Claudio Anasetti, MD

Where You Are:

Claudio Anasetti, MD

Medical Oncology

For Consultation Requests or Referrals: (888) 663-3488

 
 

BOARD CERTIFICATION:
          •  Medical Oncology

FELLOWSHIP:
          •  University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA - Oncology
          •  Children's Memorial Hospital, Oklahoma City - Immunology

RESIDENCY:
          •  University of Perugia, Italy - Internal Medicine

MEDICAL SCHOOL:
          •  University of Perugia, Italy - School of Medicine

  • Eapen M, Logan BR, Appelbaum FR, Antin JH, Anasetti C, Couriel DR, Chen J, Maziarz RT, McCarthy PL, Nakamura R, Ratanatharathorn V, Vij R, Champlin RE. Long-term Survival after Transplantation of Unrelated Donor Peripheral Blood or Bone Marrow Hematopoietic Cells for Hematologic Malignancy. Biol Blood Marrow Tr. 2014 Sep. Pubmedid: 25255165.

  • Pidala J, Lee SJ, Ahn KW, Spellman S, Wang HL, Aljurf M, Askar M, Dehn J, Fernandez Vi?a M, Gratwohl A, Gupta V, Hanna R, Horowitz MM, Hurley CK, Inamoto Y, Kassim AA, Nishihori T, Mueller C, Oudshoorn M, Petersdorf EW, Prasad V, Robinson J, Saber W, Schultz KR, Shaw B, Storek J, Wood WA, Woolfrey AE, Anasetti C. Non-permissive -DPB1 mismatch among otherwise HLA-matched donor-recipient pairs results in increased overall mortality after myeloablative unrelated allogeneic hematopoietic cell transplantation for hematologic malignancies. Blood. 2014 Aug. Pubmedid: 25161269.

  • Waller EK, Logan BR, Harris WA, Devine SM, Porter DL, Mineishi S, McCarty JM, Gonzalez CE, Spitzer TR, Krijanovski OI, Linenberger ML, Woolfrey A, Howard A, Wu J, Confer DL, Anasetti C. Improved Survival After Transplantation of More Donor Plasmacytoid Dendritic or Na?ve T Cells From Unrelated-Donor Marrow Grafts: Results From BMTCTN 0201. J Clin Oncol. 2014 Aug;32(22):2365-2372. Pubmedid: 24982459.

  • Nishihori T, Perkins J, Mishra A, Komrokji R, Kim J, Kharfan-Dabaja MA, Perez L, Lancet J, Fernandez H, List A, Anasetti C, Field T. Pretransplantation 5-azacitidine in high-risk myelodysplastic syndrome. Biol Blood Marrow Tr. 2014 Jun;20(6):776-780. Pubmedid: 24534108.

  • Chavez JC, Kharfan-Dabaja MA, Kim J, Yue B, Dalia S, Pinilla-Ibarz J, Anasetti C, Locke FL. Genomic aberrations deletion 11q and deletion 17p independently predict for worse progression-free and overall survival after allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia. Leuk Res. 2014 Apr. Pubmedid: 24889511.

  • Betts BC, Veerapathran A, Pidala J, Yu XZ, Anasetti C. STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity. J Leukoc Biol. 2014 Feb;95(2):205-213. Pubmedid: 24068731. Pmcid: PMC3896660.

  • Kunter G, Perkins JB, Pidala J, Nishihori T, Kharfan-Dabaja MA, Field T, Fernandez H, Perez L, Locke F, Ayala E, Tomblyn M, Ochoa-Bayona JL, Betts B, Nieder M, Anasetti C. Pharmacokinetically-targeted BU and fludarabine as conditioning before allogeneic hematopoietic cell transplantation for adults with ALL in first remission. Bone Marrow Transplant. 2014 Jan;49(1):11-16. Pubmedid: 23995098.

  • Switzer GE, Bruce JG, Harrington D, Haagenson M, Drexler R, Foley A, Confer D, Bishop M, Anderlini P, Rowley S, Leitman SF, Anasetti C, Wingard JR. Health-related quality of life of bone marrow versus peripheral blood stem cell donors: a prespecified subgroup analysis from a phase III RCT-BMTCTN protocol 0201. Biol Blood Marrow Tran. 2014 Jan;20(1):118-127. Pubmedid: 24184336.

  • Eapen M, Klein JP, Ruggeri A, Spellman S, Lee SJ, Anasetti C, Arcese W, Barker JN, Baxter-Lowe LA, Brown M, Fernandez-Vina MA, Freeman J, He W, Paolo Iori A, Horowitz MM, Locatelli F, Marino S, Maiers M, Michel G, Sanz GF, Gluckman E, Rocha V. Impact of allele-level HLA matching on outcomes after myeloablative single unit umbilical cord blood transplantation for hematologic malignancy. Blood. 2014 Jan;123(1):133-140. Pubmedid: 24141369. Pmcid: PMC3879902.

  • Pidala J, Wang T, Haagenson M, Spellman SR, Askar M, Battiwalla M, Baxter-Lowe LA, Bitan M, Fernandez-Vi?a M, Gandhi M, Jakubowski AA, Maiers M, Marino SR, Marsh SG, Oudshoorn M, Palmer J, Prasad VK, Reddy V, Ringden O, Saber W, Santarone S, Schultz KR, Setterholm M, Trachtenberg E, Turner EV, Woolfrey AE, Lee SJ, Anasetti C. Amino acid substitution at peptide-binding pockets of HLA class I molecules increases risk of severe acute GVHD and mortality. Blood. 2013 Nov;122(22):3651-3658. Pubmedid: 23982174. Pmcid: PMC3837514.

  • Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ. Pharmacologic inhibition of PKC? and PKC? prevents GVHD while preserving GVL activity in mice. Blood. 2013 Oct;122(14):2500-2511. Pubmedid: 23908466. Pmcid: PMC3790515.

  • Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ. c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice. Eur J Immunol. 2013 Sep;43(9):2327-2337. Pubmedid: 23716202. Pmcid: PMC3940138.

  • Veerapathran A, Pidala J, Beato F, Betts B, Kim J, Turner JG, Hellerstein MK, Yu XZ, Janssen W, Anasetti C. Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease. Blood. 2013 Sep;122(13):2251-2261. Pubmedid: 23908471. Pmcid: PMC3785121.

  • Wang D, Yu Y, Haarberg K, Fu J, Kaosaard K, Nagaraj S, Anasetti C, Gabrilovich D, Yu XZ. Dynamic change and impact of myeloid-derived suppressor cells in allogeneic bone marrow transplantation in mice. Biol Blood Marrow Tr. 2013 May;19(5):692-702. Pubmedid: 23376089. Pmcid: PMC4011929.

  • Kharfan-Dabaja MA, Anasetti C, Fernandez HF, Perkins J, Ochoa-Bayona JL, Pidala J, Perez LE, Ayala E, Field T, Alsina M, Nishihori T, Locke F, Pinilla-Ibarz J, Tomblyn M. Phase II Study of CD4(+)-Guided Pentostatin Lymphodepletion and Pharmacokinetically Targeted Busulfan as Conditioning for Hematopoietic Cell Allografting. Biol Blood Marrow Transplant. 2013 May;19(7):1087-1093. Pubmedid: 23632090.

