C. W. Cruse, MD

BOARD CERTIFICATION:
          •  Plastic Surgery

FELLOWSHIP:

RESIDENCY:
          •  University of Kentucky - Plastic Surgery
          •  University of South Florida - Surgery

MEDICAL SCHOOL:
          •  University of Louisville - MD

• Han D, Yu D, Zhao X, Marzban SS, Messina JL, Gonzalez RJ, Wayne Cruse C, Sarnaik AA, Puleo C, Sondak VK, Zager JS. Sentinel Node Biopsy is Indicated for Thin Melanomas??0.76?mm. Ann Surg Oncol. 2012 Oct;19(11):3335-3342. Pubmedid: 22766986.


• Deneve JL, Messina JL, Marzban SS, Gonzalez RJ, Walls BM, Fisher KJ, Ann Chen Y , Wayne Cruse C, Sondak VK, Zager JS. Merkel cell carcinoma of unknown primary origin. Ann Surg Oncol. 2012 Jul;19(7):2360-2366. Pubmedid: 22271206.


• Gonzalez RJ, Padhya TA, Cherpelis BS, Prince MD, Aya-Ay ML, Sondak VK, Cruse CW, Zager JS. The surgical management of primary and metastatic Merkel cell carcinoma. Curr Probl Cancer. 2010 Jan-Feb;34(1):77-96. Pubmedid: 20371076.


• Messina J, M?ller MG, Sondak VK, Glass FL, Cruse CW. The contoured staged marginal and central surgical excision technique with en face histopathological analysis: useful additions in the armamentarium for treating and diagnosing melanoma in situ. Ann Surg Oncol. 2009 Sep;16(9):2654-2655. Pubmedid: 19588203.


• Raziano RM, Clark GS, Cherpelis BS, Sondak VK, Cruse CW, Fenske NA, Glass LF. Staged margin control techniques for surgical excision of lentigo maligna. G Ital Dermatol Venereol. 2009 Jun;144(3):259-270. Pubmedid: 19528907.


• M?ller MG, Pappas-Politis E, Zager JS, Santiago LA, Yu D, Prakash A, Kinal A, Clark GS, Zhu W, Puleo CA, Glass LF, Messina JL, Sondak VK, Cruse CW. Surgical management of melanoma-in-situ using a staged marginal and central excision technique. Ann Surg Oncol. 2009 Jun;16(6):1526-1536. Pubmedid: 19050971.


• Rollison D, Pawlita M, Giuliano A, Iannacone M, Sondak V, Messina J, Cruse C, Fenske N, Glass L, Kienstra M, Michael K, Waterboer T, Gheit T, Tommasino M. Measures of cutaneous human papillomavirus infection in normal tissues as biomarkers of HPV in corresponding nonmelanoma skin cancers. Int J Cancer. 2008 Nov;123(10):2337-2342. Pubmedid: 18729188.


• Clark G, Pappas-Politis E, Cherpelis B, Messina J, Moller M, Cruse C, Glass L. Surgical management of melanoma in situ on chronically sun-damaged skin. Cancer Control. 2008 Jul;15(3):216-224. Pubmedid: 18596673.


• Riker A, Glass F, Perez I, Cruse C, Messina J, Sondak V. Cutaneous melanoma: methods of biopsy and definitive surgical excision. Dermatol Ther. 2005 Oct;18(5):387-393. Pubmedid: 16297013.


• Puleo C, Messina J, Riker A, Glass L, Nelson C, Cruse C, Johnson T, Sondak V. Sentinel node biopsy for thin melanomas: which patients should be considered?. Cancer Control. 2005 Oct;12(4):230-235. Pubmedid: 16258494.


• Pu L, Cruse C, Wells K, Shons A, Reintgen D. Superficial femoral lymph node dissection after positive sentinel lymphadenectomy for early-stage melanoma of the lower extremity. Ann Plast Surg. 2003;51:69-76. Pubmedid: 12838128.


