Ravi Shridhar, MD, PhD

Where You Are:

Ravi Shridhar, MD, PhD

Radiation Therapy

For Consultation Requests or Referrals: (813) 745-3053


          •  Radiation Oncology


          •  Detroit Medical Center/Wayne State University - Radiation Oncology

          •  Wayne State University - MD

  • Shridhar R, Freilich J, Hoffe SE, Almhanna K, Fulp WJ, Yue B, Karl RC, Meredith K. Single-Institution Retrospective Comparison of Preoperative Versus Definitive Chemoradiotherapy for Adenocarcinoma of the Esophagus. Ann Surg Oncol. 2014 May. Pubmedid: 24854492.

  • Mellon EA, Springett GM, Hoffe SE, Hodul P, Malafa MP, Meredith KL, Fulp WJ, Zhao X, Shridhar R. Adjuvant radiotherapy and lymph node dissection in pancreatic cancer treated with surgery and chemotherapy. Cancer. 2014 Apr;120(8):1171-1177. Pubmedid: 24390779.

  • Hoffe S, Rao N, Shridhar R. Neoadjuvant vs Adjuvant Therapy for Resectable Pancreatic Cancer: The Evolving Role of Radiation. Semin Radiat Oncol. 2014 Apr;24(2):113-125. Pubmedid: 24635868.

  • Wong J, Rahman S, Saeed N, Lin HY, Almhanna K, Shridhar R, Hoffe S, Meredith KL. Effect of Body Mass Index in Patients Undergoing Resection for Gastric Cancer: A Single Center US Experience. J Gastrointest Surg. 2014 Mar;18(3):505-511. Pubmedid: 24443204.

  • Wong J, Rahman S, Saeed N, Lin HY, Almhanna K, Shridhar R, Hoffe S, Meredith KL. Prognostic impact of lymph node retrieval and ratio in gastric cancer: a u.s. Single center experience. J Gastrointest Surg. 2013 Dec;17(12):2059-2066. Pubmedid: 24129828.

  • Pimiento JM, Weber J, Hoffe SE, Shridhar R, Almhanna K, Vignesh S, Karl RC, Meredith KL. Outcomes associated with surgery for T4 esophageal cancer. Ann Surg Oncol. 2013 Aug;20(8):2706-2712. Pubmedid: 23504118.

  • Rao NG, Han G, Greene JN, Tanvetyanon T, Kish JA, De Conti RC, Chuong MD, Shridhar R, Biagioli MC, Caudell JJ, Trotti AM. Effect of prophylactic fluconazole on oral mucositis and candidiasis during radiation therapy for head-and-neck cancer. Pract Radiat Oncol. 2013 July;3(3):229-233. Pubmedid: 24674369.

  • Chuong MD, Springett GM, Freilich JM, Park CK, Weber JM, Mellon EA, Hodul PJ, Malafa MP, Meredith KL, Hoffe SE, Shridhar R. Stereotactic body radiation therapy for locally advanced and borderline resectable pancreatic cancer is effective and well tolerated. Int J Radiat Oncol Biol Phys. 2013 Jul;86(3):516-522. Pubmedid: 23562768.

  • Wong J, Weber J, Almhanna K, Hoffe S, Shridhar R, Karl R, Meredith KL. Extent of lymphadenectomy does not predict survival in patients treated with primary esophagectomy. J Gastrointest Surg. 2013 Jul;17(9):1562-1569. Pubmedid: 23818125.

  • Shridhar R, Weber J, Hoffe SE, Almhanna K, Karl R, Meredith K. Adjuvant Radiation Therapy and Lymphadenectomy in Esophageal Cancer: A SEER Database Analysis. J Gastrointest Surg. 2013 Jun;17(8):1339-1345. Pubmedid: 23749498.

