Ricardo J. Gonzalez, MD

Where You Are:

Ricardo J. Gonzalez, MD



          •  Surgery

          •  University of Texas MD Anderson Cancer Center - Surgical Oncology

          •  University of Colorado - Surgery

          •  University of South Florida - MD

  • Yamamoto M, Fisher KJ, Wong JY, Koscso JM, Konstantinovic MA, Govsyeyev N, Messina JL, Sarnaik AA, Cruse CW, Gonzalez RJ, Sondak VK, Zager JS. Sentinel lymph node biopsy is indicated for patients with thick clinically lymph node-negative melanoma. Cancer. 2015 May;121(10):1628-1636. Pubmedid: 25677366.

  • Bakalis S, Peeva G, Gonzalez R, Poon LC, Nicolaides KH. Prediction of small-for-gestational-age neonates: screening by biophysical and biochemical markers at 30-34 weeks. Ultrasound Obstet Gynecol. 2015 Mar. Pubmedid: 25826154.

  • von Mehren M, Randall RL, Benjamin RS, Boles S, Bui MM, Casper ES, Conrad EU, Delaney TF, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Kane JM, Mayerson J, McGarry SV, Meyer C, O'Donnell RJ, Pappo AS, Paz IB, Pfeifer JD, Riedel RF, Schuetze S, Schupak KD, Schwartz HS, Van Tine BA, Wayne JD, Bergman MA, Sundar H. Soft tissue sarcoma, version 2.2014. J Natl Compr Canc Ne. 2014 Apr;12(4):473-483. Pubmedid: 24717567.

  • Toloza E, Sobky C, Pimiento J, Garrett J, Pappas-Politis E, Deneve J, Kim D, Plank D, Smith P, Gonzalez R. Multilevel Costovertebral Reconstruction With the Synthes MatrixRIB Fixation System and Vicryl Mesh After Radical Chest Wall Resection for Sarcoma: A Case Report. Chest. 2014 Mar;145(3 Suppl):34A. Pubmedid: 24638509.

  • Rusthoven CG, Liu AK, Bui MM, Schefter TE, Elias AD, Lu X, Gonzalez RJ. Sarcomas of the Aorta: A Systematic Review and Pooled Analysis of Published Reports. Ann Vasc Surg. 2014 Feb;28(2):515-525. Pubmedid: 24485779.

  • Deneve JL, Messina JL, Bui MM, Marzban SS, Letson GD, Cheong D, Gonzalez RJ, Sondak VK, Zager JS. Cutaneous leiomyosarcoma: treatment and outcomes with a standardized margin of resection. Cancer Control. 2013 Oct;20(4):307-312. Pubmedid: 24077407.

  • de la Fuente SG, Deneve JL, Parsons CM, Zager JS, Conley AP, Gonzalez RJ. A comparison between patients with gastrointestinal stromal tumours diagnosed with isolated liver metastases and liver metastases plus sarcomatosis. HPB (Oxford). 2013 Sep;15(9):655-660. Pubmedid: 23458233. Pmcid: PMC3948531.

  • Perez MC, Padhya TA, Messina JL, Jackson RS, Gonzalez RJ, Bui MM, Letson GD, Cruse CW, Lavey RS, Cheong D, Forster MR, Fulp WJ, Sondak VK, Zager JS. Cutaneous angiosarcoma: a single-institution experience. Ann Surg Oncol. 2013 Jul;20(11):3391-3397. Pubmedid: 23835652.

  • Vohra NA, Turaga KK, Gonzalez RJ, Conley A, Reed D, Bui MM, Cheong D, Letson DG, Zager JS. The use of isolated limb infusion in limb threatening extremity sarcomas. Int J Hyperthermia. 2013 Jun;29(1):1-7. Pubmedid: 23205633.

  • Deneve JL, Turaga KK, Marzban SS, Puleo CA, Sarnaik AA, Gonzalez RJ, Sondak VK, Zager JS. Single-institution outcome experience using AlloDerm? as temporary coverage or definitive reconstruction for cutaneous and soft tissue malignancy defects. Am Surg. 2013 May;79(5):476-482. Pubmedid: 23635582.

  • Deneve JL, Choi J, Gonzalez RJ, Conley AP, Stewart S, Han D, Werner P, Chaudhry TA, Zager JS. Chemosaturation with percutaneous hepatic perfusion for unresectable isolated hepatic metastases from sarcoma. Cardiovasc Intervent Radiol. 2012 Dec;35(6):1480-1487. Pubmedid: 22699779.

