Philippe E. Spiess, MD

Where You Are:

Philippe E. Spiess, MD


For Consultation Requests or Referrals: (813) 745-8418


          •  Urology

          •  University of Texas MD Anderson Cancer Center, Houston, TX - Urologic Oncology

          •  McGill University, Montreal, Canada - Urology

          •  University of Toronto, Ontario, Canada - MD

  • Zargar H, Espiritu PN, Fairey AS, Mertens LS, Dinney CP, Mir MC, Krabbe LM, Cookson MS, Jacobsen NE, Gandhi NM, Griffin J, Montgomery JS, Vasdev N, Yu EY, Youssef D, Xylinas E, Campain NJ, Kassouf W, Dall'Era MA, Seah JA, Ercole CE, Horenblas S, Sridhar SS, McGrath JS, Aning J, Shariat SF, Wright JL, Thorpe AC, Morgan TM, Holzbeierlein JM, Bivalacqua TJ, North S, Barocas DA, Lotan Y, Garcia JA, Stephenson AJ, Shah JB, van Rhijn BW, Daneshmand S, Spiess PE, Black PC. Multicenter Assessment of Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer. Eur Urol. 2015 Feb;67(2):241-249. Pubmedid: 25257030.

  • Sharma P, Spiess PE. Penile cancer: Advanced penile cancer continues to elude systemic therapy. Nat Rev Urol. 2015 Feb. Pubmedid: 25708580.

  • Sharma P, Zargar-Shoshtari K, Caracciolo JT, Richard GJ, Poch MA, Pow-Sang J, Sexton WJ, Spiess PE. Sarcopenia as a predictor of complications in penile cancer patients undergoing inguinal lymph node dissection. World J Urol. 2015 Jan. Pubmedid: 25552207.

  • Zargar-Shoshtari K, Sharma P, Espiritu P, Kurian T, Pow-Sang JM, Mangar D, Sexton WJ, Spiess PE. Caval tumor thrombus volume influences outcomes in renal cell carcinoma with venous extension. Urol Oncol. 2014 Dec. Pubmedid: 25555854.

  • Zheng Y, Espiritu P, Hakky T, Jutras K, Spiess PE. Predicting ease of perinephric fat dissection at time of open partial nephrectomy using preoperative fat density characteristics. BJU Int. 2014 Dec;114(6):872-880. Pubmedid: 24274617.

  • Kim T, Zargar-Shoshtari K, Dhillon J, Lin HY, Yue B, Fishman M, Sverrisson EF, Spiess PE, Gupta S, Poch MA, Sexton WJ. Using Percentage of Sarcomatoid Differentiation as a Prognostic Factor in Renal Cell Carcinoma. Clin Genitourin Cancer. 2014 Dec. Pubmedid: 25544725.

  • Hegarty PK, Eardley I, Heidenreich A, McDougal WS, Minhas S, Spiess PE, Watkin N, Horenblas S. Penile cancer: organ-sparing techniques. BJU Int. 2014 Dec;114(6):799-805. Pubmedid: 24053403.

  • Davis SN, Sutton SK, Vadaparampil ST, Meade CD, Rivers BM, Patel MV, Torres-Roca JF, Heysek RV, Spiess P, Pow-Sang J, Jacobsen PB, Gwede CK. Informed decision making among first-degree relatives of prostate cancer survivors: A pilot randomized trial. Contemp Clin Trials. 2014 Nov;39(2):327-334. Pubmedid: 25465497. Pmcid: PMC4274628.

  • Zhao Y, Bui MM, Spiess PE, Dhillon J. Sclerosing PEComa of the Kidney: Clinicopathologic Analysis of 2 Cases and Review of the Literature. Clin Genitourin Cancer. 2014 Oct;12(5):e229-e232. Pubmedid: 25044147.

  • Baumgarten AS, Alhammali E, Hakky TS, Espiritu PN, Pow-Sang JM, Sexton WJ, Lockhart JL, Protzel C, Hakenberg O, Muneer A, Spiess PE. Salvage surgical resection for isolated locally recurrent inguinal lymph node metastasis of penile cancer: international study collaboration. J Urol. 2014 Sep;192(3):760-764. Pubmedid: 24603104.

  • Agarwal G, Gupta S, Spiess PE. Novel targeted therapies for the treatment of penile cancer. Expert Opin Drug Discov. 2014 Aug;9(8):959-968. Pubmedid: 24896220.

  • Russell CM, Espiritu PN, Kassouf W, Schwaab T, Buethe DD, Dhilon J, Sexton WJ, Poch M, Powsang JM, Tanguay S, Nayan M, Alsaadi H, Hanzly MI, Spiess PE. Surgical outcomes in the management of isolated nodal recurrences: a multicenter, international retrospective cohort. J Urol. 2014 Aug;192(2):350-356. Pubmedid: 24530987.

  • Rao SR, Moussly S, Pacheco M, Spiess PE, Sexton WJ. Identifying unrecognized collecting system entry and the integrity of repair during open partial nephrectomy: comparison of two techniques. Int Braz J Urol. 2014 Jul. Pubmedid: 24893916.