  • Fern?ndez-Vi?a MA, Klein JP, Haagenson M, Spellman SR, Anasetti C, Noreen H, Baxter-Lowe LA, Cano P, Flomenberg N, Confer DL, Horowitz MM, Oudshoorn M, Petersdorf EW, Setterholm M, Champlin R, Lee SJ, de Lima M. Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation. Blood. 2013 May;121(22):4603-4610. Pubmedid: 23596045. Pmcid: PMC3668493.

  • Nishihori T, Ochoa-Bayona JL, Kim J, Pidala J, Shain K, Baz R, Sullivan D, Jim HS, Anasetti C, Alsina M. Allogeneic hematopoietic cell transplantation for consolidation of VGPR or CR for newly diagnosed multiple myeloma. Bone Marrow Transplant. 2013 Apr;48(9):1179-1184. Pubmedid: 23542223.

  • Pidala J, Kim J, Schell M, Lee SJ, Hillgruber R, Nye V, Ayala E, Alsina M, Betts B, Bookout R, Fernandez HF, Field T, Locke FL, Nishihori T, Ochoa JL, Perez L, Perkins J, Shapiro J, Tate C, Tomblyn M, Anasetti C. Race/ethnicity affects the probability of finding an HLA-A, -B, -C and -DRB1 allele-matched unrelated donor and likelihood of subsequent transplant utilization. Bone Marrow Transplant. 2013 Mar;48(3):346-350. Pubmedid: 22863723.

  • Yu Y, Cho HI, Wang D, Kaosaard K, Anasetti C, Celis E, Yu XZ. Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms. J Immunol. 2013 Feb;190(4):1873-1881. Pubmedid: 23315072. Pmcid: PMC3563723.

  • Pidala J, Craig BM, Lee SJ, Majhail N, Quinn G, Anasetti C. Practice variation in physician referral for allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2013 Jan;48(1):63-67. Pubmedid: 22705801. Pmcid: PMC3549547.

  • Denzen EM, Majhail NS, Stickney Ferguson S, Anasetti C, Bracey A, Burns L, Champlin R, Chell J, Leather H, Lill M, Maziarz RT, Medoff E, Neumann J, Schmit-Pokorny K, Snyder EL, Wiggins L, Yolin Raley DS, Murphy EA. Hematopoietic cell transplantation in 2020: summary of year 2 recommendations of the National Marrow Donor Program's System Capacity Initiative. Biol Blood Marrow Tran. 2013 Jan;19(1):4-11. Pubmedid: 23078785. Pmcid: PMC3617925.

  • Anasetti C, Logan BR, Confer DL. Peripheral-blood versus bone marrow stem cells. N Engl J Med. 2013 Jan;368(3):288. Pubmedid: 23323911.

  • Janssen WE, Rahn D, Hackett M, Coyle D, Tomblyn M, Smilee RC, Anasetti C, Fernandez HF. Apheresis and transplant of hematopoietic progenitor cells (HPC) from allogeneic donors of age above 60 years. Bone Marrow Transplant. 2012 Dec;47(12):1520-1525. Pubmedid: 22562079.

  • Pidala J, Kim J, Jim H, Kharfan-Dabaja MA, Nishihori T, Fernandez HF, Tomblyn M, Perez L, Perkins J, Xu M, Janssen WE, Veerapathran A, Betts BC, Locke FL, Ayala E, Field T, Ochoa L, Alsina M, Anasetti C. A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation. Haematologica. 2012 Dec;97(12):1882-1889. Pubmedid: 22689677.

  • Foley B, Cooley S, Verneris MR, Curtsinger J, Luo X, Waller EK, Anasetti C, Weisdorf D, Miller JS. Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen. J Immunol. 2012 Nov;189(10):5082-5088. Pubmedid: 23077239. Pmcid: PMC3490031.

  • Boucher K, Parquet N, Widen R, Shain K, Baz R, Alsina M, Koomen J, Anasetti C, Dalton W, Perez LE. Stemness of B-cell progenitors in multiple myeloma bone marrow. Clin Cancer Res. 2012 Nov;18(22):6155-6168. Pubmedid: 22988056. Pmcid: PMC3500436.

  • Anasetti C, Logan BR, Lee SJ, Waller EK, Weisdorf DJ, Wingard JR, Cutler CS, Westervelt P, Woolfrey A, Couban S, Ehninger G, Johnston L, Maziarz RT, Pulsipher MA, Porter DL, Mineishi S, McCarty JM, Khan SP, Anderlini P, Bensinger WI, Leitman SF, Rowley SD, Bredeson C, Carter SL, Horowitz MM, Confer DL. Peripheral-blood stem cells versus bone marrow from unrelated donors. N Engl J Med. 2012 Oct;367(16):1487-1496. Pubmedid: 23075175. Pmcid: PMC3816375.

  • Pidala J, Perez L, Beato F, Anasetti C. Ustekinumab demonstrates activity in glucocorticoid-refractory acute GVHD. Bone Marrow Transplant. 2012 Sep;47(5):747-748. Pubmedid: 21874061.

  • Wang D, Iclozan C, Liu C, Xia C, Anasetti C, Yu XZ. LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice. Biol Blood Marrow Tran. 2012 Aug;18(8):1182-1190.e1. Pubmedid: 22698484. Pmcid: PMC3417119.

  • Yu Y, Yu J, Iclozan C, Kaosaard K, Anasetti C, Yu XZ. Bim is required for T-cell allogeneic responses and graft-versus-host disease in vivo. Am J Blood Res. 2012 Aug;2(1):77-85. Pubmedid: 22432091. Pmcid: PMC3301434.

  • Perkins JB, Shapiro JF, Bookout RN, Yee GC, Anasetti C, Janssen WE, Fernandez HF. Retrospective comparison of filgrastim plus plerixafor to other regimens for remobilization after primary mobilization failure: clinical and economic outcomes. Am J Hematol. 2012 Jul;87(7):673-677. Pubmedid: 22674468.

  • Perkins JB, Kim J, Anasetti C, Fernandez HF, Perez LE, Ayala E, Kharfan-Dabaja MA, Tomblyn MR, Sullivan DM, Pidala JA, Field TL. Maximally tolerated busulfan systemic exposure in combination with fludarabine as conditioning before allogeneic hematopoietic cell transplantation. Biol Blood Marrow Tran. 2012 Jul;18(7):1099-1107. Pubmedid: 22198540.

  • Weisdorf D, Cooley S, Devine S, Fehniger TA, Dipersio J, Anasetti C, Waller EK, Porter D, Farag S, Drobyski W, Defor T, Haagenson M, Curtsinger J, Miller J. T cell-depleted partial matched unrelated donor transplant for advanced myeloid malignancy: KIR ligand mismatch and outcome. Biol Blood Marrow Tran. 2012 Jun;18(6):937-943. Pubmedid: 22155505. Pmcid: PMC3319849.