  • Han D, Yu D, Zhao X, Marzban SS, Messina JL, Gonzalez RJ, Wayne Cruse C, Sarnaik AA, Puleo C, Sondak VK, Zager JS. Sentinel Node Biopsy is Indicated for Thin Melanomas??0.76?mm. Ann Surg Oncol. 2012 Oct;19(11):3335-3342. Pubmedid: 22766986.

  • Deneve JL, Messina JL, Marzban SS, Gonzalez RJ, Walls BM, Fisher KJ, Ann Chen Y , Wayne Cruse C, Sondak VK, Zager JS. Merkel cell carcinoma of unknown primary origin. Ann Surg Oncol. 2012 Jul;19(7):2360-2366. Pubmedid: 22271206.

  • Parsons CM, Pimiento JM, Cheong D, Marzban SS, Gonzalez RJ, Johnson D, Letson GD, Zager JS. The role of radical amputations for extremity tumors: a single institution experience and review of the literature. J Surg Oncol. 2012 Feb;105(2):149-155. Pubmedid: 21837679.

  • Finkelstein SE, Iclozan C, Bui MM, Cotter MJ, Ramakrishnan R, Ahmed J, Noyes DR, Cheong D, Gonzalez RJ, Heysek RV, Berman C, Lenox BC, Janssen W, Zager JS, Sondak VK, Letson GD, Antonia SJ, Gabrilovich DI. Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients. Int J Radiat Oncol Biol Phys. 2012 Feb;82(2):924-932. Pubmedid: 21398051. Pmcid: PMC4241354.

  • Han D, Deneve J, Gonzalez RJ. Recurrence risk after resection of gastrointestinal stromal tumors: size is not all that matters... The consequences of tumor rupture. Am Surg. 2012 Jan;78(1):74-79. Pubmedid: 22273319.

  • Mullinax JE, Zager JS, Gonzalez RJ. Current diagnosis and management of retroperitoneal sarcoma. Cancer Control. 2011 Jul;18(3):177-187. Pubmedid: 21666580.

  • Riddle ND, Gonzalez RJ, Bridge JA, Antonia S, Bui MM. A CD117 and CD34 immunoreactive sarcoma masquerading as a gastrointestinal stromal tumor: diagnostic pitfalls of ancillary studies in sarcoma. Cancer Control. 2011 Jul;18(3):152-159. Pubmedid: 21666577.

  • Cheong D, Gonzalez RJ, Zager JS. Strategies for solutions in sarcoma management. Cancer Control. 2011 Jul;18(3):148-149. Pubmedid: 21666576.

  • Turaga KK, Beasley GM, Kane JM, Delman KA, Grobmyer SR, Gonzalez RJ, Letson GD, Cheong D, Tyler DS, Zager JS. Limb preservation with isolated limb infusion for locally advanced nonmelanoma cutaneous and soft-tissue malignant neoplasms. Arch Surg. 2011 Jul;146(7):870-875. Pubmedid: 21768436.

  • Sondak VK, Gonzalez RJ, Kudchadkar R. Adjuvant therapy for melanoma: a surgical perspective. Surg Oncol Clin N Am. 2011 Jan;20(1):105-114. Pubmedid: 21111961.

  • Bui MM, Han G, Acs G, Reed D, Gonzalez RJ, Pasha TL, Zhang PJ. Connexin 43 is a potential prognostic biomarker for ewing sarcoma/primitive neuroectodermal tumor. Sarcoma. 2011;2011:971050. Pubmedid: 21647307. Pmcid: PMC3103998.

  • Rusthoven C, Shames ML, Bui MM, Gonzalez RJ. High-grade undifferentiated pleomorphic sarcoma of the aortic arch: a case of endovascular therapy for embolic prophylaxis and review of the literature. Vasc Endovascular Surg. 2010 Jul;44(5):385-391. Pubmedid: 20538733.

  • Gonzalez RJ, Padhya TA, Cherpelis BS, Prince MD, Aya-Ay ML, Sondak VK, Cruse CW, Zager JS. The surgical management of primary and metastatic Merkel cell carcinoma. Curr Probl Cancer. 2010 Jan-Feb;34(1):77-96. Pubmedid: 20371076.