  • Shridhar R, Almhanna K, Hoffe SE, Fulp W, Weber J, Chuong MD, Meredith KL. Increased survival associated with surgery and radiation therapy in metastatic gastric cancer: a Surveillance, Epidemiology, and End Results database analysis. Cancer. 2013 Jun;119(9):1636-1642. Pubmedid: 23361968.

  • Melis M, Weber J, Shridhar R, Hoffe S, Almhanna K, Karl RC, Meredith KL. Body mass index and perioperative complications after oesophagectomy for adenocarcinoma: a systematic database review. BMJ Open. 2013 May;3(5). Pubmedid: 23645908. Pmcid: PMC3646172.

  • Chuong MD, Fernandez DC, Shridhar R, Hoffe SE, Saini A, Hunt D, Meredith KL, Biagioli MC. High-dose-rate endorectal brachytherapy for locally advanced rectal cancer in previously irradiated patients. Brachytherapy. 2013 May;12(5):457-462. Pubmedid: 23707855.

  • Hernandez JM, Dimou F, Weber J, Almhanna K, Hoffe S, Shridhar R, Karl R, Meredith K. Defining the Learning Curve for Robotic-assisted Esophagogastrectomy. J Gastrointest Surg. 2013 May;17(8):1346-1351. Pubmedid: 23690208.

  • Wong JY, Shridhar R, Almhanna K, Hoffe SE, Karl RC, Meredith KL. The impact of body mass index on esophageal cancer. Cancer Control. 2013 Apr;20(2):138-143. Pubmedid: 23571704.

  • Almhanna K, Shridhar R, Meredith KL. Neoadjuvant or adjuvant therapy for resectable esophageal cancer: is there a standard of care?. Cancer Control. 2013 Apr;20(2):89-96. Pubmedid: 23571699.

  • Shridhar R, Hoffe SE, Almhanna K, Weber JM, Chuong MD, Karl RC, Meredith K. Lymph node harvest in esophageal cancer after neoadjuvant chemoradiotherapy. Ann Surg Oncol. 2013 Apr;20(9):3038-3043. Pubmedid: 23625142.

  • Almhanna K, Meredith KL, Hoffe SE, Shridhar R, Coppola D. Targeting the human epidermal growth factor receptor 2 in esophageal cancer. Cancer Control. 2013 Apr;20(2):111-116. Pubmedid: 23571701.

  • de la Fuente SG, Weber J, Hoffe SE, Shridhar R, Karl R, Meredith KL. Initial experience from a large referral center with robotic-assisted Ivor Lewis esophagogastrectomy for oncologic purposes. Surg Endosc. 2013 Apr;27(9):3339-3347. Pubmedid: 23549761.

  • Vignesh S, Hoffe SE, Meredith KL, Shridhar R, Almhanna K, Gupta AK. Endoscopic Therapy of Neoplasia Related to Barrett's Esophagus and Endoscopic Palliation of Esophageal Cancer. Cancer Control. 2013 Apr;20(2):117-129. Pubmedid: 23571702.

  • Saeed N, Latifi K, Hoffe SE, Cruz A, Opp DW, Moros EG, Zhang GG, Budzevich MM, Shridhar R, Dilling TJ. Optimizing Options for Re-irradiation With Deformable Image Registration of Prior Plans. Pract Radiat Oncol. 2013 April;3(2 Suppl 1):S16-S17. Pubmedid: 24674497.

  • Shridhar R, Almhanna K, Meredith KL, Biagioli MC, Chuong MD, Cruz A, Hoffe SE. Radiation therapy and esophageal cancer. Cancer Control. 2013 Apr;20(2):97-110. Pubmedid: 23571700.

  • Chuong MD, Freilich JM, Hoffe SE, Fulp W, Weber JM, Almhanna K, Dinwoodie W, Rao N, Meredith KL, Shridhar R. Intensity-Modulated Radiation Therapy vs. 3D Conformal Radiation Therapy for Squamous Cell Carcinoma of the Anal Canal. Gastrointest Cancer Res. 2013 Mar;6(2):39-45. Pubmedid: 23745158. Pmcid: PMC3674462.