  • Sverrisson EF, Kim T, Espiritu PN, Sexton WJ, Pow-Sang JM, Dhillon J, Spiess PE. The merits of cytology in the workup for upper tract urothelial carcinoma - a contemporary review of a perplexing issue. Int Braz J Urol. 2014 Jul;40(4):493-498. Pubmedid: 25251966.

  • Espiritu PN, Sverrisson EF, Sexton WJ, Pow-Sang JM, Poch MA, Dhillon J, Spiess PE. Effect of tumor size on recurrence-free survival of upper tract urothelial carcinoma following surgical resection. Urol Oncol. 2014 Jul;32(5):619-624. Pubmedid: 24495448.

  • Gwede CK, Davis SN, Wilson S, Patel M, Vadaparampil ST, Meade CD, Rivers BM, Yu D, Torres-Roca J, Heysek R, Spiess PE, Pow-Sang J, Jacobsen P. Perceptions of Prostate Cancer Screening Controversy and Informed Decision Making: Implications for Development of a Targeted Decision Aid for Unaffected Male First-Degree Relatives. Am J Health Promot. 2014 Jun. Pubmedid: 24968183. Pmcid: PMC4277494.

  • Freilich JM, Spiess PE, Biagioli MC, Fernandez DC, Shi EJ, Hunt DC, Gupta S, Wilder RB. Lipiodol as a Fiducial Marker for Image-Guided Radiation Therapy for Bladder Cancer. Int Braz J Urol. 2014 May;40(2):190-197. Pubmedid: 24856485.

  • Strom TJ, Wilder RB, Fernandez DC, Mellon EA, Saini AS, Hunt DC, Pow-Sang JM, Spiess PE, Sexton WJ, Poch MA, Biagioli MC. A dosimetric study of polyethylene glycol hydrogel in 200 prostate cancer patients treated with high-dose rate brachytherapy?intensity modulated radiation therapy. Radiother Oncol. 2014 Apr;111(1):126-131. Pubmedid: 24746567.

  • Spiess PE. Reply: To PMID 24397943. Urology. 2014 Apr;83(4):950. Pubmedid: 24397942.

  • Protzel C, Spiess PE. Molecular research in penile cancer-lessons learned from the past and bright horizons of the future?. Int J Mol Sci. 2014 Apr;14(10):19494-19505. Pubmedid: 24077122. Pmcid: PMC3821569.

  • Baumgarten AS, Emtage JB, Wilder RB, Biagioli MC, Gupta S, Spiess PE. Intravesical lipiodol injection technique for image-guided radiation therapy for bladder cancer. Urology. 2014 Apr;83(4):946-950. Pubmedid: 24397940.

  • Baumgarten AS, Hakky TS, Carrion RE, Lockhart JL, Spiess PE. A Single-Institution Experience with Metallic Ureteral Stents: A Cost-Effective Method of Managing Deficiencies in Ureteral Drainage. Int Braz J Urol. 2014 Mar;40(2):225-231. Pubmedid: 24856490.

  • Hakky TS, Baumgarten AS, Allen B, Lin HY, Ercole CE, Sexton WJ, Spiess PE. Zonal NePhRO Scoring System: A Superior Renal Tumor Complexity Classification Model. Clin Genitourin Cancer. 2014 Feb;12(1):e13-e18. Pubmedid: 24120084.

  • Dhillon J, Mohanty SK, Kim T, Sexton WJ, Powsang J, Spiess PE. Spectrum of renal pathology in adult patients with congenital renal anomalies-a series from a tertiary cancer center. Ann Diagn Pathol. 2014 Feb;18(1):14-17. Pubmedid: 24321461.

  • Flaherty A, Kim T, Giuliano A, Magliocco A, Hakky TS, Pagliaro LC, Spiess PE. Implications for human papillomavirus in penile cancer. Urol Oncol. 2014 Jan;32(1):53.e1-53.e8. Pubmedid: 24239463.

  • Sverrisson EF, Espiritu PN, Spiess PE. New therapeutic targets in the management of urothelial carcinoma of the bladder. Res Rep Urol. 2014 Jan;5:53-65. Pubmedid: 24400235. Pmcid: PMC3826897.

  • Spiess PE, Levy DA, Pisters LL, Mouraviev V, Jones JS. Outcomes of salvage prostate cryotherapy stratified by pre-treatment PSA: update from the COLD registry. World J Urol. 2013 Dec;31(6):1321-1325. Pubmedid: 23179729.

  • Gupta S, Spiess PE. The prospects of pazopanib in advanced renal cell carcinoma. Ther Adv Urol. 2013 Oct;5(5):223-232. Pubmedid: 24082917. Pmcid: PMC3763778.

  • Agarwal G, Spiess PE. Prostate cancer: Focal cryotherapy freezes recurrent disease in its tracks. Nat Rev Urol. 2013 Oct;10(10):562-563. Pubmedid: 23979660.

  • Hakky TS, Ferguson D, Spiess PE, Bradley P, Lue TF, Carrion RE. Three-dimensional mapping and comparative analysis of the distal human corpus cavernosum and the inflatable penile prosthesis. Asian J Androl. 2013 Jul;15(4):567-570. Pubmedid: 23542138. Pmcid: PMC3739224.

  • Biagioli MC, Fernandez DC, Spiess PE, Wilder RB. Primary bladder preservation treatment for urothelial bladder cancer. Cancer Control. 2013 Jul;20(3):188-199. Pubmedid: 23811703.