  • Gonzalez RJ, Kudchadkar R, Rao NG, Sondak VK. Adjuvant Immunotherapy and Radiation in the Management of High-risk Resected Melanoma. Ochsner J. 2010;10(2):108-116. Pubmedid: 21603365. Pmcid: PMC3096199.

  • O'Day SJ, Atkins MB, Boasberg P, Wang HJ, Thompson JA, Anderson CM, Gonzalez R, Lutzky J, Amatruda T, Hersh EM, Weber JS. Phase II multicenter trial of maintenance biotherapy after induction concurrent Biochemotherapy for patients with metastatic melanoma. J Clin Oncol. 2009 Dec;27(36):6207-6212. Pubmedid: 19917850.

  • Chang GJ, Gonzalez RJ, Skibber JM, Eng C, Das P, Rodriguez-Bigas MA. A twenty-year experience with adenocarcinoma of the anal canal. Dis Colon Rectum. 2009 Aug;52(8):1375-1380. Pubmedid: 19617747.

  • Hauschild A, Agarwala SS, Trefzer U, Hogg D, Robert C, Hersey P, Eggermont A, Grabbe S, Gonzalez R, Gille J, Peschel C, Schadendorf D, Garbe C, O'Day S, Daud A, White JM, Xia C, Patel K, Kirkwood JM, Keilholz U. Results of a Phase III, Randomized, Placebo-Controlled Study of Sorafenib in Combination With Carboplatin and Paclitaxel As Second-Line Treatment in Patients With Unresectable Stage III or Stage IV Melanoma. J Clin Oncol. 2009 Jun;27(17):2823-2830. Pubmedid: 19349552.

  • Howe R, Dillon S, Rogers L, McCarter M, Kelly C, Gonzalez R, Madinger N, Wilson CC. Evidence for dendritic cell-dependent CD4(+) T helper-1 type responses to commensal bacteria in normal human intestinal lamina propria. Clin Immunol. 2009 May;131(2):317-332. Pubmedid: 19174326. Pmcid: PMC2720400.

  • Fleming JB, Gonzalez RJ, Petzel MQ, Lin E, Morris JS, Gomez H, Lee JE, Crane CH, Pisters PW, Evans DB. Influence of obesity on cancer-related outcomes after pancreatectomy to treat pancreatic adenocarcinoma. Arch Surg. 2009 Mar;144(3):216-221. Pubmedid: 19289659.

  • Bashir Q, Lee CK, Stuart RW, Smith ML, Ryder J, Gonzalez R. Phenotypic evolution of Waldenstrom's macroglobulinemia to extramedullary plasmacytoma. J Clin Oncol. 2008 May;26(14):2408-2410. Pubmedid: 18467735.

  • Gonzalez RJ, Barnett CC. A technique for safely teaching major hepatectomy to surgical residents. Am J Surg. 2008 Apr;195(4):521-525. Pubmedid: 18304505.

  • Kudchadkar R, Gonzalez R, Lewis K, Treichel K, Hammerman S, Robinson W, Fitzpatrick J, Gonzalez R, Kavanagh B, Rusthoven K. A case of Merkel cell carcinoma. Oncology (Williston Park). 2008 Mar;22(3):322-328. Pubmedid: 18494357.

  • Gonzalez RJ, Tamm EP, Ng C, Phan AT, Vassilopoulou-Sellin R, Perrier ND, Evans DB, Lee JE. Response to mitotane predicts outcome in patients with recurrent adrenal cortical carcinoma. Surgery. 2007 Dec;142(6):867-875. Pubmedid: 18063070.

  • Boughey JC, Gonzalez RJ, Bonner E, Kuerer HM. Current treatment and clinical trial developments for ductal carcinoma in situ of the breast. Oncologist. 2007 Nov;12(11):1276-1287. Pubmedid: 18055847.

  • Richards JG, Wang YS, Brauner CJ, Gonzalez RJ, Patrick ML, Schulte PM, Choppari-Gomes AR, Almeida-Val VM, Val AL. Metabolic and ionoregulatory responses of the Amazonian cichlid, Astronotus ocellatus, to severe hypoxia. J Comp Physiol B. 2007 Apr;177(3):361-374. Pubmedid: 17219139.

  • Gonzalez RJ, Shapiro S, Sarlis N, Vassilopoulou-Sellin R, Perrier ND, Evans DB, Lee JE. Laparoscopic resection of adrenal cortical carcinoma: a cautionary note. Surgery. 2005 Dec;138(6):1078-1085. Pubmedid: 16360394.