• Smith D, Messina J, Perrott R, Berman C, Reintgen D, Cruse C, Glass F, DeConti R, Trotti A, Fenske N. Clinical approach to neuroendocrine carcinoma of the skin (Merkel cell carcinoma). Cancer Control. 2000;7(1):72-83. Pubmedid: 10740663.


• Costello D, Powers A, Lynn J, Cruse C, Reintgen D. Surgical management of primary melanoma. Cancer Control. 2000;2(4):307-313. Pubmedid: 11122858.


• Pu LL, Cruse CW, Wells KE, Cantor A, Glass LF, Messina JL, Reintgen DS. Lymphatic mapping and sentinel lymph node biopsy in patients with melanoma of the lower extremity. Plast Reconstr Surg. 1999 Sep;104(4):964-969. Pubmedid: 10654734.


• Brobeil A, Cruse CW, Messina JL, Glass LF, Haddad FF, Berman CG, Marshburn J, Reintgen DS. Cost analysis of sentinel lymph node biopsy as an alternative to elective lymph node dissection in patients with malignant melanoma. Surg Oncol Clin N Am. 1999 Jul;8(3):435-45, viii. Pubmedid: 10448688.


• Haddad FF, Stall A, Messina J, Brobeil A, Ramnath E, Glass LF, Cruse CW, Berman CG, Reintgen DS. The progression of melanoma nodal metastasis is dependent on tumor thickness of the primary lesion. Ann Surg Oncol. 1999 Mar;6(2):144-149. Pubmedid: 10082038.


• Joseph E, Brobeil A, Cruse C, Wells K, Costello D, Reintgen D. Lymphatic mapping for melanomas of the upper extremity. J Hand Surg. 1999;24(4):675-681. Pubmedid: 10447156.


• Messina J, Glass L, Cruse C, Berman C, Ku N, Reintgen D. Pathologic examination of the sentinel lymph node in malignant melanoma. Am J Surg. 1999;23(6):686-690. Pubmedid: 10366151.


• Reintgen D, Cruse C, Wells K. The next revolution in general surgery: radioguided surgery. Ann Surg Oncol. 1999;6(2):125-126. Pubmedid: 10082030.


• Kamath D, Milotes G, Lyman G, Rapaport D, Cruse C, Glass F, Fenske N, Messina J, Berman C, Reintgen D. Cutaneous lymphatic drainage patterns in patients with grossly involved nodal basins. Ann Surg Oncol. 1999;6(4):345-349. Pubmedid: 10379854.


• Wells K, Stadelmann W, Rapaport D, Hamlin R, Cruse C, Reintgen D. Parotid selective lymphadenectomy in malignant melanoma. Ann Plast Surg. 1999;43(1):1-6. Pubmedid: 10402980.


• Powers P, Sarkar S, Goldgof D, Cruse C, Tsap L. Scar assessment: current problems and future solutions. J Burn Care Rehabil. 1999;20(1):54-60. Pubmedid: 9934638.


• Joseph E, Glass F, Glass J, Messina J, DeConti R, Cruse C, Rapaport D, Berman C, Fenske N, Reintgen D. The results of complete lymph node dissection in 83 melanoma patients with positive sentinel nodes. Ann Surg Oncol. 1998;5:119-125. Pubmedid: 9527264.


• Brobeil A, Berman C, Cruse C, DeConti R, Cantor A, Lyman G, Rapaport D, Joseph E, Wells K, Reintgen D. Efficacy of hyperthermic isolated limb perfusion for extremity-confined recurrent melanoma. Ann Surg Oncol. 1998;5(4):376-383. Pubmedid: 9641461.


• Polo M, Ko F, Busillo F, Cruse C, Krizek T, Robson M. Cytokine production in patients with hypertrophic burn scars. J Burn Care Rehabil. 1997;18(6):477-482. Pubmedid: 9404979.