  • Buethe DD, Spiess PE. Current management considerations for the incidentally detected small renal mass. Cancer Control. 2013 Jul;20(3):211-221. Pubmedid: 23811705.

  • Spiess PE, Horenblas S, Pagliaro LC, Biagioli MC, Crook J, Clark PE, Greenberg RE, Ercole CE. Current Concepts in Penile Cancer. J Natl Compr Canc Netw. 2013 May;11(5):617-624. Pubmedid: 23667210.

  • Hakky TS, Espiritu P, Rodriguez AR, Gould N, Spiess PE. Surgical management of a locally advanced symptomatic recurrence of penile sarcoma secondary to prostate brachytherapy. Int Braz J Urol. 2013 May;39(2):293-294. Pubmedid: 23683678.

  • Clark PE, Spiess PE, Agarwal N, Biagioli MC, Eisenberger MA, Greenberg RE, Herr HW, Inman BA, Kuban DA, Kuzel TM, Lele SM, Michalski J, Pagliaro L, Pal SK, Patterson A, Plimack ER, Pohar KS, Porter MP, Richie JP, Sexton WJ, Shipley WU, Small EJ, Trump DL, Wile G, Wilson TG, Dwyer M, Ho M. Penile cancer: Clinical Practice Guidelines in Oncology. J Natl Compr Canc Ne. 2013 May;11(5):594-615. Pubmedid: 23667209. Pmcid: PMC4042432.

  • Spiess PE. New treatment guidelines for penile cancer. J Natl Compr Canc Netw. 2013 May;11(5 Suppl):659-662. Pubmedid: 23704237.

  • Clark PE, Agarwal N, Biagioli MC, Eisenberger MA, Greenberg RE, Herr HW, Inman BA, Kuban DA, Kuzel TM, Lele SM, Michalski J, Pagliaro LC, Pal SK, Patterson A, Plimack ER, Pohar KS, Porter MP, Richie JP, Sexton WJ, Shipley WU, Small EJ, Spiess PE, Trump DL, Wile G, Wilson TG, Dwyer M, Ho M. Bladder cancer. J Natl Compr Canc Netw. 2013 Apr;11(4):446-475. Pubmedid: 23584347.

  • Spiess PE, Levy DA, Mouraviev V, Pisters LL, Jones JS. Predictors of biochemical failure in patients undergoing prostate whole-gland salvage cryotherapy: a novel risk stratification model. BJU Int. 2013 Mar;112(4):E256-E261. Pubmedid: 23469778.

  • Spiess PE. Editor's Comment. Int Braz J Urol. 2013 Jan;39(1):1-3. Pubmedid: 23489511.

  • Majewski T, Spiess PE, Bondaruk J, Black P, Clarke C, Benedict W, Dinney CP, Grossman HB, Tang KS, Czerniak B. Detection of bladder cancer using proteomic profiling of urine sediments. PLoS One. 2013 Jan;7(8):e42452. Pubmedid: 22879988. Pmcid: PMC3411788.

  • Spiess PE, Kurian T, Lin HY, Rawal B, Kim T, Sexton WJ, Pow-Sang JM. Preoperative metastatic status, level of thrombus and body mass index predict overall survival in patients undergoing nephrectomy and inferior vena cava thrombectomy. BJU Int. 2012 Dec;110(11 pt B):E470-E474. Pubmedid: 22519938.

  • Rao SR, Correa JJ, Sexton WJ, Pow-Sang JM, Dickinson SI, Lin HY, Spiess PE. Prospective clinical trial of the feasibility and safety of modified retroperitoneal lymph node dissection at time of nephroureterectomy for upper tract urothelial carcinoma. BJU Int. 2012 Dec;110(11 pt B):E475-E480. Pubmedid: 22564727.

  • Lawindy SM, Kurian T, Kim T, Mangar D, Armstrong PA, Alsina AE, Sheffield C, Sexton WJ, Spiess PE. Important surgical considerations in the management of renal cell carcinoma (RCC) with inferior vena cava (IVC) tumour thrombus. BJU Int. 2012 Oct;110(7):926-939. Pubmedid: 22540179.

  • Spiess PE, Buethe D. Reply. BJU Int. 2012 Oct;110(7):E328. Pubmedid: 22954032.

  • Buethe DD, Moussly S, Lin HY, Yue B, Rodriguez AR, Spiess PE, Sexton WJ. Is the R.E.N.A.L. nephrometry scoring system predictive of the functional efficacy of nephron sparing surgery in the solitary kidney?. J Urol. 2012 Sep;188(3):729-735. Pubmedid: 22819418.

  • Spiess PE, Given RW, Jones JS. Achieving the 'bifecta' using salvage cryotherapy for locally recurrent prostate cancer: analysis of the Cryo On-Line Data (COLD) Registry data. BJU Int. 2012 Jul;110(2):217-220. Pubmedid: 21992443.

  • Mouraviev V, Spiess PE, Jones JS. Salvage cryoablation for locally recurrent prostate cancer following primary radiotherapy. Eur Urol. 2012 Jun;61(6):1204-1211. Pubmedid: 22421081.