  • Nishihori T, Alekshun TJ, Shain K, Sullivan DM, Baz R, Perez L, Pidala J, Kharfan-Dabaja MA, Ochoa-Bayona JL, Fernandez HF, Yarde DN, Oliveira V, Fulp W, Han G, Kim J, Chen DT, Raychaudhuri J, Dalton W, Anasetti C, Alsina M. Bortezomib salvage followed by a Phase I/II study of bortezomib plus high-dose melphalan and tandem autologous transplantation for patients with primary resistant myeloma. Brit J Haematol. 2012 Jun;157(5):553-563. Pubmedid: 22449149. Pmcid: PMC4030553.

  • Anasetti C. The ever elusive permissive mismatch. Biol Blood Marrow Transplant. 2012 May;18(5):657-658. Pubmedid: 22449608.

  • Kumar A, Mhaskar AR, Reljic T, Mhaskar RS, Kharfan-Dabaja MA, Anasetti C, Mohty M, Djulbegovic B. Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: a systematic review. Leukemia. 2012 Apr;26(4):582-588. Pubmedid: 22182922.

  • Pidala J, Kim J, Anasetti C, Nishihori T, Betts B, Field T, Perkins J. The global severity of chronic graft-versus-host disease, determined by National Institutes of Health consensus criteria, is associated with overall survival and non-relapse mortality. Haematologica. 2012 Feb;96(11):1678-1684. Pubmedid: 21791465. Pmcid: PMC3208686.

  • Majhail NS, Murphy EA, Denzen EM, Ferguson SS, Ferguson SS, Anasetti C, Bracey A, Burns L, Champlin R, Hubbard N, Markowitz M, Maziarz RT, Medoff E, Neumann J, Schmit-Pokorny K, Weisdorf DJ, Yolin Raley DS, Chell J, Snyder EL. The National Marrow Donor Program's Symposium on Hematopoietic Cell Transplantation in 2020: a health care resource and infrastructure assessment. Biol Blood Marrow Transplant. 2012 Feb;18(2):172-182. Pubmedid: 22178961.

  • Anasetti C, Aversa F, Brunstein CG. Back to the future: mismatched unrelated donor, haploidentical related donor, or unrelated umbilical cord blood transplantation?. Biol Blood Marrow Transplant. 2012 Jan;18(1 Suppl):S161-S165. Pubmedid: 22226100.

  • Eapen M, Klein JP, Sanz GF, Spellman S, Ruggeri A, Anasetti C, Brown M, Champlin RE, Garcia-Lopez J, Hattersely G, Koegler G, Laughlin MJ, Michel G, Nabhan SK, Smith FO, Horowitz MM, Gluckman E, Rocha V. Effect of donor-recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis. Lancet Oncol. 2011 Dec;12(13):1214-1221. Pubmedid: 21982422. Pmcid: PMC3245836.

  • Perez L, Anasetti C, Pidala J. Have we improved in preventing and treating acute graft-versus-host disease?. Curr Opin Hematol. 2011 Nov;18(6):408-413. Pubmedid: 21912253. Pmcid: PMC3432261.

  • Yu Y, Wang D, Liu C, Kaosaard K, Semple K, Anasetti C, Yu XZ. Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and ROR?t in mice. Blood. 2011 Nov;118(18):5011-5020. Pubmedid: 21856864. Pmcid: PMC3208306.

  • Veerapathran A, Pidala J, Beato F, Yu XZ, Anasetti C. Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly. Blood. 2011 Nov;118(20):5671-5680. Pubmedid: 21948174. Pmcid: PMC3217366.

  • Pidala J, Djulbegovic B, Anasetti C, Kharfan-Dabaja M, Kumar A. Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission. Cochrane Database Syst Rev. 2011 Nov;(10):CD008818. Pubmedid: 21975786.

  • Perkins J, Field T, Kim J, Kharfan-Dabaja MA, Ayala E, Perez L, Fernandez H, Fancher K, Tate C, Shaw LM, Milone MC, Gardiner JA, Miller S, Anasetti C. Pharmacokinetic targeting of i.v. BU with fludarabine as conditioning before hematopoietic cell transplant: the effect of first-dose area under the concentration time curve on transplant-related outcomes. Bone Marrow Transplant. 2011 Nov;46(11):1418-1425. Pubmedid: 21132026.

  • Pidala J, Lee SJ, Quinn G, Jim H, Kim J, Anasetti C. Variation in management of immune suppression after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2011 Oct;17(10):1528-1536. Pubmedid: 21440079.

  • Santarone S, Pidala J, Di Nicola M, Field T, Alsina M, Ayala E, Janssen W, Kharfan-Dabaja MA, Ochoa L, Perez L, Perkins J, Raychaudhuri J, Fernandez H, Anasetti C. Fludarabine and pharmacokinetic-targeted busulfan before allografting for adults with acute lymphoid leukemia. Biol Blood Marrow Tran. 2011 Oct;17(10):1505-1511. Pubmedid: 21385623.

  • Pidala J, Tomblyn M, Nishihori T, Field T, Ayala E, Perkins J, Fernandez H, Locke F, Perez L, Ochoa JL, Alsina M, Anasetti C. Sirolimus demonstrates activity in the primary therapy of acute graft-versus-host disease without systemic glucocorticoids. Haematologica. 2011 Sep;96(9):1351-1356. Pubmedid: 21565902. Pmcid: PMC3166106.

  • Pidala J, Tomblyn M, Nishihori T, Ayala E, Field T, Fernandez H, Perez L, Locke F, Alsina M, Ochoa JL, Perkins J, Tate C, Shapiro J, Conwell M, Bookout R, Anasetti C. ATG Prevents Severe Acute Graft-versus-Host Disease in Mismatched Unrelated Donor Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2011 Aug;17(8):1237-1244. Pubmedid: 21215811.

  • Woolfrey A, Klein JP, Haagenson M, Spellman S, Petersdorf E, Oudshoorn M, Gajewski J, Hale GA, Horan J, Battiwalla M, Marino SR, Setterholm M, Ringden O, Hurley C, Flomenberg N, Anasetti C, Fernandez-Vina M, Lee SJ. HLA-C antigen mismatch is associated with worse outcome in unrelated donor peripheral blood stem cell transplantation. Biol Blood Marrow Tr. 2011 Jun;17(6):885-892. Pubmedid: 20870028. Pmcid: PMC3071866.

  • Pidala J, Kim J, Anasetti C, Kharfan-Dabaja MA, Field T, Perkins J, Ayala E, Perez L, Fernandez H. Targeted i.v. BU and fludarabine (t-i.v. BU/Flu) provides effective control of AML in adults with reduced toxicity. Bone Marrow Transplant. 2011 May;46(5):641-649. Pubmedid: 20711242.