• Reintgen D, Albertini J, Milliotes G, Marshburn J, Cruse C, Rapaport D, Berman C, Glass L, Fenske N, Einstein, Jr. A, Lyman G. Investment in new technology research can save future health care dollars. J Fla Med Assoc. 1997;84(3):175-181. Pubmedid: 9143169.


• Brobeil A, Kamath D, Cruse CW, Rapaport DP, Wells KE, Shons AR, Messina JL, Glass LF, Berman CG, Puleo CA, Reintgen DS. The clinical relevance of sentinel lymph nodes identified with radiolymphoscintigraphy. J Fla Med Assoc. 1997;84(3):157-160. Pubmedid: 9143166.


• Cruse C, Reintgen D, Glass F, Messina J, Trotti, III A, DeConti R. Clinical practice guidelines: neuroendocrine tumors of the skin. Cancer Control. 1997;4:258-260. Pubmedid: noPMID.


• Ramnath E, Kamath D, Brobeil A, Stall A, Kamath V, Cruse C, Glass F, Messina J, Fenske N, Berman C, Cantor A, Cuthbertson D, Reintgen D, Ross M. Lymphatic mapping for melanoma: long-term results of regional nodal sampling with radioguided surgery. Cancer Control. 1997;4:483-490. Pubmedid: 10763056.


• Stadelmann W, Cruse C, Javaheri S, Reintgen D. The use of selective lymphadenectomy in squamous cell carcinoma of the wrist: a case report. J Hand Surg. 1997;22a(4):726-731. Pubmedid: 9260634.


• Wells K, Rapaport D, Cruse C, Payne W, Albertini J, Berman C, Lyman G, Reintgen D. Sentinel node biopsy in melanoma of the head and neck. Plast Reconstr Surg. 1997;100:591-594. Pubmedid: 9283554.


• Lynch C, Pinelli D, Cruse C, Spellacy W, Sinnott J, Shashy R. Maternal death from postpartum necrotizing fascitis arising in an episiotomy: a case report. Infect Dis Obst Gyn. 1997;341-344. Pubmedid: noPMID.


• Kamath D, Cantor A, Glass L, Fenske N, Cruse C, Wells K, Rapaport D, DeConti R, Messina J, Reintgen D. Florida's undeclared epidemic: malignant melanoma. J Fla Med Assoc. 1997;84(3):161-165. Pubmedid: 9143167.


• Joseph E, Messina J, Glass FL, Cruse CW, Rapaport DP, Berman C, Greenberg H, Reintgen DS. Radioguided surgery for the ultrastaging of melanoma. Cancer J Sci Am. 1997;3(6):341-345. Pubmedid: 9403046.


• Messina J, Reintgen D, Cruse C, Rapaport D, Berman C, Fenske N, Glass L. Selective lymphadenectomy in patients with Merkel cell (cutaneous neuroendocrine) carcinoma. Ann Surg Oncol. 1997;4(5):389-395. Pubmedid: 9259965.


• Brobeil A, Rapaport D, Wells K, Cruse C, Glass F, Fenske N, Albertini J, Miliotis G, Messina J, DeConti R, Berman C, Shons A, Cantor A, Reintgen D. Multiple primary melanomas: implications for screening and follow-up programs. Ann Surg Oncol. 1997;4:19-23. Pubmedid: 8985513.


• Berger D, Fieg B, Podoloff D, Norman, Jr. J, Cruse C, Reintgen D, Ross M. Lymphoscintigraphy as a predictor of lymphatic drainage from cutaneous melanoma. Ann Surg Oncol. 1997;4(8):247-251. Pubmedid: 9142386.


• Javaheri S, Cruse C, Stadelmann W, Reintgen D. Sentinel node excision for the diagnosis of metastatic neuroendocrine carcinoma of the skin: a case report. Ann Plast Surg. 1997;39(3):299-302. Pubmedid: 9326712.


• Kamath D, Rapaport D, DeConti R, Cruse C, Wells K, Glass L, Messina J, Fenske N, Brobeil A, Berman C, Puleo C, Reintgen D. Redefining cutaneous lymphatic flow: the necessity of preoperative lymphoscintigraphy in the management of malignant melanoma. J Fla Med Assoc. 1997;84(3):182-187. Pubmedid: 9143170.