  • Opfermann KJ, Wahlquist AE, Garrett-Mayer E, Shridhar R, Cannick L, Marshall DT. Adjuvant Radiotherapy and Lymph Node Status for Pancreatic Cancer: Results of a Study From the Surveillance, Epidemiology, and End Results (SEER) Registry Data. Am J Clin Oncol. 2012 Dec. Pubmedid: 23211221.

  • Shridhar R, Hayman T, Hoffe SE, Weber J, Almhanna K, Chuong M, Karl RC, Meredith KL. Body mass index and survival in esophageal adenocarcinoma treated with chemoradiotherapy followed by esophagectomy. J Gastrointest Surg. 2012 Jul;16(7):1296-1302. Pubmedid: 22399271.

  • Shridhar R, Dombi GW, Weber J, Hoffe SE, Meredith K, Konski A. Adjuvant radiation therapy increases overall survival in node-positive gastric cancer patients with aggressive surgical resection and lymph node dissection: a SEER database analysis. Am J Clin Oncol. 2012 Jun;35(3):216-221. Pubmedid: 21378540.

  • Dittrick GW, Weber JM, Shridhar R, Hoffe S, Melis M, Almhanna K, Barthel J, McLoughlin J, Karl RC, Meredith KL. Pathologic Nonresponders after Neoadjuvant Chemoradiation for Esophageal Cancer Demonstrate no Survival Benefit Compared with Patients Treated with Primary Esophagectomy. Ann Surg Oncol. 2012 May;19(5):1678-1684. Pubmedid: 22045465.

  • Robinson J, Opp D, Zhang G, Cashon K, Kozelka J, Hunt D, Walker L, Hoffe S, Shridhar R, Feygelman V. Evaluating dosimetric accuracy of flattening filter free compensator-based IMRT: Measurements with diode arrays. Med Phys. 2012 Jan;39(1):342. Pubmedid: 22225304.

  • Shridhar R, Dombi GW, Finkelstein SE, Meredith KL, Hoffe SE. Improved survival in patients with lymph node-positive gastric cancer who received preoperative radiation: an analysis of the Surveillance, Epidemiology, and End Results database. Cancer. 2011 Sep;117(17):3908-3916. Pubmedid: 21365627.

  • Chuong MD, Hayman TJ, Patel MR, Russell MS, Malafa MP, Hodul PJ, Springett GM, Choi J, Shridhar R, Hoffe SE. Comparison of 1-, 2-, and 3-Dimensional Tumor Response Assessment After Neoadjuvant GTX-RT in Borderline-Resectable Pancreatic Cancer. Gastrointest Cancer Res. 2011 Jul;4(4):128-134. Pubmedid: 22368736. Pmcid: PMC3283109.

  • Melis M, Weber JM, McLoughlin JM, Siegel EM, Hoffe S, Shridhar R, Turaga KK, Dittrick G, Dean EM, Karl RC, Meredith KL. An elevated body mass index does not reduce survival after esophagectomy for cancer. Ann Surg Oncol. 2011 Mar;18(3):824-831. Pubmedid: 20865331.

  • Hoffe SE, Finkelstein SE, Russell MS, Shridhar R. Nonsurgical options for hepatocellular carcinoma: evolving role of external beam radiotherapy. Cancer Control. 2010 Apr;17(1):100-110. Pubmedid: 20404793.

  • Shridhar R, Estabrook W, Yudelev M, Rakowski J, Burmeister J, Wilson GD, Joiner MC. Characteristic 8 keV X rays possess radiobiological properties of higher-LET radiation. Radiat Res. 2010 Mar;173(3):290-297. Pubmedid: 20199214.

  • Hoffe SE, Shridhar R, Biagioli MC. Radiation therapy for rectal cancer: current status and future directions. Cancer Control. 2010 Jan;17(1):25-34. Pubmedid: 20010516.