  • Kharfan-Dabaja MA, Chavez JC, Yu D, Zhu W, Fernandez-Vertiz EI, Perkins J, Shapiro J, Bookout R, Perez L, Fernandez HF, Komrokji RS, Lancetf J, Brand L, Field T, Ayala E, Janssen W, List AF, Anasetti C. Severe hypoalbuminemia at day 90 predicts worse nonrelapse mortality and overall survival after allogeneic hematopoietic stem cell transplantation for acute myelogenous leukemia and myelodysplastic syndrome. Biol Blood Marrow Tran. 2011 Mar;17(3):384-393. Pubmedid: 20655389.

  • Semple K, Nguyen A, Yu Y, Wang H, Anasetti C, Yu XZ. Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling. Blood. 2011 Mar;117(11):3096-3103. Pubmedid: 21245484. Pmcid: PMC3062312.

  • Semple K, Yu Y, Wang D, Anasetti C, Yu XZ. Efficient and selective prevention of GVHD by antigen-specific induced Tregs via linked-suppression in mice. Biol Blood Marrow Tran. 2011 Mar;17(3):309-318. Pubmedid: 21224010. Pmcid: PMC3039088.

  • Cutler C, Kesselheim A, Gabardi S, Andersson BS, Carpenter P, Khoury HJ, Litzow M, Rowley SD, Lanum S, Leather H, Tina Shih YC, Gale RP, Wingard JR, Appelbaum FR, Anasetti C. Generic immunosuppressants in hematopoietic cell transplantation. Biol Blood Marrow Tran. 2011 Mar;17(3):285-290. Pubmedid: 21087678.

  • Pidala J, Roman-Diaz J, Kim J, Nishihori T, Perkins J, Tate C, Ochoa-Bayona JL, Field T, Fernandez HF, Tomblyn M, Ayala E, Anasetti C, Kharfan-Dabaja MA. Targeted IV busulfan and fludarabine followed by post-allogeneic hematopoietic cell transplantation rituximab demonstrate encouraging activity in CD20+ lymphoid malignancies without increased risk of infectious complications. Int J Hematol. 2011 Feb;93(2):206-212. Pubmedid: 21246311.

  • Pidala J, Kim J, Kharfan-Dabaja MA, Nishihori T, Field T, Perkins J, Perez L, Fernandez H, Anasetti C. Dysglycemia following glucocorticoid therapy for acute graft-versus-host disease adversely affects transplantation outcomes. Biol Blood Marrow Tran. 2011 Feb;17(2):239-248. Pubmedid: 20637884.

  • Pidala J, Kim J, Anasetti C, Kharfan-Dabaja MA, Nishihori T, Field T, Perkins J, Perez L, Fernandez HF. Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia. J Hematol Oncol. 2011 Jan;3:36. Pubmedid: 20925957. Pmcid: PMC2958877.

  • Pidala J, Anasetti C. Glucocorticoid-refractory acute graft-versus-host disease. Biol Blood Marrow Transplant. 2010 Nov;16(11):1504-1518. Pubmedid: 20096359.

  • Nishihori T, Perkins J, Kim J, Field T, Pidala J, Roman-Diaz J, Komrokji RS, Fernandez HF, Anasetti C, Kharfan-Dabaja MA. Allogeneic hematopoietic cell transplantation for myelofibrosis: a 10-year experience at single institution. Am J Hematol. 2010 Nov;85(11):904-907. Pubmedid: 20890908.

  • Tedeschi SK, Savani BN, Jagasia M, Engelhardt B, Anasetti C, Barrett AJ, Lee S. Time to consider HPV vaccination after allogeneic stem cell transplantation. Biol Blood Marrow Tran. 2010 Aug;16(8):1033-1036. Pubmedid: 20302962. Pmcid: PMC3750708.

  • Hoda D, Pidala J, Salgado-Vila N, Kim J, Perkins J, Bookout R, Field T, Perez L, Ayala E, Ochoa-Bayona JL, Raychaudhuri J, Alsina M, Greene J, Janssen W, Fernandez HF, Anasetti C, Kharfan-Dabaja MA. Sirolimus for treatment of steroid-refractory acute graft-versus-host disease. Bone Marrow Transplant. 2010 Aug;45(8):1347-1351. Pubmedid: 19966849.

  • Perkins J, Field T, Kim J, Kharfan-Dabaja MA, Fernandez H, Ayala E, Perez L, Xu M, Alsina M, Ochoa L, Sullivan D, Janssen W, Anasetti C. A randomized phase II trial comparing tacrolimus and mycophenolate mofetil to tacrolimus and methotrexate for acute graft-versus-host disease prophylaxis. Biol Blood Marrow Tran. 2010 Jul;16(7):937-947. Pubmedid: 20102746.

  • Pidala J, Bloom GC, Enkemann S, Eschrich S, Lancaster J, Anasetti C. Biomarkers to discern transplantation tolerance after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2010 Jun;16(6):729-738. Pubmedid: 19922809.

  • Kharfan-Dabaja MA, Pidala J, Anasetti C. Thrombotic microangiopathy after GVHD prophylaxis with tacrolimus/sirolimus: a call for use of consensus definition in reporting. Blood. 2010 May;115(21):4316-4317. Pubmedid: 20508174.

  • Schriber JR, Anasetti C, Heslop HE, Leahigh AK. Preparing for Growth: Current Capacity and Challenges in Hematopoietic Stem Cell Transplantation Programs. Biol Blood Marrow Transplant. 2010 May;16(5):595-597. Pubmedid: 20167277.

  • Pidala J, Kim J, Perkins J, Field T, Fernandez H, Perez L, Ayala E, Kharfan-Dabaja M, Anasetti C. Mycophenolate mofetil for the management of steroid-refractory acute graft vs host disease. Bone Marrow Transplant. 2010 May;45(5):919-924. Pubmedid: 19767783.

  • Gergis U, Markey K, Greene J, Kharfan-Dabaja M, Field T, Wetzstein G, Schell MJ, Huang Y, Anasetti C, Perkins J. Voriconazole provides effective prophylaxis for invasive fungal infection in patients receiving glucocorticoid therapy for GVHD. Bone Marrow Transplant. 2010 Apr;45(4):662-667. Pubmedid: 19684623. Pmcid: PMC2850960.

  • Pidala J, Anasetti C. Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse?. Haematologica. 2010 Apr;95(4):660-665. Pubmedid: 20015881. Pmcid: PMC2857197.

  • Spellman S, Bray R, Rosen-Bronson S, Haagenson M, Klein J, Flesch S, Vierra-Green C, Anasetti C. The detection of donor-directed, HLA-specific alloantibodies in recipients of unrelated hematopoietic cell transplantation is predictive of graft failure. Blood. 2010 Apr;115(13):2704-2708. Pubmedid: 20089963. Pmcid: PMC2852369.

  • Perez LE, Parquet N, Meads M, Anasetti C, Dalton W. Bortezomib restores stroma-mediated APO2L/TRAIL apoptosis resistance in multiple myeloma. Eur J Haematol. 2010 Mar;84(3):212-222. Pubmedid: 19922463.