  • Gonzalez RJ, Mansfield PF. Adjuvant and neoadjuvant therapy for gastric cancer. Surg Clin North Am. 2005 Oct;85(5):1033-51, viii. Pubmedid: 16139035.

  • Preest MR, Gonzalez RJ, Wilson RW. A pharmacological examination of Na+ and Cl- transport in two species of freshwater fish. Physiol Biochem Zool. 2005 Jun;78(2):259-272. Pubmedid: 15778945.

  • Roaten JB, Partrick DA, Pearlman N, Gonzalez RJ, Gonzalez R, McCarter MD. Sentinel lymph node biopsy for melanoma and other melanocytic tumors in adolescents. J Pediatr Surg. 2005 Jan;40(1):232-235. Pubmedid: 15868590.

  • Roaten JB, Pearlman N, Gonzalez R, Gonzalez R, McCarter MD. Identifying risk factors for complications following sentinel lymph node biopsy for melanoma. Arch Surg. 2005 Jan;140(1):85-89. Pubmedid: 15655211.

  • Silliman CC, Moore EE, Johnson JL, Gonzalez RJ, Biffl WL. Transfusion of the injured patient: proceed with caution. Shock. 2004 Apr;21(4):291-299. Pubmedid: 15179127.

  • Gonzalez RJ, McCarter MD, McDermott T, Pearlman NW. Transsacral exenteration of fixed primary and recurrent anorectal cancer. Am J Surg. 2003 Dec;186(6):670-674. Pubmedid: 14672777.

  • Gonzalez RJ, Moore EE, Ciesla DJ, Nieto JR, Johnson JL, Silliman CC. Post-hemorrhagic shock mesenteric lymph activates human pulmonary microvascular endothelium for in vitro neutrophil-mediated injury: the role of intercellular adhesion molecule-1. J Trauma. 2003 Feb;54(2):219-223. Pubmedid: 12579043.

  • Johnson JL, Moore EE, Gonzalez RJ, Fedel N, Partrick DA, Silliman CC. Alteration of the postinjury hyperinflammatory response by means of resuscitation with a red cell substitute. J Trauma. 2003 Jan;54(1):133-139. Pubmedid: 12544908.

  • Silliman CC, Moore EE, Zallen G, Gonzalez R, Johnson JL, Elzi DJ, Meng X, Hanasaki K, Ishizaki J, Arita H, Ao L, England KM, Banerjee A. Presence of the M-type sPLA(2) receptor on neutrophils and its role in elastase release and adhesion. Am J Physiol Cell Physiol. 2002 Oct;283(4):C1102-C1113. Pubmedid: 12225974.

  • Gonzalez RJ, Moore EE, Ciesla DJ, Neto JR, Biffl WL, Silliman CC. Hyperosmolarity abrogates neutrophil cytotoxicity provoked by post-shock mesenteric lymph. Shock. 2002 Jul;18(1):29-32. Pubmedid: 12095130.

  • Biffl WL, Myers A, Franciose RJ, Gonzalez RJ, Darnell D. Is breast cancer in young Latinas a different disease?. Am J Surg. 2001 Dec;182(6):596-600. Pubmedid: 11839323.

  • Gonzalez RJ, Moore EE, Ciesla DJ, Biffl WL, Johnson JL, Silliman CC. Mesenteric lymph is responsible for post-hemorrhagic shock systemic neutrophil priming. J Trauma. 2001 Dec;51(6):1069-1072. Pubmedid: 11740254.

  • Gonzalez RJ, Moore EE, Ciesla DJ, Biffl WL, Offner PJ, Silliman CC. Phospholipase A(2)--derived neutral lipids from posthemorrhagic shock mesenteric lymph prime the neutrophil oxidative burst. Surgery. 2001 Aug;130(2):198-203. Pubmedid: 11490349.

  • Biffl WL, Smith WR, Moore EE, Gonzalez RJ, Morgan SJ, Hennessey T, Offner PJ, Ray CE, Franciose RJ, Burch JM. Evolution of a multidisciplinary clinical pathway for the management of unstable patients with pelvic fractures. Ann Surg. 2001 Jun;233(6):843-850. Pubmedid: 11407336. Pmcid: PMC1421328.