  • Rodriguez AR, Spiess PE. Editorial comment for park et Al. J Endourol. 2012 May;26(5):498. Pubmedid: 22214182.

  • Kumar N, Crocker T, Smith T, Pow-Sang J, Spiess PE, Egan K, Quinn G, Schell M, Sebti S, Kazi A, Chuang T, Salup R, Helal M, Zagaja G, Trabulsi E, McLarty J, Fazili T, Williams CR, Schreiber F, Slaton J, Anderson JK. Challenges and potential solutions to meeting accrual goals in a Phase II chemoprevention trial for prostate cancer. Contemp Clin Trials. 2012 Mar;33(2):279-285. Pubmedid: 22101219. Pmcid: PMC3268882.

  • Kumar N, Crocker T, Smith T, Pow-Sang J, Spiess PE, Connors S, Chornukur G, Dickinson SI, Bai W, Williams CR, Salup R, Fu W. Prostate Cancer Chemoprevention Targeting High Risk Populations: Model for Trial Design and Outcome Measures. J Cancer Sci Ther. 2012 Jan;2011(S3). Pubmedid: 22422102.

  • Kumar N, Crocker T, Smith T, Connors S, Pow-Sang J, Spiess PE, Egan K, Quinn G, Schell M, Sebti S, Kazi A, Chuang T, Salup R, Helal M, Zagaja G, Trabulsi E, McLarty J, Fazili T, Williams CR, Schreiber F, Anderson K. Prostate Cancer Chemoprevention Targeting Men with High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) and Atypical Small Acinar Proliferation (ASAP): Model for Trial Design and Outcome Measures. J Clin Trials. 2012 Jan;2(1). Pubmedid: 24533253. Pmcid: PMC3924733.

  • Kolla SB, Spiess PE, Sexton WJ. Interobserver reliability of the RENAL nephrometry scoring system. Urology. 2011 Sep;78(3):592-594. Pubmedid: 21782219.

  • Torrey R, Spiess PE, Pal SK, Josephson D. Role of surgery for locally advanced and metastatic renal cell carcinoma. J Natl Compr Canc Netw. 2011 Sep;9(9):985-993. Pubmedid: 21917623.

  • Motzer RJ, Agarwal N, Beard C, Bhayani S, Bolger GB, Carducci MA, Chang SS, Choueiri TK, Hancock SL, Hudes GR, Jonasch E, Josephson D, Kuzel TM, Levine EG, Lin DW, Margolin KA, Michaelson MD, Olencki T, Pili R, Ratliff TW, Redman BG, Robertson CN, Ryan CJ, Sheinfeld J, Spiess PE, Wang J, Wilder RB. Kidney cancer. J Natl Compr Canc Netw. 2011 Sep;9(9):960-977. Pubmedid: 21917622.

  • Lawindy SM, Rodriguez AR, Horenblas S, Spiess PE. Current and future strategies in the diagnosis and management of penile cancer. Adv Urol. 2011 May;2011:593751. Pubmedid: 21687574. Pmcid: PMC3113410.

  • Parker J, Spiess PE. Current and emerging bladder cancer urinary biomarkers. ScientificWorldJournal. 2011 May;11:1103-1112. Pubmedid: 21623456.

  • Ercole CE, Pow-Sang JM, Spiess PE. Update in the surgical principles and therapeutic outcomes of inguinal lymph node dissection for penile cancer. Urol Oncol. 2011 Apr;31(5):505-516. Pubmedid: 21481617.

  • Rodriguez AR, Hakky T, Spiess PE. Laparo-endoscopic single site retroperitoneal partial nephrectomy: a novel concept. Int Braz J Urol. 2011 Jan;37(1):136. Pubmedid: 21506441.

  • Kolla SB, Ercole C, Spiess PE, Pow-Sang JM, Sexton WJ. Nephron-sparing surgery for pathological stage T3b renal cell carcinoma confined to the renal vein. BJU Int. 2010 Nov;106(10):1494-1498. Pubmedid: 20230378.

  • Spiess PE, Fishman MN. Cytoreductive Nephrectomy vs Medical Therapy as Initial Treatment: A Rational Approach to the Sequence Question in Metastatic Renal Cell Carcinoma. Cancer Control. 2010 Oct;17(4):269-278. Pubmedid: 20861814.

  • Sexton WJ, Spiess PE, Pisters LL, Carpenter S, Madsen LT, Zagone R, Wang X, Troncoso P. Are there differences in zonal distribution and tumor volume of prostate cancer in patients with a positive family history?. Int Braz J Urol. 2010 Sep-Oct;36(5):571-582. Pubmedid: 21044374.

  • Wiegand LR, Hernandez M, Pisters LL, Spiess PE. Surgical management of lymph-node-positive prostate cancer: improves symptomatic control. BJU Int. 2010 Sep. Pubmedid: 20880197.

  • Parker J, Buga S, Sarria JE, Spiess PE. Advancements in the Management of Urologic Chronic Pelvic Pain: What is New and What Do We Know?. Curr Urol Rep. 2010 Jul;11(4):286-291. Pubmedid: 20449695.

  • Taylor JM, Spiess PE, Kassouf W, Munsell MF, Kamat AM, Dinney CP, Grossman HB, Pisters LL. Management of urethral recurrence after orthotopic urinary diversion. BJU Int. 2010 Jul;106(1):56-61. Pubmedid: 20002676.