• Rapaport D, Stadelmann W, Wells K, Cruse C, Hamlin R, Reintgen D. Parotid gland sentinel lymphadenectomy in malignant melanoma. Melanoma Res. 1997;7:1-6. Pubmedid: noPMID.


• Glass LF, Messina JL, Cruse W, Wells K, Rapaport D, Miliotes G, Berman C, Reintgen D, Fenske NA. The use of intraoperative radiolymphoscintigraphy for sentinel node biopsy in patients with malignant melanoma. Dermatol Surg. 1996 Aug;22(8):715-720. Pubmedid: 8780765.


• Meliotis G, Albertini J, Berman C, Heller R, Messina J, Glass L, Cruse C, Rapaport D, Puleo C, Fenske N, Petsofglov C, DeConti R, Lyman G. The tumor biology of melanoma nodal metastasis. Am Surg. 1996;62:81-88. Pubmedid: 8540654.


• Milotes G, Lyman G, Cruse C, Puleo C, Albertini J, Rapaport D, Glass L, Fenske N, Soriano T, Cuny C, VanVoorhis N, Reintgen D. Evaluation of new patient tumor markers for melanoma. Ann Surg Oncol. 1996;3(6):558-563. Pubmedid: 8915488.


• Glass L, Fenske N, Messina J, Cruse C, Rapaport D, Berman C, Puleo C, Heller R, Miliotes G, Albertini J, Reintgen D. The role of selective lymphadenectomy in the management of patients with malignant melanomoa. Dermatol Surg. 1996;21:979-983.


• Albertini J, Cruse C, Rapaport D, Wells K, DeConti R, Berman C, Jared K, Messina J, Lyman G, Glass L, Fenske N, Reintgen D. Intraoperative radiolymphoscinitigraphy improves sentinel lymph node identification for patients with melanoma. Ann Surg. 1996;223(2):217-224. Pubmedid: 8597518.


• Glass LF, Fenske NA, Messina JL, Cruse CW, Rapaport DP, Berman C, Puleo CA, Heller R, Miliotes G, Albertini J. The role of selective lymphadenectomy in the management of patients with malignant melanoma. Dermatol Surg. 1995 Nov;21(11):979-983. Pubmedid: 7582838.


• Godellas CV, Berman CG, Lyman G, Cruse CW, Rapaport D, Heller R, Wang X, Glass F, Fenske N, Messina J, et a. The identification and mapping of melanoma regional nodal metastases: minimally invasive surgery for the diagnosis of nodal metastases. Am Surg. 1995 Feb;61(2):97-101. Pubmedid: 7856986 .


• Reintgen D, Albertini J, Miliotes G, Berman C, Cruse C, Fenske N, Glasser S, Puleo C, Wang X, Wells K, Rapaport D, DeConti R, Messina J, Heller R. The accurate staging and modern day treatment of malignant melanoma. Cancer Res Ther Cont. 1995;4:183-197. Pubmedid: noPMID.


• Stadelmann W, Cruse C, Messina J. Synovial cell sarcoma of the temporomandibular joint. Ann Plast Surg. 1995;35(6):664-668. Pubmedid: 8748354.


• Reintgen D, Albertini J, Berman C, Cruse C, Fenske N, Glass L, Puleo C, Wang X, Wells K, Rapaport D, DeConti R, Messina J, Heller R. Accurate nodal staging of malignant melanoma. Cancer Control. 1995;2(5):405-414. Pubmedid: 10862181.


• Austin P, Cruse C, Lyman G, Schroer K, Glass L, Reintgen D. Age as a prognostic factor in the malignant melanoma population. Ann Surg Oncol. 1994;1(6):487-494.


• McAllister E, Wells K, Chaet M, Norman Jr. J, Cruse C. Perineal reconstruction after surgical extirpation of pelvic malignancies using the transpelvic transverse rectus abdominal myocutaneous flap. Ann Surg Oncol. 1994;1(2):164-168.