  • Iclozan C, Yu Y, Liu C, Liang Y, Yi T, Anasetti C, Yu XZ. T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease. Biol Blood Marrow Tran. 2010 Feb;16(2):170-178. Pubmedid: 19804837. Pmcid: PMC3876952.

  • Field T, Perkins J, Huang Y, Kharfan-Dabaja MA, Alsina M, Ayala E, Fernandez HF, Janssen W, Lancet J, Perez L, Sullivan D, List A, Anasetti C. 5-Azacitidine for myelodysplasia before allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2010 Feb;45(2):255-260. Pubmedid: 19543327.

  • Pidala J, Anasetti C, Jim H. Health-related quality of life following haematopoietic cell transplantation: patient education, evaluation and intervention. Brit J Haematol. 2010 Feb;148(3):373-385. Pubmedid: 19919651. Pmcid: PMC2810350.

  • Field T, Anasetti C. Role and timing of hematopoietic cell transplantation for myelodysplastic syndrome. Mediterr J Hematol Infect Dis. 2010;2(2):e2010019. Pubmedid: 21415970. Pmcid: PMC3033135.

  • Gajewski JL, LeMaistre CF, Silver SM, Lill MC, Selby GB, Horowitz MM, Rizzo JD, Heslop HE, Anasetti C, Maziarz RT. Impending challenges in the hematopoietic stem cell transplantation physician workforce. Biol Blood Marrow Transplant. 2009 Dec;15(12):1493-1501. Pubmedid: 19781658.

  • Pidala J, Anasetti C, Kharfan-Dabaja MA, Cutler C, Sheldon A, Djulbegovic B. Decision analysis of peripheral blood versus bone marrow hematopoietic stem cells for allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2009 Nov;15(11):1415-1421. Pubmedid: 19822301.

  • Pidala J, Kim J, Field T, McBride A, Kharfan-Dabaja M, Perkins J, Fernandez H, Perez L, Ayala E, Anasetti C. Infliximab for managing steroid-refractory acute graft-versus-host disease. Biol Blood Marrow Transplant. 2009 Sep;15(9):1116-1121. Pubmedid: 19660725.

  • Salinger DH, Blough DK, Vicini P, Anasetti C, O'Donnell PV, Sandmaier BM, McCune JS. A limited sampling schedule to estimate individual pharmacokinetic parameters of fludarabine in hematopoietic cell transplant patients. Clin Cancer Res. 2009 Aug;15(16):5280-5287. Pubmedid: 19671874. Pmcid: PMC2763506.

  • Pidala J, Anasetti C, Jim H. Quality of life after allogeneic hematopoietic cell transplantation. Blood. 2009 Jul;114(1):7-19. Pubmedid: 19336756. Pmcid: PMC2710956.

  • Yu Y, Iclozan C, Yamazaki T, Yang X, Anasetti C, Dong C, Yu XZ. Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. Blood. 2009 Jul;114(5):1026-1028. Pubmedid: 19429865. Pmcid: PMC2721783.

  • Pidala J, Kim J, Anasetti C. Sirolimus as primary treatment of acute graft-versus-host disease following allogeneic hematopoietic cell transplantation. Biol Blood Marrow Tran. 2009 Jul;15(7):881-885. Pubmedid: 19539221.

  • Carnevale-Schianca F, Leisenring W, Martin PJ, Furlong T, Schoch G, Anasetti C, Appelbaum FR, Carpenter PA, Deeg HJ, Kiem HP, Storb R, McDonald GB, Nash RA. Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study. Biol Blood Marrow Tr. 2009 Jun;15(6):749-756. Pubmedid: 19450760. Pmcid: PMC2684865.

  • Ringd?n, Pavletic SZ, Anasetti C, Barrett AJ, Wang T, Wang D, Antin JH, Di Bartolomeo P, Bolwell BJ, Bredeson C, Cairo MS, Gale RP, Gupta V, Hahn T, Hale GA, Halter J, Jagasia M, Litzow MR, Locatelli F, Marks DI, McCarthy PL, Cowan MJ, Petersdorf EW, Russell JA, Schiller GJ, Schouten H, Spellman S, Verdonck LF, Wingard JR, Horowitz MM, Arora M. The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation. Blood. 2009 Mar;113(13):3110-3118. Pubmedid: 19059878. Pmcid: PMC2662650.

  • Anasetti C. Selecting donor recipients. Biol Blood Marrow Tran. 2009 Mar;15(3):393-394. Pubmedid: 19203734.

  • Davies SM, Wang D, Wang T, Arora M, Ringden O, Anasetti C, Pavletic S, Casper J, Macmillan ML, Sanders J, Wall D, Kernan NA. Recent decrease in acute graft-versus-host disease in children with leukemia receiving unrelated donor bone marrow transplants. Biol Blood Marrow Tr. 2009 Mar;15(3):360-366. Pubmedid: 19203727. Pmcid: PMC3365559.

  • Hahn T, McCarthy PL , Zhang MJ, Wang D, Arora M, Frangoul H, Gale RP, Hale GA, Horan J, Isola L, Maziarz RT, van Rood JJ, Gupta V, Halter J, Reddy V, Tiberghien P, Litzow M, Anasetti C, Pavletic S, Ringden O. Risk factors for acute graft-versus-host disease after human leukocyte antigen-identical sibling transplants for adults with leukemia. J Clin Oncol. 2009 Jan;26(35):5728-5734. Pubmedid: 18981462. Pmcid: PMC2645611.

  • Anasetti C. What are the most important donor and recipient factors affecting the outcome of related and unrelated allogeneic transplantation?. Best Pract Res Clin Haematol. 2008 Dec;21(4):691-697. Pubmedid: 19041609. Pmcid: PMC3470825.

  • Guo F, Iclozan C, Suh WK, Anasetti C, Yu XZ. CD28 controls differentiation of regulatory T cells from naive CD4 T cells. J Immunol. 2008 Aug;181(4):2285-2291. Pubmedid: 18684917. Pmcid: PMC2688779.

  • Weisdorf D, Spellman S, Haagenson M, Horowitz M, Lee S, Anasetti C, Setterholm M, Drexler R, Maiers M, King R, Confer D, Klein J. Classification of HLA-matching for retrospective analysis of unrelated donor transplantation: revised definitions to predict survival. Biol Blood Marrow Tr. 2008 Jul;14(7):748-758. Pubmedid: 18541193. Pmcid: PMC2668157.

  • Anasetti C. Chemotherapy or allografting for young adults with high-risk ALL. Blood. 2008 Jun;111(12):5755-5755. Pubmedid: 18544698.

  • Perez L, Parquet N, Shain K, Nimmanapalli R, Alsina M, Anasetti C, Dalton W. Bone Marrow Stroma Confers Resistance to Apo2 Ligand/TRAIL in Multiple Myeloma inPart by Regulating c-FLIP. J Immunol. 2008 Feb;180(3):1545-1555. Pubmedid: 18209050.