  • Spiess PE, Katz AE, Chin JL, Bahn D, Cohen JK, Shinohara K, Hernandez M, Bossier J, Kassouf W, Pisters LL. A pretreatment nomogram predicting biochemical failure after salvage cryotherapy for locally recurrent prostate cancer. BJU Int. 2010 Jul;106(2):194-198. Pubmedid: 19922545.

  • Spiess PE. Editorial comment. Urology. 2010 Jun;75(6):1410-1411. Pubmedid: 20513502.

  • Childs MA, Wood CG, Spiess PE, Debiane LG, Hernandez M, Matin SF, Millikan RE, Siefker-Radtkie A, Scott SM, Pisters LL. Early results of chemotherapy with retroperitoneal lymph node dissection for isolated retroperitoneal recurrence of upper urinary tract urothelial carcinoma after nephroureterectomy. Can J Urol. 2010 Jun;17(3):5184-5189. Pubmedid: 20566011.

  • Spiess PE. Surgical management of locally recurrent renal cell carcinoma post-renal cryoablation: importance of stringent selection criteria. Urol Oncol. 2010 May-Jun;28(3):241-242. Pubmedid: 20189841.

  • Shinn EH, Swartz RJ, Thornton BB, Spiess PE, Pisters LL, Basen-Engquist KM. Testis cancer survivors' health behaviors: comparison with age-matched relative and demographically matched population controls. J Clin Oncol. 2010 May;28(13):2274-2279. Pubmedid: 20368572. Pmcid: PMC2860440.

  • Svatek RS, Munsell M, Kincaid JM, Hegarty P, Slaton JW, Busby JE, Gaston KE, Spiess PE, Pagliaro LC, Tamboli P, Pettaway CA. Association between lymph node density and disease specific survival in patients with penile cancer. J Urol. 2009 Dec;182(6):2721-2727. Pubmedid: 19837433.

  • Spiess PE. "Robotic cystectomy and the internet: separating fact from fiction" by Pruthi R.S. et al. Urol Oncol. 2009 Nov-Dec;27(6):686-. Pubmedid: 19879480.

  • Correa JJ, Fishman M, Chuang ST, Spiess PE. Surgery Plus Targeted Therapy for Renal Cell Carcinoma With Isolated Spermatic Cord Metastasis. Clin Genitourin Cancer. 2009 Oct;7(3):E101-E103. Pubmedid: 19815479.

  • Caso J, Seigne J, Back M, Spiess PE, Pow-Sang J, Sexton WJ. Circumferential resection of the inferior vena cava for primary and recurrent malignant tumors. J Urol. 2009 Sep;182(3):887-893. Pubmedid: 19616230.

  • Caso JR, Rodriguez AR, Correa J, Spiess PE. Update in the management of penile cancer. Int Braz J Urol. 2009 July;35(4):406-415. Pubmedid: 19719855.

  • Spiess PE, Hernandez MS, Pettaway CA. Contemporary inguinal lymph node dissection: minimizing complications. World J Urol. 2009 Apr;27 (2):205-212. Pubmedid: 18762945.

  • Gorbatiy V, Spiess PE, Pisters LL. The growing teratoma syndrome: Current review of the literature. Indian J Urol. 2009 Apr;25(2):186-189. Pubmedid: 19672343. Pmcid: PMC2710061.

  • Svatek R, Spiess P, Sundi D, Tu S, Tannir N, Brown G, Kamat A, Wood C, Pisters L. Long-term outcome for men with teratoma found at postchemotherapy retroperitoneal lymph node dissection. Cancer. 2009 Mar;115(6):1310-1317. Pubmedid: 19156903.

  • Williams DH 4th, Karpman E, Sander J, Spiess P, Pisters L, Lipshultz L. Pretreatment Semen Parameters in Men With Cancer. J Urol. 2009 Feb;181(2):736-740. Pubmedid: 19091343.

  • Spiess P, Pisters L, Liu P, Pettaway C, Kamat A, Gomez J, Tannir N. Malignant transformation of testicular teratoma: a chemoresistant phenotype. Urol Oncol. 2009 Jan;26(6):595-599. Pubmedid: 18367105. Pmcid: PMC4121060.

  • Park HS, Park WS, Bondaruk J, Tanaka N, Katayama H, Lee S, Spiess PE, Steinberg JR, Wang Z, Katz RL, Dinney C, Elias KJ, Lotan Y, Naeem RC, Baggerly K, Sen S, Grossman HB, Czerniak B. Quantitation of Aurora kinase A gene copy number in urine sediments and bladder cancer detection. J Natl Cancer Inst. 2008 Oct;100(19):1401-1411. Pubmedid: 18812553. Pmcid: PMC2720731.

  • Pettaway CA, Song R, Wang X, Sanchez-Ortiz R, Spiess PE, Strom S, Troncoso P. The ratio of matrix metalloproteinase to E-cadherin expression: a pilot study to assess mRNA and protein expression among African American prostate cancer patients. Prostate. 2008 Sep;68(13):1467-1476. Pubmedid: 18618693. Pmcid: PMC2574568.