• Wang X, Heller R, Cruse C, VanVoorhis N, Glass L, Fenske N, Berman C, Leo-Messina J, Rapaport D, Wells K, DeConti R, Moscinski L, Stankard C, Puleo C, Reintgen D. Detection of submicroscopic lymph node metasases with polymerase chain reaction in patients with malignant melanoma. Ann Surg. 1994;220:768-774.


• Wells K, Cruse C, Daniels S, Berman C, Norman Jr. J, Reintgen D. The use of lymphoscintigraphy in melanoma of the head and neck. Plast Reconstr Surg. 1994;93:757-761.


• Wells K, Cruse C, Baker J, Daniels S, Stern R, Newman C, Seleznick M, Vasey F, Brozena S, Albers S, Fenske N. The health status of women following cosmetic surgery. Plast Reconstr Surg. 1994;93:907-912.


• Powers P, Cruse C, Daniels S, Stevens B. Posttraumatic stress disorder in patients with burns. J Burn Care Rehabil. 1994;15(2):147-153.


• Reintgen D, Cruse C, Wells K, Berman C, Fenske N, Glass L, Schroer K, Heller R, Ross M, Lyman G, Cox C, Rapaport D, Seigler H, Balch C. The orderly progression of melanoma nodal metastases. Ann Surg. 1994;220(6):759-767.


• Zeller J, Sturm G, Cruse C. Patients with burns are successful in work hardening programs. J Burn Care Rehabil. 1993;14(2):189-196. Pubmedid: 8501108.


• Stankard CE, Cruse C, Wells K, Karl R. Chronic pressure ulcer carcinomas. Ann Plast Surg. 1993;30(3):274-277.


• Reintgen D, Cruse C, Schroer K, Glass L, Saba H, Puleo C, King J, Berman C, Hannon L, Cox C. Computer database for melanoma: a clinical management and research tool to ensure continuous quality assessment. Semin Surg Oncol. 1993;9:208-214.


• Heller R, King B, Baekey P, Cruse C, Reintgen D. The identification of submicroscopic lymph node metastases in patients with malignant melanoma. Semin Surg Oncol. 1993;9:285-289.


• Cruse C, Reintgen D. The treatment of the primary malignant melanoma: a review. Semin Surg Oncol. 1993;9:215-218.


• Norman Jr. J, Wells K, Kearney R, Cruse C, Berman C, Reintgen D. Identification of lymphatic basins in patients with cutaneous melanoma. Semin Surg Oncol. 1993;9:224-227.


• Reintgen D, Cruse C, Berman C, Norman Jr. J. A redefinition of skin mapping with the use of lymphoscintigraphy: implications for elective lymph node dissection for melanoma. Melanoma Res. 1993;3:34-34.


• Powers P, Cruse C, Daniels S, Stevens B. Safety and efficacy of debridement under anesthesia in burn patients. J Burn Care Rehabil. 1993;14(2):176-180.


• Cruse C, Wells K, Reintgen D. Treatment of the primary in malignant melanoma of the skin. Ann Plast Surg. 1992;28(1):22-25.


• Moye S, Cruse C. Bilateral axillary ectopic breast tissue case report and review of the literature. Breast Dis. 1992;5:51-54.


• Wells K, Reintgen D, Cruse C. The current management and prognosis of acral lentiginous melanoma. Ann Plast Surg. 1992;28:100-103.


• Reintgen D, Cruse C, Wells K, Stankard C, Saba H, Schroer K, Cox C, Berman C, Glass L, Alvarez L, Brozena S, Fenske N, Fabri P. The effectiveness of skin cancer screening and continuing education programs toward increasing the survival of patients with malignant melanoma. Surg Oncol. 1992;1:379-384.


• Reintgen D, Cruse C, Wells K, Saba H, Slingluff. Isolated limb perfusion for recurrent melanoma of the extremity. Ann Plast Surg. 1992;28:50-54.