  • Liang Y, Liu C, Djeu JY, Zhong B, Peters T, Scharffetter-Kochanek K, Anasetti C, Yu XZ. Beta2 integrins separates graft-versus-host disease and graft-versus-leukemia effects. Blood. 2008 Jan;111(2):954-962. Pubmedid: 17928532.

  • Kamani N, Spellman S, Hurley C, Barker J, Smith F, Oudshoorn M, Bray R, Smith A, Williams T, Logan B, Eapen M, Anasetti C, Setterholm M, Confer D. State of the art review: HLA matching and outcome of unrelated donor umbilical cord blood transplants. Biol Blood Marrow Transplant. 2008 Jan;14(1):1-6. Pubmedid: 18158954.

  • Lee S, Klein J, Haagenson M, Baxter-Lowe L, Confer D, Eapen M, Fernandez-Vina M, Flomenberg N, Horowitz M, Hurley C, Noreen H, Oudshoorn M, Petersdorf E, Setterholm M, Spellman S, Weisdorf D, Williams T, Anasetti C. High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood. 2007 Dec;110(13):4576-4583. Pubmedid: 17785583.

  • Eapen M, Logan BR, Confer DL, Haagenson M, Wagner JE, Weisdorf DJ, Wingard JR, Rowley SD, Stroncek D, Gee AP, Horowitz MM, Anasetti C. Peripheral blood grafts from unrelated donors are associated with increased acute and chronic graft-versus-host disease without improved survival. Biol Blood Marrow Tr. 2007 Dec;13(12):1461-1468. Pubmedid: 18022576. Pmcid: PMC2267869.

  • Ferrara J, Anasetti C, Stadtmauer E, Antin J, Wingard J, Lee S, Levine J, Schultz K, Appelbaum F, Negrin R, Giralt S, Bredeson C, Heslop H, Horowitz M. Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2007. Biol Blood Marrow Tr. 2007 Nov;13(11):1268-1285. Pubmedid: 17950914.

  • Kharfan-Dabaja M, Anasetti C, Santos E. Hematopoietic cell transplantation for chronic lymphocytic leukemia: an evolving concept. Biol Blood Marrow Transplant. 2007 Apr;13(4):373-385. Pubmedid: 17382245.

  • Kharfan-Dabaja MA, Anasetti C, Ferrara JL. Sympathectomy protects denervated skin from graft-versus-host disease. Biol Blood Marrow Transplant. 2007 Mar;13(3):369-370. Pubmedid: 17317591.

  • Kharfan-Dabaja MA, Ayala E, Greene J, Rojiani A, Murtagh F, Anasetti C. Two cases of progressive multifocal leukoencephalopathy after allogeneic hematopoietic cell transplantation and a review of the literature. Bone Marrow Transplant. 2007 Feb;39(4):253-254. Pubmedid: 17290282.

  • Anasetti C, Mul? JJ. To ablate or not to ablate? HSCs in the T cell driver's seat. J Clin Invest. 2007 Feb;117(2):306-310. Pubmedid: 17273553. Pmcid: PMC1783831.

  • Kharfan-Dabaja M, Ayala E, Greene J, Rojiani A, Murtagh F, Anasetti C. Two cases of progressive multifocal leukoencephalopathy after allogeneic hematopoietic cell transplantation and a review of the literature. Bone Marrow Transplant. 2007 Jan;39(2): 101-7. Pubmedid: 17143300.

  • Jacobs S, Jacobsen P, Booth-Jones M, Wagner L, Anasetti C. Evaluation of the functional assessment of cancer therapy cognitive scale with hematopoietic stem cell transplant patients. J Pain Symptom Manage. 2007 Jan;33(1):13-23. Pubmedid: 17196903.

  • Green M, Anasetti C, Sandin R, Rolfe N, Greene J. Development of daptomycin resistance in a bone marrow transplant patient with vancomycin-resistant Enterococcus durans. J Oncol Pharm Pract. 2006 Sep;12(3):179-181. Pubmedid: 17022872.

  • Farag S, Bacigalupo A, Eapen M, Hurley C, Dupont B, Caligiuri M, Boudreau C, Nelson G, Oudshoorn M, van Rood J, Velardi A, Maiers M, Setterholm M, Confer D, Posch P, Anasetti C, Kamani N, Miller J, Weisdorf D, Davies S. The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the center for international blood and marrow transplant research. Biol Blood Marrow Transplant. 2006 Aug;12(8):876-884. Pubmedid: 16864058.

  • Yu X, Liang Y, Nurieva R, Guo F, Anasetti C, Dong C. Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. J Immunol. 2006 Jun;176(12):7394-7401. Pubmedid: 16751384.

  • Deeg H, Storer B, Boeckh M, Martin P, McCune J, Myerson D, Heimfeld S, Flowers M, Anasetti C, Doney K, Hansen J, Kiem H, Nash R, O'donnell P, Radich J, Sandmaier B, Scott B, Sorror M, Warren E, Witherspoon R, Woolfrey A, Appelbaum F, Storb R. Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen. Biol Blood Marrow Transplant. 2006 May;12(5):573-584. Pubmedid: 16635793.

  • Jones R, Anasetti C, Appel P, Dipersio J, Heslop H, Lemaistre F, Silver S, Sirilla J, Stiff P. White paper on measurement of quality outcomes. Biol Blood Marrow Transplant. 2006 May;12(5):594-597. Pubmedid: 16635795.

  • Albert M, Anasetti C, Yu X. T regulatory cells as an immunotherapy for transplantation. Expert Opin Biol Ther. 2006 Apr;6(4):315-324. Pubmedid: 16548760.

  • Yu X, Albert M, Anasetti C. Alloantigen Affinity and CD4 Help Determine Severity of Graft-versus-Host Disease Mediated by CD8 Donor T Cells. J Immunol. 2006 Mar;176(6):3383-3390. Pubmedid: 16517706.

  • Anasetti C. The 2006 BBMT Education Supplement. Biol Blood Marrow Transplant. 2006 Jan;12(1):1-1. Pubmedid: 16399576.

  • Anasetti C, Perkins J, Nieder M, Field T. Are matched unrelated donor transplants justified for AML in CR1. Best Pract Res Clin Haematol. 2006;19(2):321-328. Pubmedid: 16516129.

  • Yu X, Anasetti C. Memory stem cells sustain disease. Nat Med. 2005 Dec;11(12):1282-1283. Pubmedid: 16333266.

  • Albert M, Liu Y, Anasetti C, Yu X. Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation. Eur J Immunol. 2005 Oct;35(9):2598-2607. Pubmedid: 16078276.

  • Pavletic S, Khouri I, Haagenson M, King R, Bierman P, Bishop M, Carston M, Giralt S, Molina A, Copelan E, Ringden O, Roy V, Ballen K, Adkins DR, McCarthy P, Weisdorf D, Montserrat E, Anasetti C. Unrelated donor marrow transplantation for B-cell chronic lymphocytic leukemia after using myeloablative conditioning: results from the Center for International Blood and Marrow Transplant Research. J Clin Oncol. 2005 Aug;23(24):5788-5794. Pubmedid: 16043827.