  • Shridhar R, Bolton S, Joiner MC, Forman JD. Dose Escalation Using a Hypofractionated, Intensity-Modulated Radiation Therapy Boost for Localized Prostate Cancer: Preliminary Results Addressing Concerns of High or Low alpha/beta Ratio. Clin Genitourin Cancer. 2009 Oct;7(3):E52-E57. Pubmedid: 19815482.

  • Chien J, Narita K, Rattan R, Giri S, Shridhar R, Staub J, Beleford D, Lai J, Roberts LR, Molina J, Kaufmann SH, Prendergast GC, Shridhar V. A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation. Oncogene. 2008 Dec;27(58):7223-7234. Pubmedid: 18806825.

  • Zhang J, Shridhar R, Dai Q, Song J, Barlow SC, Yin L, Sloane BF, Miller FR, Meschonat C, Li BD, Abreo F, Keppler D. Cystatin m: a novel candidate tumor suppressor gene for breast cancer. Cancer Res. 2004 Oct;64(19):6957-6964. Pubmedid: 15466187.

  • Shridhar R, Zhang J, Song J, Booth BA, Kevil CG, Sotiropoulou G, Sloane BF, Keppler D. Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells. Oncogene. 2004 Mar;23(12):2206-2215. Pubmedid: 14676833.

  • Shridhar V, Rivard S, Wang X, Shridhar R, Paisley C, Mullins C, Beirnat L, Dugan M, Sarkar F, Miller OJ, Vaitkevicius VK, Smith DI. Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer. Oncogene. 1997 May;14(18):2213-2216. Pubmedid: 9174057.

  • Wang L, Paradee W, Mullins C, Shridhar R, Rosati R, Wilke CM, Glover TW, Smith DI. Aphidicolin-induced FRA3B breakpoints cluster in two distinct regions. Genomics. 1997 May;41(3):485-488. Pubmedid: 9169152.

  • Shridhar V, Wang L, Rosati R, Paradee W, Shridhar R, Mullins C, Sakr W, Grignon D, Miller OJ, Sun QC, Petros J, Smith DI. Frequent breakpoints in the region surrounding FRA3B in sporadic renal cell carcinomas. Oncogene. 1997 Mar;14(11):1269-1277. Pubmedid: 9178887.

  • Shridhar R, Shridhar V, Rivard S, Siegfried JM, Pietraszkiewicz H, Ensley J, Pauley R, Grignon D, Sakr W, Miller OJ, Smith DI. Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck. Cancer Res. 1996 Dec;56(24):5576-5578. Pubmedid: 8971156.

  • Shridhar R, Shridhar V, Wang X, Paradee W, Dugan M, Sarkar F, Wilke C, Glover TW, Vaitkevicius VK, Smith DI. Frequent breakpoints in the 3p14.2 fragile site, FRA3B, in pancreatic tumors. Cancer Res. 1996 Oct;56(19):4347-4350. Pubmedid: 8813121.

  • Shridhar V, Rivard S, Shridhar R, Mullins C, Bostick L, Sakr W, Grignon D, Miller OJ, Smith DI. A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas. Oncogene. 1996 May;12(9):1931-1939. Pubmedid: 8649854.

  • Paradee W, Wilke CM, Wang L, Shridhar R, Mullins CM, Hoge A, Glover TW, Smith DI. A 350-kb cosmid contig in 3p14.2 that crosses the t(3;8) hereditary renal cell carcinoma translocation breakpoint and 17 aphidicolin-induced FRA3B breakpoints. Genomics. 1996 Jul;35(1):87-93. Pubmedid: 8661108.

  • Shridhar R, Imani-Shikhabadi R, Davis B, Streeter OA, Thomas CR. Curative treatment of esophageal cancer; an evidenced based review. J Gastrointest Cancer. 2013 Dec;44(4):375-384. Pubmedid: 23824628.

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