• Heller R, Becker J, Wasselle J, Baekey P, Cruse C, Cox C. Detection of occult lymph node metastases in malignant melanoma. Ann Plast Surg. 1992;28(1):74-77.


• Saba H, Cruse C, Wells K, Klein C, Reintgen D. Malignant melanoma with dacarbazine, carmustine, cisplatin, and tamoxifen regimens: a University of South Florida and H. Lee Moffitt melanoma center study. Ann Plast Surg. 1992;28(1):65-69.


• Cruse C, Wells K, Schroer K, Reintgen D. Etiology and prognosis of local recurrence in malignant melanoma. Ann Plast Surg. 1992;28:26-28.


• Saba H, Cruse C, Wells K, Klein C, Wood H, Reintgen D. Adjuvant chemotherapy in malignant melanoma using DTIC, BCNU, cisplatin and tamoxifen. Ann Plast Surg. 1992;28:60-65.


• Berman C, Norman Jr. J, Cruse C, Reintgen D, Clark R. Lymphoscintigraphy in malignant melanoma. Ann Plast Surg. 1992;28(1):29-32.


• Reintgen D, Cruse C, Wells K, Saba H, Fabri P. The evaluation of putative tumor markers for malignant melanoma. Ann Plast Surg. 1992;28:55-59.


• Riggs D, Weibley R, Daniels S, Wells K, Cruse C. Hot embers and ashes as a source of burns in children. Am J Dis Child. 1992;146:657-658.


• Norman Jr. J, Cruse C, Wells K, Saba H, Reintgen D. Metastatic melanoma with an unknown primary. Ann Plast Surg. 1992;28(1):81-84.


• Cruse C, O'Neill W, Rayhack J. Metastatic basal cell carcinoma of the upper extremity. J Hand Surg. 1992;17(6):1093-1094.


• Stankard C, Cruse C, Cox C, Wells K, King J, Reintgen D. The concept of lymph node dissections in patients with malignant melanoma. Ann Plast Surg. 1992;28:33-38.


• Heller R, Wassalle J, Becker J, Cruse C, Wells K, Cox C, Reintgen D. The detection of submicroscopic lymph node metastases in patients with malignant melanoma. Arch Surg. 1991;126:1455-1460.


• Lewis J, Zager J, Yu D, Pelaez D, Riker A, Dessureault S, Cruse C, Reintgen D, Puleo C, Sondak V. Full-Thickness Grafts Procured from Skin Overlying the Sentinel Lymph Node Basin; Reconstruction of Primary Cutaneous Malignancy Excision Defects. Ann Surg Oncol. 2008 Jun;15(6):1733-1740. Pubmedid: 18379848.

Dr. Wayne Cruse is a plastic surgeon in the Department of Cutaneous Oncology at Moffitt Cancer Center.  He is a professor of surgery and director of the burn fellowship program at the University of South Florida.

His research interests include cutaneous oncology, melanoma, Merkel cell cancer, sarcoma, wounds, treatment for severe burns and cancer reconstruction.

Dr. Cruse received his medical degree from the University of Louisville School of Medicine.  He completed a residency in surgery at the University of South Florida, followed by a plastic surgery residency at the University of Kentucky.

Dr. Cruse has been affiliated with Moffitt since 1986 and was chief of the section of plastic surgery from 1986-1990.  In addition, he was the associate director of Cutaneous Oncology at Moffitt from 2000-2005.  He also served as medical director of the Tampa Bay Regional Burn Center at Tampa General Hospital for six years.

A member of numerous professional organizations, including the American Association of Plastic Surgeons and the American Burn Association, Dr. Cruse served as the assistant commander of burn specialty team 2 with the National Disaster Management System, Department of Homeland Security from 2004-2005.

He has been a guest speaker at numerous medical conferences and has been widely published, including authoring two chapters in Plastic and Reconstructive Surgery:  Essentials for Students for the Plastic Surgery Educational Foundation.