  • Kassouf W, Spiess P, Brown G, Liu P, Grossman H, Dinney C, Kamat A. Prostatic urethral biopsy has limited usefulness in counseling patients regarding final urethral margin status during orthotopic neobladder reconstruction. J Urol. 2008 Jul;180(1):164-167. Pubmedid: 18485384.

  • Kassouf W, Agarwal P, Herr H, Munsell M, Spiess P, Brown G, Pisters L, Grossman H, Dinney C, Kamat A. Lymph node density is superior to TNM nodal status in predicting disease-specific survival after radical cystectomy for bladder cancer: analysis of pooled data from MDACC and MSKCC. J Clin Oncol. 2008 Jan;26(1):121-126. Pubmedid: 18165646.

  • Leibovici D, Spiess P, Heller L, Rodriguez-Bigas M, Chang G, Pisters L. Salvage surgery for locally recurrent prostate cancer after radiation therapy: tricks of the trade. Urol Oncol. 2008 Jan;26(1):9-16. Pubmedid: 18190824.

  • Spiess P, Busby J, Jordan J, Steinberg J, Bassett R, Davuluri R, Burt K, Troncoso P, Lee A, Taylor S, Pisters L. Can digital rectal examination or transrectal ultrasonography biopsy findings predict the side of nodal metastasis in prostate cancer. Urol Oncol. 2008 Jan;26(1):25-30. Pubmedid: 18190826.

  • Spiess P, Tannir N, Brown G, Liu P, Tu S, Evans J, Pisters L. Recurrence in nonseminomatous germ cell testis tumor patients with no viable tumor at postchemotherapy retroperitoneal lymph node dissection. Urology. 2007 Dec;70(6):1173-1178. Pubmedid: 18158041.

  • Spiess P, Tannir N, Tu S, Brown G, Liu P, Kamat A, Wood C, Evans J, Pisters L. Viable germ cell tumor at postchemotherapy retroperitoneal lymph node dissection: can we predict patients at risk of disease progression. Cancer. 2007 Dec;110(12):2700-2708. Pubmedid: 17948916.

  • Kassouf W, Spiess PE, Brown GA, Munsell MF, Grossman HB, Siefker-Radtke A, Dinney CP, Kamat AM. P0 stage at radical cystectomy for bladder cancer is associated with improved outcome independent of traditional clinical risk factors. Eur Urol. 2007 Dec;52(3):769-774. Pubmedid: 17434254. Pmcid: PMC2691552.

  • Spiess P, Pettaway C, Vakar-Lopez F, Kassouf W, Wang X, Busby J, Do K, Davuluri R, Tannir N. Treatment outcomes of small cell carcinoma of the prostate: a single-center study. Cancer. 2007 Oct;110(8):1729-1737. Pubmedid: 17786954.

  • Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, Wu X, Filipek S, McConkey D, Bar-Eli M, Issa JP, Benedict WF, Czerniak B. Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia. Proc Natl Acad Sci U S A. 2007 Oct;104(34):13732-13737. Pubmedid: 17702869. Pmcid: PMC1949496.

  • Kassouf W, Spiess PE, Siefker-Radtke A, Swanson D, Grossman HB, Kamat AM, Munsell MF, Guo CC, Czerniak BA, Dinney CP. Outcome and patterns of recurrence of nonbilharzial pure squamous cell carcinoma of the bladder: a contemporary review of The University of Texas M D Anderson Cancer Center experience. Cancer. 2007 Aug;110(4):764-769. Pubmedid: 17614317.

  • Spiess P, Izawa J, Bassett R, Kedar D, Busby J, Wong F, Eddings T, TamboliP, Pettaway C. Preoperative lymphoscintigraphy and dynamic sentinel node biopsy for staging penile cancer: results with pathological correlation. J Urol. 2007 Jun;177(6):2157-2161. Pubmedid: 17509308.

  • Spiess P, Tuziak T, Tibbs R, Bassett R, Tamboli P, Brown G, Grossman H, Ayala A, Czerniak B. Pseudosarcomatous and sarcomatous proliferations of the bladder. Hum Pathol. 2007 May;38(5):753-761. Pubmedid: 17306332.

  • Kassouf W, Sanchez-Ortiz R, Tamboli P, Jonasch E, Merchant M, Spiess P, WoodCG. Cytoreductive nephrectomy for T4NxM1 renal cell carcinoma: the M.D. Anderson Cancer Center experience. Urology. 2007 May;69(5):835-838. Pubmedid: 17482917.

  • Shinn EH, Basen-Engquist K, Thornton B, Spiess PE, Pisters L. Health behaviors and depressive symptoms in testicular cancer survivors. Urology. 2007 Apr;69(4):748-753. Pubmedid: 17445663. Pmcid: PMC2674069.

  • Bermejo C, Busby J, Spiess P, Heller L, Pagliaro L, Pettaway C. Neoadjuvant chemotherapy followed by aggressive surgical consolidation for metastatic penile squamous cell carcinoma. J Urol. 2007 Apr;177(4):1335-1338. Pubmedid: 17382727.

  • Spiess P, Kassouf W, Brown G, Kamat A, Liu P, Gomez J, Tu S, Tannir N, Pisters L. Surgical management of growing teratoma syndrome: the M. D. Anderson cancer center experience. J Urol. 2007 Apr;177(4):1330-1334. Pubmedid: 17382725.

