

  • Latifi K, Feygelman V, Moros EG, Dilling TJ, Stevens CW, Zhang GG. Normalization of ventilation data from 4D-CT to facilitate comparison between datasets acquired at different times. PLoS One. 2013;8(12):e84083. Pubmedid: 24358330. Pmcid: PMC3866128.

  • Ahmed I, Demarco M, Stevens CW, Fulp WJ, Dilling TJ. Analysis of incidental radiation dose to uninvolved mediastinal/supraclavicular lymph nodes in patients with limited-stage small cell lung cancer treated without elective nodal irradiation. Med Dosim. 2012 Apr;36(4):440-447. Pubmedid: 21397488.

  • Zhang GG, Ku L, Dilling TJ, Stevens CW, Zhang RR, Li W, Feygelman V. Volumetric modulated arc planning for lung stereotactic body radiotherapy using conventional and unflattened photon beams: a dosimetric comparison with 3D technique. Radiat Oncol. 2012 Mar;6:152. Pubmedid: 22070866. Pmcid: PMC3354344.

  • Dilling TJ, Bae K, Paulus R, Watkins-Bruner D, Garden AS, Forastiere A, Kian Ang K, Movsas B. Impact of gender, partner status, and race on locoregional failure and overall survival in head and neck cancer patients in three radiation therapy oncology group trials. Int J Radiat Oncol Biol Phys. 2011 Nov;81(3):e101-e109. Pubmedid: 21549515. Pmcid: PMC3170693.

  • Zhang G, Huang TC, Dilling T, Stevens C, Forster K. Comments on 'Ventilation from four-dimensional computed tomography: density versus Jacobian methods'. Phys Med Biol. 2011 Jun;56(11):3445-3446. Pubmedid: 21572233.

  • Zhang G, Feygelman V, Huang TC, Stevens C, Li W, Dilling T. Motion-weighted target volume and dose-volume histogram: A practical approximation of four-dimensional planning and evaluation. Radiother Oncol. 2011 Apr;99(1):67-72. Pubmedid: 21397967.

  • Bepler G, Dilling TJ, Wagner H, Hazelton T, Williams C, Chen DT, Greenberg H, Walsh F, Simon G, Tanvetyanon T, Chiappori A, Haura E, Stevens C. Phase II trial of induction gemcitabine and carboplatin followed by conformal thoracic radiation to 74 Gy with weekly paclitaxel and carboplatin in unresectable stage III non-small cell lung cancer. J Thorac Oncol. 2011 Mar;6(3):553-558. Pubmedid: 21289520.

  • Buyyounouski MK, Balter P, Lewis B, D'Ambrosio DJ, Dilling TJ, Miller RC, Schefter T, Tom? W, Harris EE, Price RA, Konski AA, Wallner PE. Stereotactic body radiotherapy for early-stage non-small-cell lung cancer: report of the ASTRO Emerging Technology Committee. Int J Radiat Oncol Biol Phys. 2010 Sep;78(1):3-10. Pubmedid: 20643514.

  • Huang TC, Liang JA, Dilling T, Wu TH, Zhang G. Four-dimensional dosimetry validation and study in lung radiotherapy using deformable image registration and Monte Carlo techniques. Radiat Oncol. 2010 Aug;5:45. Pubmedid: 20509955. Pmcid: PMC2890615.

  • Barthel JS, Kucera ST, Lin JL, Hoffe SE, Strosberg JR, Ahmed I, Dilling TJ, Stevens CW. Does Barrett's esophagus respond to chemoradiation therapy for adenocarcinoma of the esophagus?. Gastrointest Endosc. 2010 Feb;71(2):235-240. Pubmedid: 20003971.

  • Faygelman V, Hunt D, Walker L, Mueller R, Demarco ML, Dilling T, Stevens C, Zhang G. Validation of Pinnacle treatment planning system for use with Novalis delivery unit. J Appl Clin Med Phys. 2010;11(3):3240. Pubmedid: 20717094.

  • Evans SM, Jenkins KW, Jenkins WT, Dilling T, Judy KD, Schrlau A, Judkins A, Hahn SM, Koch CJ. Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors. Radiat Res. 2008 Dec;170(6):677-690. Pubmedid: 19138031. Pmcid: PMC2629387.

  • Zhang G, Dilling T, Stevens C, Forster K. Functional lung imaging in thoracic cancer radiotherapy. Cancer Control. 2008 Apr;15(2):112-119. Pubmedid: 18376378.

  • Dilling TJ, Hoffe SE. Stereotactic body radiation therapy: transcending the conventional to improve outcomes. Cancer Control. 2008 Apr;15(2):104-111. Pubmedid: 18376377.

  • Emrich JG, Hand CM, Dilling TJ, Class R, Bender H, Brady LW. Biodistribution of 125I-MAb 425 in a human glioma xenograft model: effect of chloroquine. Hybridoma. 1997 Feb;16(1):93-100. Pubmedid: 9085135.

My primary clinical focus is the radiotherapeutic treatment of thoracic malignancies. I am interested in the application of new technologies to the treatment of lung cancer, with the ongoing goal to improve treatment efficacy while minimizing untoward side effects. In particular, I am interested in the use of stereotactic radiotherapy for the treatment of early-stage lung cancers.

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