  • Field T, Anasetti C. Selection of unrelated donors for hematopoietic cell transplantation. Curr Hematol Rep. 2005 Jul;4(4):270-275. Pubmedid: 16009041.

  • Nash R, Johnston L, Parker P, McCune J, Storer B, Slattery J, Furlong T, Anasetti C, Appelbaum F, Lloid M, Deeg H, Kiem H, Martin P, Schubert M, Witherspoon R, Forman S, Blume K, Storb R. A phase I/II study of mycophenolate mofetil in combination with cyclosporine for prophylaxis of acute graft-versus-host disease after myeloablative conditioning and allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2005 Jul;11(7):495-505. Pubmedid: 15983549.

  • Carpenter PA, Lowder J, Johnston L, Frangoul H, Khoury H, Parker P, Jerome KA, McCune JS, Storer B, Martin P, Appelbaum F, Abonour R, Westervelt P, Anasetti C. A phase II multicenter study of visilizumab, humanized anti-CD3 antibody, to treat steroid-refractory acute graft-versus-host disease. Biol Blood Marrow Transplant. 2005 Jun;11(6):465-471. Pubmedid: 15931635.

  • Albert M, Yu X, Martin P, Anasetti C. Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin. Blood. 2005 Feb;105(3):1355-1361. Pubmedid: 15459004.

  • Stewart B, Storer B, Storek J, Deeg H, Storb R, Hansen J, Appelbaum F, Carpenter P, Sanders J, Kiem H, Nash R, Petersdorf E, Moravec C, Morton A, Anasetti C, Flowers M, Martin P. Duration of immunosuppressive treatment for chronic graft-versus-host disease. Blood. 2004 Dec;104(12):3501-3506. Pubmedid: 15292060.

  • Flomenberg N, Baxter-Lowe LA, Confer D, Fernandez-Vina M, Filipovich A, Horowitz M, Hurley C, Kollman C, Anasetti C, Noreen H, Begovich A, Hildebrand W, Petersdorf E, Schmeckpeper B, Setterholm M, Trachtenberg E, Williams T, Yunis E, Weisdorf D. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood. 2004 Oct;104(7):1923-1930. Pubmedid: 15191952.

  • Martin PJ, Pei J, Gooley T, Anasetti C, Appelbaum FR, Deeg J, Hansen JA, Nash RA, Petersdorf EW, Storb R, Ghetie V, Schindler J, Vitetta ES. Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation. Biol Blood Marrow Transplant. 2004 Aug;10(8):552-560. Pubmedid: 15282533.

  • Yu XZ, Albert MH, Martin PJ, Anasetti C. CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens. J Clin Invest. 2004 Jun;113(11):1624-1630. Pubmedid: 15173889. Pmcid: PMC419490.

  • Yu XZ, Levin SD, Madrenas J, Anasetti C. Lck is required for activation-induced T cell death after TCR ligation with partial agonists. J Immunol. 2004 Feb;172(3):1437-1443. Pubmedid: 14734719.

  • Petersdorf E, Anasetti C, Martin P, Gooley T, Radich J, Malkki M, WoolfreyA, Smith A, Mickelson E, Hansen J. Limits of HLA mismatching in unrelated hematopoietic cell transplantation. Blood. 2004;104(9):2976-2980. Pubmedid: 15251989.

  • Anasetti C. Advances in the prevention of graft-versus-host disease after hematopoietic cell transplantation. Transplantation. 2004;77(9):S79-S83. Pubmedid: 15201691.

  • Cutler C, Lee S, Greenberg P, Deeg H, Perez W, Anasetti C, Bolwell B, Cairo M, Gale R, Klein J, Lazarus H, Liesveld J, McCarthy P, Milone G, Rizzo J, Schultz K, Trigg M, Keating A, Weisdorf D, Antin J, Horowitz M. A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasiais associated with improved outcome. Blood. 2004;104(2):579-585. Pubmedid: 15039286.

  • Martin P, McDonald G, Sanders J, Anasetti C, Appelbaum F, Deeg H, NashRA, Petersdorf E, Hansen J, Storb R. Increasingly frequent diagnosis of acute gastrointestinal graft-versus-host disease after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2004;10(5):320-327. Pubmedid: 15111931.

  • Deeg H, Gooley T, Flowers M, Sale G, Slattery J, Anasetti C, ChaunceyTR, Doney K, Georges G, Kiem H, Martin P, Petersdorf E, Radich J, SandersJE, Sandmaier B, Warren E, Witherspoon R, Storb R, Appelbaum F. Allogeneic hematopoietic stem cell transplantation for myelofibrosis. Blood. 2003 Dec;102(12):3912-3918. Pubmedid: 12920019.

  • Maris MB, Niederwieser D, Sandmaier BM, Storer B, Stuart M, Maloney D, Petersdorf E, McSweeney P, Pulsipher M, Woolfrey A, Chauncey T, Agura E, Heimfeld S, Slattery J, Hegenbart U, Anasetti C, Blume K, Storb R. HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignancies. Blood. 2003 Sep;102(6):2021-2030. Pubmedid: 12791654.

  • Bornhauser M, Storer B, Slattery JT, Appelbaum FR, Deeg HJ, Hansen J, Martin PJ, McDonald GB, Nichols WG, Radich J, Woolfrey A, Jenke A, Schleyer E, Thiede C, Ehninger G, Anasetti C. Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells. Blood. 2003 Aug;102(3):820-826. Pubmedid: 12676781.

  • McDonald GB, Slattery JT, Bouvier ME, Ren S, Batchelder AL, Kalhorn TF, Schoch HG, Anasetti C, Gooley T. Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation. Blood. 2003 Mar;101(5):2043-2048. Pubmedid: 12406916.

  • Yu X, Martin P, Anasetti C. CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation. J Immunol. 2003 Mar;170(6):3002-3006. Pubmedid: 12626553.

  • Niederwieser D, Maris M, Shizuru JA, Petersdorf E, Hegenbart U, Sandmaier BM, Maloney DG, Storer B, Lange T, Chauncey T, Deininger M, P?nisch W, Anasetti C, Woolfrey A, Little MT, Blume KG, McSweeney PA, Storb RF. Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induce dura. Blood. 2003 Feb;101(4):1620-1629. Pubmedid: 12393457.

  • Hurley C, Baxter Lowe L, Logan B, Karanes C, Anasetti C, Weisdorf D, Confer D. National Marrow Donor Program HLA-matching guidelines for unrelated marrow transplants. Biol Blood Marrow Transplant. 2003;9(10):610-615. Pubmedid: 14569557.

  • Arpinati M, Chirumbolo G, Urbini B, Perrone G, Rondelli D, Anasetti C. Role of plasmacytoid dendritic cells in immunity and tolerance after allogeneic hematopoietic stem cell transplantation. Transpl Immunol. 2003;11(3-4):345-356. Pubmedid: 12967787.

  • Anasetti C. Advances in unrelated donor hematopoietic cell transplantation. Haematologica. 2003;88(3):246-249. Pubmedid: 12651260.