  • Zorn K, Spiess P, Singh G, Orvieto M, Moore B, Corcos J. Long-term tensile properties of tension-free vaginal tape, suprapubic arc sling system and urethral sling in an in vivo rat model. J Urol. 2007 Mar;177(3):1195-1198. Pubmedid: 17296444.

  • Spiess P, Lee A, Busby J, Jordan J, Hernandez M, Burt K, Troncoso P, Merriman K, Pisters L. Surgically managed lymph node-positive prostate cancer: does delaying hormonal therapy worsen the outcome. Bju Int. 2007 Feb;99(2):321-325. Pubmedid: 17155975.

  • Spiess P, Brown G, Liu P, Tu S, Tannir N, Evans J, Kamat A, Kassouf W, Pisters L. Recurrence pattern and proposed surveillance protocol following post-chemotherapy retroperitoneal lymph node dissection. J Urol. 2007 Jan;177(1):131-138. Pubmedid: 17162023.

  • Tuziak T, Spiess P, Abrahams N, Wrona A, Tu S, Czerniak B. Multilocular cystadenoma and cystadenocarcinoma of the prostate. Urol Oncol. 2007 Jan;25(1):19-25. Pubmedid: 17208134.

  • Leibovici D, Spiess P, Agarwal P, Tu S, Pettaway C, Hitzhusen K, MillikanRE, Pisters L. Prostate cancer progression in the presence of undetectable or low serum prostate-specific antigen level. Cancer. 2007 Jan;109(2):198-204. Pubmedid: 17171704.

  • Spiess P, Kassouf W, Steinberg J, Tuziak T, Hernandez M, Tibbs R, CzerniakB, Kamat A, Dinney C, Grossman H. Review of the M.D. Anderson experience in the treatment of bladder sarcoma. Urol Oncol. 2007 Jan;25(1):38-45. Pubmedid: 17208137.

  • Spiess P, Brown G, Liu P, Tannir N, Tu S, Evans J, Czerniak B, Kamat A, Pisters L. Predictors of outcome in patients undergoing postchemotherapy retroperitoneal lymph node dissection for testicular cancer. Cancer. 2006 Oct;107(7):1483-1490. Pubmedid: 16944541.

  • Spiess P, Brown G, Pisters L, Liu P, Tu S, Evans J, Kamat A, Black P, Tannir N. Viable malignant germ cell tumor in the postchemotherapy retroperitoneal lymph node dissection specimen: can it be predicted using clinical parameters. Cancer. 2006 Oct;107(7):1503-1510. Pubmedid: 16944534.

  • Evans J, Spiess P, Kamat A, Wood C, Hernandez M, Pettaway C, Dinney C, Pisters L. Chylous ascites after post-chemotherapy retroperitoneal lymph node dissection: review of the M. D. Anderson experience. J Urol. 2006 Oct;176(4 Pt 1):1463-1467. Pubmedid: 16952661.

  • Spiess P, Grossman H. Fluorescence cystoscopy: is it ready for use in routine clinical practice. Curr Opin Urol. 2006 Sep;16(5):372-376. Pubmedid: 16905985.

  • Blehm KN, Spiess PE, Bondaruk JE, Dujka ME, Villares GJ, Zhao YJ, Bogler O, Aldape KD, Grossman HB, Adam L, McConkey DJ, Czerniak BA, Dinney CP, Bar-Eli M. Mutations within the kinase domain and truncations of the epidermal growth factor receptor are rare events in bladder cancer: implications for therapy. Clin Cancer Res. 2006 Aug;12(15):4671-4677. Pubmedid: 16899617.

  • Spiess P, Lee A, Leibovici D, Wang X, Do K, Pisters L. Presalvage prostate-specific antigen (PSA) and PSA doubling time as predictors of biochemical failure of salvage cryotherapy in patients with locally recurrent prostate cancer after radiotherapy. Cancer. 2006 Jul;107(2):275-280. Pubmedid: 16770783.

  • Spiess P, Czerniak B. Dual-track pathway of bladder carcinogenesis: practical implications. Arch Pathol Lab Med. 2006 Jun;130(6):844-852. Pubmedid: 16740038.

  • Zorn K, Spiess P, Ross P, Taguchi Y, Aprikian A. Resident involvement in open radical prostatectomy: a review of urology surgical training. Can J Urol. 2006 Jun;13(3):3164-3168. Pubmedid: 16813710.

  • Spiess P, Leibovici D, Pisters L. Surgery for locally advanced disease. Curr Urol Rep. 2006 May;7(3):209-216. Pubmedid: 16630524.

  • Spiess P, Kassouf W, Brown G, Highshaw R, Wang X, Do K, Kamat A, CzerniakB, Dinney C, Grossman H. Immediate versus staged urethrectomy in patients at high risk of urethral recurrence: is there a benefit to either approach?. Urology. 2006 Mar;67(3):466-471. Pubmedid: 16527559.

  • Taylor S, Merriman K, Spiess P, Pisters L. Inadequacies of the current American Joint Committee on cancer staging system for prostate cancer. Cancer. 2006 Feb;106(3):559-565. Pubmedid: 16369982.