  • Ciesla DJ, Moore EE, Biffl WL, Gonzalez RJ, Silliman CC. Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge. Surgery. 2001 May;129(5):567-575. Pubmedid: 11331449.

  • Biffl WL, Moore EE, Offner PJ, Ciesla DJ, Gonzalez RJ, Silliman CC. Plasma from aged stored red blood cells delays neutrophil apoptosis and primes for cytotoxicity: abrogation by poststorage washing but not prestorage leukoreduction. J Trauma. 2001 Mar;50(3):426-431. Pubmedid: 11265021.

  • Biffl WL, West KE, Moore EE, Gonzalez RJ, Carnaggio R, Offner PJ, Silliman CC. Neutrophil apoptosis is delayed by trauma patients' plasma via a mechanism involving proinflammatory phospholipids and protein kinase C. Surg Infect (Larchmt). 2001;2(4):289-293. Pubmedid: 12593704.

  • Gonzalez RJ, Moore EE, Biffl WL, Ciesla DJ, Silliman CC. The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential. Shock. 2000 Sep;14(3):404-408. Pubmedid: 11028564.

  • Ciesla DJ, Moore EE, Gonzalez RJ, Biffl WL, Silliman CC. Hypertonic saline inhibits neutrophil (PMN) priming via attenuation of p38 MAPK signaling. Shock. 2000 Sep;14(3):265-269. Pubmedid: 11028541.

  • Bloomston M, Zervos E, Gonzalez R, Albrink M, Rosemurgy, A. Quality of life and antireflux medication use following laparoscopic Nissen fundoplication. Am Surg. 1998 Jun;64(6):509-513. Pubmedid: 9619170.

  • Cox CE, Hyacinthe M, Gonzalez RJ, Ku NN, Greenberg H, Reintgen D, Lyman G, Nicosia SV. Cytologic evaluation of lumpectomy margins in patients with ductal carcinoma in-situ: clinical outcome. Ann Surg Oncol. 1997 Dec;4(8):644-649. Pubmedid: 9416412.

  • Gonzalez RJ, Buzdar AU, Fraser Symmans W, Yen TW, Broglio KR, Lucci A, Esteva FJ, Yin G, Kuerer HM. Novel clinical trial designs for treatment of ductal carcinoma in situ of the breast with trastuzumab (herceptin). Breast J. 13(1):72-75. Pubmedid: 17214797.

  • Rabaglia JL, Gonzalez R, Moore EE, Harken AH. Pooled human albumin primes neutrophils. J Card Surg. 17(3):209-213. Pubmedid: 12489905.

Dr. Ricardo Gonzalez is a surgical oncologist and Chair of the Sarcoma Department at Moffitt Cancer Center. He also serves as a member of the Cutaneous Program at Moffitt Cancer Center.  He is an associate professor at the University Of South Florida College Of Medicine’s Department of Oncologic Sciences and Department of Surgery.


Dr. Gonzalez’ research and clinical interests include outcomes analyses and management of patients with soft tissue sarcomas, retroperitoneal sarcomas, desmoid tumors, gastrointestinal stromal tumors (GIST) and head and neck melanoma.


Dr. Gonzalez received his undergraduate degree and medical degree from the University of South Florida and completed a residency in surgery at the University of Colorado Health Sciences Center.  During his time in Colorado he also completed a 2 year research fellowship in inflammatory biology and resuscitation. He completed his residency training and followed with a fellowship in surgical oncology at the University of Texas MD Anderson Cancer Center. While in Houston Texas studying the intricacies of surgical oncology he also completed a research fellowship in tumor biology. As well he was a clinical specialist in anesthesia and critical care, as well as surgical oncology.

Prior to joining Moffitt in 2008, Dr. Gonzalez returned to the University of Colorado as an assistant professor in the Department of Surgery’s Division of GI, Tumor and Endocrine Surgery.

Dr. Gonzalez received several awards during his training at the University of Colorado, including the J. Cothbert Owens MD, Excellence in Teaching & Patient Care Award, the Earl G. Young Distinguished Researcher Award and outstanding clinical instructor. While at Moffitt Cancer Center he has been nominated for physician of the year, and received awards for excellence in safety.


He is a fellow of the American College of Surgeons, a member of the National Comprehensive Cancer Network Sarcoma Panel, the Connective Tissue Oncology Society and the Society of Surgical oncology.


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