  • Anasetti C. Acquired tolerance to renal allografts in humans. Am J Transplant. 2003;3(3):243-244. Pubmedid: 12614276.

  • Deeg H, Storer B, Slattery J, Anasetti C, Doney K, Hansen J, Kiem H, Martin P, Petersdorf E, Radich J, Sanders J, Shulman H, Warren E, Witherspoon R, Bryant E, Chauncey T, Getzendaner L, Storb R, Appelbaum F. Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome. Blood. 2002 Aug;100(4):1201-1207. Pubmedid: 12149198.

  • Tan P, Mitchell DA, Buss TN, Holmes MA, Anasetti C, Foote J. "Superhumanized" antibodies: reduction of immunogenic potential by complementarity-determining region grafting with human germline sequences: application to an anti-CD28. J Immunol. 2002 Jul;169(2):1119-1125. Pubmedid: 12097421.

  • Koc S, Leisenring W, Flowers M, Anasetti C, Deeg H, Nash R, Sanders J, Witherspoon R, Storb R, Appelbaum F, Martin P. Therapy for chronic graft-versus-host disease: a randomized trial comparing cyclosporine plus prednisone versus prednisone alone. Blood. 2002 Jul;100(1):48-51. Pubmedid: 12070007.

  • Carpenter PA, Appelbaum FR, Corey L, Deeg HJ, Doney K, Gooley T, Krueger J, Martin P, Pavlovic S, Sanders J, Slattery J, Levitt D, Storb R, Woolfrey A, Anasetti C. A humanized non-FcR-binding anti-CD3 antibody, visilizumab, for treatment of steroid-refractory acute graft-versus-host disease. Blood. 2002 Apr;99(8):2712-2719. Pubmedid: 11929757.

  • Anasetti C. Advances in unrelated donor hematopoietic cell transplantation: improved matching and use of blood stem cells. Haematologica. 2002;87:1-3. Pubmedid: 12412381.

  • Rossi M, Arpinati M, Rondelli D, Anasetti C. Plasmacytoid dendritic cells: do they have a role in immune responses after hematopoietic cell transplantation. Hum Immunol. 2002;63(12):1194-1200. Pubmedid: 12480263.

  • Woolfrey A, Anasetti C, Storer B, Doney K, Milner L, Sievers E, Carpenter P, Martin P, Petersdorf E, Appelbaum F, Hansen J, Sanders J. Factors associated with outcome after unrelated marrow transplantation for treatment of acute lymphoblastic leukemia in children. Blood. 2002;99(6):2002-2008. Pubmedid: 11877272.

  • Weisdorf D, Anasetti C, Antin J, Kernan N, Kollman C, Snyder D, Petersdorf E, Nelson G, McGlave P. Allogeneic bone marrow transplantation for chronic myelogenous leukemia: comparative analysis of unrelated versus matched sibling donor transplantation. Blood. 2002;99(6):1971-1977. Pubmedid: 11877268.

  • Platzbecker U, Gooley T, Anasetti C, Appelbaum F, Clurman B, Doney K, Chauncey T, Flowers M, Myerson D, Radich J, Storb R, Witherspoon R, Deeg H. Curative therapy of advanced essential thrombocythemia or polycythemia vera by hemopoietic stem cell transplantation. Leuk Lymphoma. 2002;43(7):1409-1414. Pubmedid: 12389621.

  • Furlong T, Leisenring W, Storb R, Anasetti C, Appelbaum F, Carpenter P, Deeg H, Doney K, Kiem H, Nash R, Sanders J, Witherspoon R, Thompson D, Martin P. Psoralen and ultraviolet A irradiation (PUVA) as therapy for steroid-resistant cutaneous acute graft-versus-host disease. Biol Blood Marrow Transplant. 2002;8(4):206-212. Pubmedid: 12014809.

  • Jurado M, Deeg H, Storer B, Anasetti C, Anderson J, Bryant E, Chauncey T, Doney K, Flowers M, Hansen J, Martin P, Nash R, Petersdorf E, Radich J, SaleG, Sandmaier B, Storb R, Wade J, Witherspoon R, Appelhaum F. Hematopoietic stem cell transplantation for advanced myelodysplastic syndrome after conditioning with busulfan and fractionated total body irradiation is associated with low relapse rate but considerable nonrelapse mortality. Biol Blood Marrow Transplant. 2002;8(3):161-169. Pubmedid: 11939606.

  • Yu X, Anasetti C. Enahancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab')2. Transplantation. 2000;69(1):104-112. Pubmedid: 10653388.

  • Deeg H, Shulman H, Anderson J, Bryant E, Gooley T, Slattery J, Anasetti C, Fefer A, Storb R, Appelbaum F. Allogeneic and syngeneic marrow transplantation for myelodysplastic syndrome in patients 55 to 66 years of age. Blood. 2000;95(4):1188-1194. Pubmedid: 10666189.

  • Arpinati M, Green C, Heimfeld S, Heuser J, Anasetti C. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood. 2000;95(8):2484-2490. Pubmedid: 10753825.

  • Fay JW, Nash RA, Wingard JR, Przepiorka D, Collins RH, Anasetti C, Devine SM, Pi?eiro LA, Storb RF, Aro RM. FK 506-based immunosuppression for prevention of graft versus host disease after unrelated donor marrow transplantation. Transplant P. 1995 Feb;27(1):1374. Pubmedid: 7533383.

  • Pidala J, Kim J, Roman-Diaz J, Shapiro J, Nishihori T, Bookout R, Anasetti C, Kharfan-Dabaja MA. Pentostatin as rescue therapy for glucocorticoid-refractory acute and chronic graft-versus-host disease. Ann Transplant. 15(4):21-29. Pubmedid: 21183872.

Claudio Anasetti M.D.

Dr. Claudio Anasetti is a senior member and chair of the Department of Blood and Marrow Transplant at Moffitt Cancer Center.  He also directs Moffitt’s blood and marrow transplant fellowship program and is a professor of oncology at the University of South Florida.

Dr. Anasetti’s research interests include the prevention and treatment of graft-versus-host disease, blood and bone marrow transplantation and immunogenetics and donor selection. 

Dr. Anasetti graduated cum laude from the University of Perugia School of Medicine in Italy, where he also served a residency in internal medicine.  He completed a fellowship in immunology at Children’s Memorial Hospital in Oklahoma City and an oncology fellowship at the University of Washington – Fred Hutchinson Cancer Research Center in Seattle, WA.

Before coming to Moffitt in 2004, Dr. Anasetti was a member of the faculty at Fred Hutchinson Cancer Research Center and served as medical director of the Unrelated Donor Marrow Transplant Program.

A board member and past president of the American Society of Blood and Marrow Transplantation, Dr. Anasetti is also a charter member of the National Institutes of Health Clinical Oncology Study Section, and chair of the Strategic Capacity Initiative Physician Workforce Group for the National Marrow Donor Program.

In addition, Dr. Anasetti is on several national editor boards and a journal reviewer for numerous professional journals, including the New England Journal of Medicine.

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