  • Spiess P, Kassouf W, Tukaram K, Roy I. Metastatic umbilical mass from transitional cell carcinoma of the bladder. Can J Urol. 2005 Oct;12(5):2856-2858. Pubmedid: 16274525.

  • Spiess P, Tuziak T, Kassouf W, Grossman H, Czerniak B. Malignant mesothelioma of the tunica vaginalis. Urology. 2005 Aug;66(2):397-401. Pubmedid: 16040098.

  • Leibovici D, Lee A, Cheung R, Spiess P, Kuban D, Rosser C, Shen Y, YangY, Chichakli R, Pisters L. Symptomatic local recurrence of prostate carcinoma after radiation therapy. Cancer. 2005 May;103(10):2060-2066. Pubmedid: 15822114.

  • Zorn K, Spiess P, Salle J, Jednak R. Mucocolpos associated with bladder exstrophy: a case report. Can J Urol. 2005 Apr;12(2):2614-2615. Pubmedid: 15877945.

  • Spiess P, Rabah D, Herrera C, Singh G, Moore R, Corcos J. The tensile properties of tension-free vaginal tape and cadaveric fascia lata in an in vivo rat model. Bju Int. 2004 Jan;93(1):171-173. Pubmedid: 14678391.

  • Rabah D, Spiess P, Begin L, Corcos J. Tissue reaction of the rabbit urinary bladder to tension-free vaginal tape and porcine small intestinal submucosa. Bju Int. 2002 Oct;90(6):601-606. Pubmedid: 12230625.

  • Spiess P, Capolicchio J, Kiruluta G, Salle J, Berardinucci G, Corcos J. Is an artificial sphincter the best choice for incontinent boys with Spina Bifida? Review of our long term experience with the AS-800 artificial sphincter. Can J Urol. 2002 Apr;9(2):1486-1491. Pubmedid: 12010593.

  • Nam R, Redelmeier D, Spiess P, Sampson H, Fradet Y, Jewett M. Comparison of molecular and conventional strategies for followup of superficial bladder cancer using decision analysis. J Urol. 2000 Mar;1(3):752-757. Pubmedid: 10687970.

  • Spiess P, Dion S, Zvara P, Merlin S, Chan P, Brock G. 7-Nitroindazole: a selective inhibitor of penile erection: an in vivo study in a rat animal model. Urology. 1996 Jan;47(1):93-96. Pubmedid: 8560670 .

  • Zvara P, Spiess P, Merlin S, Begin L, Brock G. Neurogenic erectile dysfunction: the course of nicotinamide adenine dinucleotide phosphate diaphorase-positive nerve fibers on the surface of the prostate. Urology. 1996 Jan;47(1):146-151. Pubmedid: 8560654 .

  • Hakky T, Kim T, Rodriguez AR, Armstrong P, Mangar D, Spiess PE. Retroperitoneal lymph node dissection with concomitant IVC thrombectomy, caval wall resection, and grafting for metastatic NSGCT. Int Braz J Urol. 38(1):135. Pubmedid: 22397783.

  • Spiess PE. Editor's Comment. Int Braz J Urol. 40(1):1-2. Pubmedid: 24642145.

  • Rao SR, Moussly S, Pacheco M, Spiess PE, Sexton WJ. Identifying unrecognized collecting system entry and the integrity of repair during open partial nephrectomy: comparison of two techniques. Int Braz J Urol. 40(5):637-643. Pubmedid: 25498274.

  • Spiess PE, Tannir NM. Reply. Urol Oncol. 27(2):218-219. Pubmedid: 19285239.

  • Spiess PE, Correa JJ. Robotic assisted laparoscopic partial cystectomy and urachal resection for urachal adenocarcinoma. Int Braz J Urol. 2009 Sept;35(5):609. Pubmedid: 19860941.

  • Wallen JJ, Baumgarten AS, Kim T, Hakky TS, Carrion RE, Spiess PE. Optimizing penile length in patients undergoing partial penectomy for penile cancer: novel application of the ventral phalloplasty oncoplastic technique. Int Braz J Urol. 40(5):708-709. Pubmedid: 25498284.

Dr. Philippe Spiess is a genitourinary oncologist at Moffitt Cancer Center and an assistant professor of oncology and urology at the University of South Florida College of Medicine.

Dr. Spiess’ research interests include novel therapies for advanced renal and prostate cancer.  He is widely published and has authored several books and book chapters on urologic cancers.  In addition, he is a reviewer for numerous professional journals, including the International Journal of Urology and serves on the editorial board of the International Brazilian Journal of Urology. Dr. Spiess is also a reviewer for the American Urological Association Prostate and Bladder Cancer webinars.

A native of Canada, Dr. Spiess received a master’s in experimental urology surgery at McGill University in Montreal and a medical degree from the University of Toronto.  He completed a urology residency at McGill University and a urologic oncology fellowship at University of Texas MD Anderson Cancer Center.

Dr. Spiess is a fellow of the Royal College of Physicians and Surgeons in Canada and a member of the Société Internationale d'Urologie.  He is fluent in English and French.


TOOLS:   Font Size small font resizer separator font resizer separator big font resizer
 |  Site Map  |  Privacy Policy  |  Terms and Conditions